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O28786 (CAPPA_ARCFU) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 73. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphoenolpyruvate carboxylase

Short name=PEPC
Short name=PEPCase
EC=4.1.1.31
Gene names
Name:ppcA
Ordered Locus Names:AF_1486
OrganismArchaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126) [Reference proteome] [HAMAP]
Taxonomic identifier224325 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaArchaeoglobiArchaeoglobalesArchaeoglobaceaeArchaeoglobus

Protein attributes

Sequence length471 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle By similarity. HAMAP-Rule MF_01904

Catalytic activity

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-. HAMAP-Rule MF_01904

Cofactor

Magnesium By similarity. HAMAP-Rule MF_01904

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_01904

Sequence similarities

Belongs to the PEPCase type 2 family.

Ontologies

Keywords
   Biological processCarbon dioxide fixation
   LigandMagnesium
   Molecular functionLyase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processcarbon fixation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

oxaloacetate metabolic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

tricarboxylic acid cycle

Inferred from electronic annotation. Source: InterPro

   Molecular_functionmagnesium ion binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

phosphoenolpyruvate carboxylase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 471471Phosphoenolpyruvate carboxylase HAMAP-Rule MF_01904
PRO_0000309598

Sequences

Sequence LengthMass (Da)Tools
O28786 [UniParc].

Last modified January 1, 1998. Version 1.
Checksum: 892A03A47FBDA771

FASTA47154,166
        10         20         30         40         50         60 
MVPRVMSTQH PDNARIPFFA ASEVLNGEDE VREAYYVFSH FKCDEQMWDF EGKEADAHIV 

        70         80         90        100        110        120 
RKLLSSYYDF FSSRPLGKDF RLTMRVPNPE IEKGEAKLLA ETLEMIPRSY DYVRSLGIEH 

       130        140        150        160        170        180 
PPIFEVILPM TRSAEEVMKV HAFYRDFVAG KGRFELLGEK VSDWLGDFLP EEIKVIPLFE 

       190        200        210        220        230        240 
DRDSLMRAAE ISERYAEWAE LDELRVFLAR SDPAMNYGFV AATIYVKKAL YDLSQLGIST 

       250        260        270        280        290        300 
YPILGVGSCP FRGGFSPKNL SVLDEFPSVY TFTVQSAFKY DYEFGDVRRA IKRAKEAARR 

       310        320        330        340        350        360 
KSDYVDEEHL QVAEKLKDGY RRRIAKIAEI VNRISSRIPR RRMRKLHVGL FGYSRGEEIK 

       370        380        390        400        410        420 
LPRAITFCAS LYSIGLPSEI IGIAEMSDKD YEAVCEVFKN FDGMMESAMS LFNPESLKIV 

       430        440        450        460        470 
DLSMDFERAK ELFGYEPDER HLEKTNEIIK QIDGDIKNLV VEAGILRGFL G 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE000782 Genomic DNA. Translation: AAB89769.1.
PIRE69435.
RefSeqNP_070315.1. NC_000917.1.

3D structure databases

ProteinModelPortalO28786.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING224325.AF1486.

Protocols and materials databases

DNASU1484712.
StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAB89769; AAB89769; AF_1486.
GeneID1484712.
KEGGafu:AF1486.

Phylogenomic databases

eggNOGCOG1892.
KOK01595.
OMADEYMPDY.

Enzyme and pathway databases

BioCycAFUL224325:GJBC-1519-MONOMER.

Family and domain databases

HAMAPMF_01904. PEPcase_type2.
InterProIPR007566. PEP_COase_arc-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamPF14010. PEPcase_2. 1 hit.
[Graphical view]
PIRSFPIRSF006677. UCP006677. 1 hit.
SUPFAMSSF51621. SSF51621. 1 hit.
TIGRFAMsTIGR02751. PEPCase_arch. 1 hit.
ProtoNetSearch...

Entry information

Entry nameCAPPA_ARCFU
AccessionPrimary (citable) accession number: O28786
Entry history
Integrated into UniProtKB/Swiss-Prot: November 13, 2007
Last sequence update: January 1, 1998
Last modified: May 14, 2014
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families