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Protein

Riboflavin synthase

Gene

ribC

Organism
Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

2 6,7-dimethyl-8-(1-D-ribityl)lumazine = riboflavin + 4-(1-D-ribitylamino)-5-amino-2,6-dihydroxypyrimidine.

Pathwayi: riboflavin biosynthesis

This protein is involved in step 2 of the subpathway that synthesizes riboflavin from 2-hydroxy-3-oxobutyl phosphate and 5-amino-6-(D-ribitylamino)uracil.
Proteins known to be involved in the 2 steps of the subpathway in this organism are:
  1. 6,7-dimethyl-8-ribityllumazine synthase (ribH)
  2. Riboflavin synthase (ribC)
This subpathway is part of the pathway riboflavin biosynthesis, which is itself part of Cofactor biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes riboflavin from 2-hydroxy-3-oxobutyl phosphate and 5-amino-6-(D-ribitylamino)uracil, the pathway riboflavin biosynthesis and in Cofactor biosynthesis.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionTransferase
Biological processRiboflavin biosynthesis

Enzyme and pathway databases

UniPathwayiUPA00275; UER00405

Names & Taxonomyi

Protein namesi
Recommended name:
Riboflavin synthase (EC:2.5.1.9)
Gene namesi
Name:ribC
Ordered Locus Names:AF_1416
OrganismiArchaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)
Taxonomic identifieri224325 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaArchaeoglobiArchaeoglobalesArchaeoglobaceaeArchaeoglobus
Proteomesi
  • UP000002199 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001348591 – 153Riboflavin synthaseAdd BLAST153

Interactioni

Protein-protein interaction databases

STRINGi224325.AF1416

Structurei

3D structure databases

ProteinModelPortaliO28856
SMRiO28856
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the DMRL synthase family.Curated

Phylogenomic databases

eggNOGiarCOG01322 Archaea
COG1731 LUCA
KOiK00793
OMAiLMTNTHI
OrthoDBiPOG093Z0DB2

Family and domain databases

CDDicd09210 Riboflavin_synthase_archaeal, 1 hit
Gene3Di3.40.50.960, 1 hit
InterProiView protein in InterPro
IPR002180 LS/RS
IPR036467 LS/RS_sf
IPR006399 Ribfl_synth_arc
PfamiView protein in Pfam
PF00885 DMRL_synthase, 1 hit
PIRSFiPIRSF015750 Ribfl_synth_arc, 1 hit
SUPFAMiSSF52121 SSF52121, 1 hit
TIGRFAMsiTIGR01506 ribC_arch, 1 hit

Sequencei

Sequence statusi: Complete.

O28856-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKIGIADTTF SRINMGKIAI DELRKISSIP YERYTVPGIK DLPIAAKKLL
60 70 80 90 100
EEKGCDIVIT LGWVGGTQKD MLSYIVLSMG LVIVQLMTNK HVIDVTIHED
110 120 130 140 150
EAEDEKTLMM VAENRVREHV RNAVDLLVNP KRLQKLAGTG QRQGYPDVGP

ILK
Length:153
Mass (Da):17,083
Last modified:January 1, 1998 - v1
Checksum:iC64E3D55752A9F37
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000782 Genomic DNA Translation: AAB89831.1
PIRiG69426
RefSeqiWP_010878913.1, NC_000917.1

Genome annotation databases

EnsemblBacteriaiAAB89831; AAB89831; AF_1416
GeneIDi24795028
KEGGiafu:AF_1416

Similar proteinsi

Entry informationi

Entry nameiRISC_ARCFU
AccessioniPrimary (citable) accession number: O28856
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: January 1, 1998
Last modified: March 28, 2018
This is version 99 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

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