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O28786

- CAPPA_ARCFU

UniProt

O28786 - CAPPA_ARCFU

Protein

Phosphoenolpyruvate carboxylase

Gene

ppcA

Organism
Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 75 (01 Oct 2014)
      Sequence version 1 (01 Jan 1998)
      Previous versions | rss
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    Functioni

    Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

    Catalytic activityi

    Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotation

    Cofactori

    Magnesium.UniRule annotation

    GO - Molecular functioni

    1. magnesium ion binding Source: UniProtKB-HAMAP
    2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. carbon fixation Source: UniProtKB-HAMAP
    2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
    3. tricarboxylic acid cycle Source: InterPro

    Keywords - Molecular functioni

    Lyase

    Keywords - Biological processi

    Carbon dioxide fixation

    Keywords - Ligandi

    Magnesium

    Enzyme and pathway databases

    BioCyciAFUL224325:GJBC-1519-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
    Short name:
    PEPCUniRule annotation
    Short name:
    PEPCaseUniRule annotation
    Gene namesi
    Name:ppcAUniRule annotation
    Ordered Locus Names:AF_1486
    OrganismiArchaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)
    Taxonomic identifieri224325 [NCBI]
    Taxonomic lineageiArchaeaEuryarchaeotaArchaeoglobiArchaeoglobalesArchaeoglobaceaeArchaeoglobus
    ProteomesiUP000002199: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 471471Phosphoenolpyruvate carboxylasePRO_0000309598Add
    BLAST

    Interactioni

    Subunit structurei

    Homotetramer.UniRule annotation

    Protein-protein interaction databases

    STRINGi224325.AF1486.

    Structurei

    3D structure databases

    ProteinModelPortaliO28786.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the PEPCase type 2 family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG1892.
    KOiK01595.
    OMAiDEYMPDY.

    Family and domain databases

    HAMAPiMF_01904. PEPcase_type2.
    InterProiIPR007566. PEP_COase_arc-type.
    IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
    [Graphical view]
    PfamiPF14010. PEPcase_2. 1 hit.
    [Graphical view]
    PIRSFiPIRSF006677. UCP006677. 1 hit.
    SUPFAMiSSF51621. SSF51621. 1 hit.
    TIGRFAMsiTIGR02751. PEPCase_arch. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    O28786-1 [UniParc]FASTAAdd to Basket

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    MVPRVMSTQH PDNARIPFFA ASEVLNGEDE VREAYYVFSH FKCDEQMWDF    50
    EGKEADAHIV RKLLSSYYDF FSSRPLGKDF RLTMRVPNPE IEKGEAKLLA 100
    ETLEMIPRSY DYVRSLGIEH PPIFEVILPM TRSAEEVMKV HAFYRDFVAG 150
    KGRFELLGEK VSDWLGDFLP EEIKVIPLFE DRDSLMRAAE ISERYAEWAE 200
    LDELRVFLAR SDPAMNYGFV AATIYVKKAL YDLSQLGIST YPILGVGSCP 250
    FRGGFSPKNL SVLDEFPSVY TFTVQSAFKY DYEFGDVRRA IKRAKEAARR 300
    KSDYVDEEHL QVAEKLKDGY RRRIAKIAEI VNRISSRIPR RRMRKLHVGL 350
    FGYSRGEEIK LPRAITFCAS LYSIGLPSEI IGIAEMSDKD YEAVCEVFKN 400
    FDGMMESAMS LFNPESLKIV DLSMDFERAK ELFGYEPDER HLEKTNEIIK 450
    QIDGDIKNLV VEAGILRGFL G 471
    Length:471
    Mass (Da):54,166
    Last modified:January 1, 1998 - v1
    Checksum:i892A03A47FBDA771
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE000782 Genomic DNA. Translation: AAB89769.1.
    PIRiE69435.
    RefSeqiNP_070315.1. NC_000917.1.
    WP_010878983.1. NC_000917.1.

    Genome annotation databases

    EnsemblBacteriaiAAB89769; AAB89769; AF_1486.
    GeneIDi1484712.
    KEGGiafu:AF1486.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE000782 Genomic DNA. Translation: AAB89769.1 .
    PIRi E69435.
    RefSeqi NP_070315.1. NC_000917.1.
    WP_010878983.1. NC_000917.1.

    3D structure databases

    ProteinModelPortali O28786.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 224325.AF1486.

    Protocols and materials databases

    DNASUi 1484712.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAB89769 ; AAB89769 ; AF_1486 .
    GeneIDi 1484712.
    KEGGi afu:AF1486.

    Phylogenomic databases

    eggNOGi COG1892.
    KOi K01595.
    OMAi DEYMPDY.

    Enzyme and pathway databases

    BioCyci AFUL224325:GJBC-1519-MONOMER.

    Family and domain databases

    HAMAPi MF_01904. PEPcase_type2.
    InterProi IPR007566. PEP_COase_arc-type.
    IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
    [Graphical view ]
    Pfami PF14010. PEPcase_2. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF006677. UCP006677. 1 hit.
    SUPFAMi SSF51621. SSF51621. 1 hit.
    TIGRFAMsi TIGR02751. PEPCase_arch. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "The complete genome sequence of the hyperthermophilic, sulphate-reducing archaeon Archaeoglobus fulgidus."
      Klenk H.-P., Clayton R.A., Tomb J.-F., White O., Nelson K.E., Ketchum K.A., Dodson R.J., Gwinn M.L., Hickey E.K., Peterson J.D., Richardson D.L., Kerlavage A.R., Graham D.E., Kyrpides N.C., Fleischmann R.D., Quackenbush J., Lee N.H., Sutton G.G.
      , Gill S.R., Kirkness E.F., Dougherty B.A., McKenney K., Adams M.D., Loftus B.J., Peterson S.N., Reich C.I., McNeil L.K., Badger J.H., Glodek A., Zhou L., Overbeek R., Gocayne J.D., Weidman J.F., McDonald L.A., Utterback T.R., Cotton M.D., Spriggs T., Artiach P., Kaine B.P., Sykes S.M., Sadow P.W., D'Andrea K.P., Bowman C., Fujii C., Garland S.A., Mason T.M., Olsen G.J., Fraser C.M., Smith H.O., Woese C.R., Venter J.C.
      Nature 390:364-370(1997) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126.

    Entry informationi

    Entry nameiCAPPA_ARCFU
    AccessioniPrimary (citable) accession number: O28786
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 13, 2007
    Last sequence update: January 1, 1998
    Last modified: October 1, 2014
    This is version 75 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3