Reviewed, UniProtKB/Swiss-Prot O28847 (APGM2_ARCFU)

Names and origin

Protein names

Recommended name:
    2,3-bisphosphoglycerate-independent phosphoglycerate mutase 2
      Short name=Phosphoglyceromutase 2
      Short name=BPG-independent PGAM 2
      Short name=aPGAM 2
    EC=5.4.2.1

Gene names

Name:	apgM2
Ordered Locus Names:	AF_1425

Organism

Archaeoglobus fulgidus [Complete proteome] [HAMAP]

Taxonomic identifier

2234 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Archaeoglobi › Archaeoglobales › Archaeoglobaceae › Archaeoglobus

Protein attributes

Sequence length	380 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate By similarity.
Catalytic activity	2-phospho-D-glycerate = 3-phospho-D-glycerate. HAMAP MF_01402
Pathway	Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 3/5. HAMAP MF_01402
Sequence similarities	Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.

Ontologies

Keywords
Biological process	Glycolysis
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycolysis Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity Inferred from electronic annotation. Source: HAMAP metal ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 380	380	2,3-bisphosphoglycerate-independent phosphoglycerate mutase 2 HAMAP MF_01402		PRO_0000138132

Sequences

	Sequence		Length	Mass (Da)
	O28847-1 [UniParc]. Last modified January 1, 1998. Version 1. Checksum: E90DE95BDE300DF8	FASTA	380	42,457
	10 20 30 40 50 60 MKYLLLIPDG MADWEVEELD GRTPLEVAET ENMDFLAKEG ACGIAKTVPD GFEPGSDVAN 70 80 90 100 110 120 LTILGVDVRK HYTGRGPIEA LARGVKGKLV FRCNLVKVED GVMVDYSGGR ISDEEARKVI 130 140 150 160 170 180 EELNRAKPYD FVKFYAGKSY RNLLVINKDF RDDVKTFPPH DITGKEIDKH LPSGGELAEL 190 200 210 220 230 240 LKELMGWSAE ILPEITDKAN MIWPWGGGRM PSFPNFGQRY GLRGAMITEV DLLEGIARGM 250 260 270 280 290 300 GMEVVQVEGI TGYIDTNYRG LVRETARALE EHDFVVLHTE GIDEVGHEGD AELKVRAIEL 310 320 330 340 350 360 YDSKIVGKLL NKVDLDETRI LLLPDHPTPV KVKTHVAEPV PFTLYGRGRD EVKVYTEKSC 370 380 RRGKFGLVDG LRLMDLLIKK

References

[1]

"The complete genome sequence of the hyperthermophilic, sulphate-reducing archaeon Archaeoglobus fulgidus." Klenk H.-P., Clayton R.A., Tomb J.-F., White O., Nelson K.E., Ketchum K.A., Dodson R.J., Gwinn M.L., Hickey E.K., Peterson J.D., Richardson D.L., Kerlavage A.R., Graham D.E., Kyrpides N.C., Fleischmann R.D., Quackenbush J., Lee N.H., Sutton G.G. , Gill S.R., Kirkness E.F., Dougherty B.A., McKenney K., Adams M.D., Loftus B.J., Peterson S.N., Reich C.I., McNeil L.K., Badger J.H., Glodek A., Zhou L., Overbeek R., Gocayne J.D., Weidman J.F., McDonald L.A., Utterback T.R., Cotton M.D., Spriggs T., Artiach P., Kaine B.P., Sykes S.M., Sadow P.W., D'Andrea K.P., Bowman C., Fujii C., Garland S.A., Mason T.M., Olsen G.J., Fraser C.M., Smith H.O., Woese C.R., Venter J.C. Nature 390:364-370(1997) [PubMed: 9389475] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE000782 Genomic DNA. Translation: AAB89821.1.
PIR	H69427.
RefSeq	NP_070254.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	1484649.
GenomeReviews	Gene locus AF_1425 in contig AE000782_GR.
KEGG	afu:AF1425.
NMPDR	fig|224325.1.peg.1415.
TIGR	AF_1425.
Phylogenomic databases
HOGENOM	O28847.
OMA	GATGYLD.
Enzyme and pathway databases
BioCyc	AFUL224325:AF_1425-MON.
BRENDA	5.4.2.1. 7576.
Family and domain databases
HAMAP	MF_01402. [Tree]
InterPro	IPR004456. APGAM_arc. IPR019304. bisP-indep_Pglycerate_Mutase. IPR013371. Homoserine_kin_put. IPR006124. Metalloenzyme. [Graphical view]
Pfam	PF01676. Metalloenzyme. 1 hit. PF10143. PhosphMutase. 1 hit. [Graphical view]
PIRSF	PIRSF006392. IPGAM_arch. 1 hit.
ProDom	PD004704. APGAM_DeoB. 1 hit. [Graphical view] [Entries sharing at least one domain]
TIGRFAMs	TIGR00306. apgM. 1 hit. TIGR02535. hyp_Hser_kinase. 1 hit.
ProtoNet	Search...

Entry information

Entry name

APGM2_ARCFU

Accession

Primary (citable) accession number: O28847

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 2, 2002
Last sequence update:	January 1, 1998
Last modified:	November 3, 2009
This is version 54 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)