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O29027 (GSA_ARCFU) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 101. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glutamate-1-semialdehyde 2,1-aminomutase

Short name=GSA
EC=5.4.3.8
Alternative name(s):
Glutamate-1-semialdehyde aminotransferase
Short name=GSA-AT
Gene names
Name:hemL
Ordered Locus Names:AF_1241
OrganismArchaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126) [Reference proteome] [HAMAP]
Taxonomic identifier224325 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaArchaeoglobiArchaeoglobalesArchaeoglobaceaeArchaeoglobus

Protein attributes

Sequence length418 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Ontologies

Keywords
   Biological processPorphyrin biosynthesis
   Cellular componentCytoplasm
   LigandPyridoxal phosphate
   Molecular functionIsomerase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processprotoporphyrinogen IX biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionglutamate-1-semialdehyde 2,1-aminomutase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

pyridoxal phosphate binding

Inferred from electronic annotation. Source: InterPro

transaminase activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 418418Glutamate-1-semialdehyde 2,1-aminomutase HAMAP-Rule MF_00375
PRO_0000120477

Amino acid modifications

Modified residue2621N6-(pyridoxal phosphate)lysine By similarity

Sequences

Sequence LengthMass (Da)Tools
O29027 [UniParc].

Last modified January 1, 1998. Version 1.
Checksum: C8223AB4A06E6443

FASTA41845,754
        10         20         30         40         50         60 
MKLDKSRKLY AEALNLMPGG VSSPVRAFKP HPFYTARGKG SKIYDVDGNA YIDYCMAYGP 

        70         80         90        100        110        120 
LVLGHANEVV KNALAEQLER GWLYGTPIEL EIEYAKLIQK YFPSMEMLRF VNTGSEATMA 

       130        140        150        160        170        180 
ALRVARGFTG RDKIVKVEGS FHGAHDAVLV KAGSGATTHG IPNSAGVPAD FVKNTLQVPF 

       190        200        210        220        230        240 
NDIEALSEIL EKNEVAALIL EPVMGNSSLI LPEKDYLKEV RKVTAENDVL LIFDEVITGF 

       250        260        270        280        290        300 
RVSMGGAQEY YGVKPDLTTL GKIAGGGLPI GIFGGRKEIM ERVAPSGDVY QAGTFSGNPL 

       310        320        330        340        350        360 
SLTAGYATVK FMEENGVIEK VNSLTEKLVS GIADVLEDKK AECEVGSLAS MFCIYFGPTP 

       370        380        390        400        410 
RNYAEALQLN KERFMEFFWR MLENGVFLPP SQYETCFVSF AHTEEDVEKT VEAVSESL 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE000782 Genomic DNA. Translation: AAB90001.1.
PIRH69404.
RefSeqNP_070069.1. NC_000917.1.

3D structure databases

ProteinModelPortalO29027.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING224325.AF1241.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAB90001; AAB90001; AF_1241.
GeneID1484465.
KEGGafu:AF1241.

Phylogenomic databases

eggNOGCOG0001.
KOK01845.
OMARAIKPYP.

Enzyme and pathway databases

BioCycAFUL224325:GJBC-1266-MONOMER.
UniPathwayUPA00251; UER00317.

Family and domain databases

Gene3D3.40.640.10. 1 hit.
3.90.1150.10. 2 hits.
HAMAPMF_00375. HemL_aminotrans_3.
InterProIPR004639. 4pyrrol_synth_GluAld_NH2Trfase.
IPR005814. Aminotrans_3.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PANTHERPTHR11986. PTHR11986. 1 hit.
PfamPF00202. Aminotran_3. 1 hit.
[Graphical view]
PIRSFPIRSF000521. Transaminase_4ab_Lys_Orn. 1 hit.
SUPFAMSSF53383. SSF53383. 1 hit.
TIGRFAMsTIGR00713. hemL. 1 hit.
PROSITEPS00600. AA_TRANSFER_CLASS_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameGSA_ARCFU
AccessionPrimary (citable) accession number: O29027
Entry history
Integrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: January 1, 1998
Last modified: May 14, 2014
This is version 101 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways