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O29313 (GLNA_ARCFU) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 85. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glutamine synthetase

Short name=GS
EC=6.3.1.2
Alternative name(s):
Glutamate--ammonia ligase
Gene names
Name:glnA
Ordered Locus Names:AF_0949
OrganismArchaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126) [Reference proteome] [HAMAP]
Taxonomic identifier224325 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaArchaeoglobiArchaeoglobalesArchaeoglobaceaeArchaeoglobus

Protein attributes

Sequence length491 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine.

Enzyme regulation

The activity of this enzyme is controlled by adenylation under conditions of abundant glutamine. The fully adenylated enzyme complex is inactive By similarity.

Subcellular location

Cytoplasm Potential.

Sequence similarities

Belongs to the glutamine synthetase family.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionLigase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processglutamine biosynthetic process

Inferred from electronic annotation. Source: InterPro

nitrogen fixation

Inferred from electronic annotation. Source: InterPro

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

glutamate-ammonia ligase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 491491Glutamine synthetase
PRO_0000153201

Amino acid modifications

Modified residue4211O-AMP-tyrosine By similarity

Sequences

Sequence LengthMass (Da)Tools
O29313 [UniParc].

Last modified January 1, 1998. Version 1.
Checksum: 5AADF719AF23F25D

FASTA49155,723
        10         20         30         40         50         60 
MVRRLRGDCM EEVERAKAVL KENNVRQVLC AFADVRGYLQ MFSIPAREFV DGSAFENGIG 

        70         80         90        100        110        120 
FDGSSVRGFR TIEKSDMVWM PDASSLKIIP WIDDPIQKSA IMFGNVYEAW GTEIADCDPR 

       130        140        150        160        170        180 
GYVAKRYEDM LKSEGMSAIF GPEIEFFLFE GVDFTRLSWD MWVSPNGGAG DSWGPPRIMP 

       190        200        210        220        230        240 
ISSELESGYM IRPKEGYFRP PPEDTTVEYR NELVYYLEQL GIDIEYHHHE VATAGQVELD 

       250        260        270        280        290        300 
FKPKQLVDVG DAFYLYKFAA KNIAAMHGLY ATFMPKPLYL DNASGMHTHQ SLWKGEPFSG 

       310        320        330        340        350        360 
EAVFADPDDE YMLSQKARYY IGGLLEHAKA LTALCAPTVN SYKRLVPGFE APIYICWSPR 

       370        380        390        400        410        420 
NRSALVRVPM YVKKPSAIRV EYRGVDPSCN PYLAITAQLA AGLDGIKKKI DPGDPLLEDV 

       430        440        450        460        470        480 
YELTPAQKRE LGVGELPTTL RDAIDHLASD ELMQEVLGSH IFDAFMELKI DEWNQYCLYI 

       490 
TPWEFMKYFD I 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE000782 Genomic DNA. Translation: AAB90294.1.
PIRE69368.
RefSeqNP_069782.1. NC_000917.1.

3D structure databases

ProteinModelPortalO29313.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING224325.AF0949.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAB90294; AAB90294; AF_0949.
GeneID1484172.
KEGGafu:AF0949.

Phylogenomic databases

eggNOGCOG0174.
KOK01915.
OMACMEEVER.
ProtClustDBCLSK2746682.

Enzyme and pathway databases

BioCycAFUL224325:GJBC-971-MONOMER.

Family and domain databases

Gene3D3.10.20.70. 1 hit.
3.30.590.10. 1 hit.
InterProIPR008147. Gln_synt_beta.
IPR014746. Gln_synth/guanido_kin_cat_dom.
IPR008146. Gln_synth_cat_dom.
IPR027303. Gln_synth_gly_rich_site.
IPR004809. Gln_synth_I.
[Graphical view]
PfamPF00120. Gln-synt_C. 1 hit.
PF03951. Gln-synt_N. 1 hit.
[Graphical view]
SUPFAMSSF54368. SSF54368. 1 hit.
TIGRFAMsTIGR00653. GlnA. 1 hit.
PROSITEPS00181. GLNA_ATP. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameGLNA_ARCFU
AccessionPrimary (citable) accession number: O29313
Entry history
Integrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: January 1, 1998
Last modified: February 19, 2014
This is version 85 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families