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O29119 (PGK_ARCFU) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 81. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphoglycerate kinase

EC=2.7.2.3
Gene names
Name:pgk
Ordered Locus Names:AF_1146
OrganismArchaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126) [Reference proteome] [HAMAP]
Taxonomic identifier224325 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaArchaeoglobiArchaeoglobalesArchaeoglobaceaeArchaeoglobus

Protein attributes

Sequence length407 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate. HAMAP-Rule MF_00145

Pathway

Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5. HAMAP-Rule MF_00145

Subcellular location

Cytoplasm Potential HAMAP-Rule MF_00145.

Sequence similarities

Belongs to the phosphoglycerate kinase family.

Ontologies

Keywords
   Biological processGlycolysis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processglycolysis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

phosphoglycerate kinase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 407407Phosphoglycerate kinase HAMAP-Rule MF_00145
PRO_0000146050

Regions

Nucleotide binding355 – 3584ATP By similarity
Region24 – 263Substrate binding By similarity
Region60 – 634Substrate binding By similarity

Sites

Binding site391Substrate By similarity
Binding site1171Substrate By similarity
Binding site1571Substrate By similarity
Binding site3301ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
O29119 [UniParc].

Last modified January 1, 1998. Version 1.
Checksum: 6AD2E431E7DBD799

FASTA40745,278
        10         20         30         40         50         60 
MMIDGLPTLD DIPYRGKHVL LRVDINAPIV NSTILDTSRF ESHIPTIEAL EDSKLVLLAH 

        70         80         90        100        110        120 
QSRPGKKDFT SLESHASTLS KLLGKRVEYI DEIFSKGVLR RIKEMENGEV ILLENVRFYS 

       130        140        150        160        170        180 
EEQLNRSAEE HAECHMVRKL STAFDLFVND AFSASHRSHA SLVGFVPVLP SVVGRLVENE 

       190        200        210        220        230        240 
VTALSKPLKG EGRKIFVLGG AKIKDSVKVL KNVLENNIAE KVVLTGVVAN YFLMLKGYDI 

       250        260        270        280        290        300 
GEVNRKVVED NKEDVSDEEM INILKKYSDK IILPIDLGIE KDGVRVDIPL EKFDGKYRIM 

       310        320        330        340        350        360 
DIGLETVNQL SEIIPKYDYV VLNGPAGVFE DERFSLGTYE ILRAATRAGY SVVGGGHIAS 

       370        380        390        400 
AARLFGLSDK FSHISTAGGA CIRFLSGEKL VALEVIKEYW AKKWGKS 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE000782 Genomic DNA. Translation: AAB90100.1.
PIRA69393.
RefSeqNP_069975.1. NC_000917.1.

3D structure databases

ProteinModelPortalO29119.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING224325.AF1146.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAB90100; AAB90100; AF_1146.
GeneID1484370.
KEGGafu:AF1146.

Phylogenomic databases

eggNOGCOG0126.
KOK00927.
OMADMIFDIG.
ProtClustDBCLSK2746771.

Enzyme and pathway databases

BioCycAFUL224325:GJBC-1170-MONOMER.
UniPathwayUPA00109; UER00185.

Family and domain databases

Gene3D3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPMF_00145. Phosphoglyc_kinase.
InterProIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERPTHR11406. PTHR11406. 1 hit.
PfamPF00162. PGK. 1 hit.
[Graphical view]
PIRSFPIRSF000724. Pgk. 1 hit.
PRINTSPR00477. PHGLYCKINASE.
SUPFAMSSF53748. SSF53748. 1 hit.
PROSITEPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePGK_ARCFU
AccessionPrimary (citable) accession number: O29119
Entry history
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: January 1, 1998
Last modified: February 19, 2014
This is version 81 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways