Skip Header

Contribute Send feedback
Read comments (?) or add your own

O28783 (IORA_ARCFU) Reviewed, UniProtKB/Swiss-Prot

Last modified November 16, 2011. Version 80. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Indolepyruvate oxidoreductase subunit iorA
Short name=IOR
EC=1.2.7.8
Alternative name(s):
Indolepyruvate ferredoxin oxidoreductase subunit alpha
Gene names
Name:iorA
Ordered Locus Names:AF_1489
OrganismArchaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)
Taxonomic identifier224325 [NCBI]
Taxonomic lineageArchaea › Euryarchaeota › Archaeoglobi › Archaeoglobales › Archaeoglobaceae › Archaeoglobus

Protein attributes

Sequence length623 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates By similarity.

Catalytic activity

(Indol-3-yl)pyruvate + CoA + 2 oxidized ferredoxin = S-2-(indol-3-yl)acetyl-CoA + CO2 + 2 reduced ferredoxin + H+.

Cofactor

Binds 1 4Fe-4S cluster.

Subunit structure

Heterodimer of the iorA and iorB subunits.

Sequence similarities

Contains 1 4Fe-4S ferredoxin-type domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 623623Indolepyruvate oxidoreductase subunit iorA
PRO_0000099925

Regions

Domain593 – 622304Fe-4S ferredoxin-type

Sites

Metal binding6021Iron-sulfur (4Fe-4S) Potential
Metal binding6051Iron-sulfur (4Fe-4S) Potential
Metal binding6081Iron-sulfur (4Fe-4S) Potential
Metal binding6121Iron-sulfur (4Fe-4S) Potential

Sequences

Sequence LengthMass (Da)Tools
O28783 [UniParc].

Last modified January 1, 1998. Version 1.
Checksum: 9B55E1CDC3860D56

FASTA62367,798
        10         20         30         40         50         60 
MLNDVVRDAE GEKVFLLGNE AIARGAIEAG IDVFAAYPGT PSSEIADTLS DACRLLRGKM 

        70         80         90        100        110        120 
DFYMEYSANE KVAFEVAVGA SLAGKRAMAT MKHVGVNVAA DPLFSFAYVG ARGGFVLVTA 

       130        140        150        160        170        180 
DDPSMHSSQN EQDNRWYGKA AKLPVVEPSS VQEAKDYAKL CFDLSEKFGL PMILRSYTRL 

       190        200        210        220        230        240 
SHASGVVELG KIPEKEFSRV EWERHPETDV VLPAHARKLK PILLEKLEKI ERYFNSSEMN 

       250        260        270        280        290        300 
WVDEGDGDVG IIACGLSYAY TKEALENLNL NLPVLKLSSM HPLPERLIEN FVSQMKKVIV 

       310        320        330        340        350        360 
VEEVDPFVEL HVRAMGLAEV YGKMNGYMPM NYEYNVGRVE TGIAKALGIK PSRDYEGIVA 

       370        380        390        400        410        420 
ESQKLAAKAP PRPPVLCPGC PHSASFYAIR RVVDELGDAA LPSDIGCYTL GINKPLEGVD 

       430        440        450        460        470        480 
ITICMGASVG VSNGLAHVLN NKIIATIGDS TFIHAGIPPL INAVYNHADF VLVILDNSTT 

       490        500        510        520        530        540 
GMTGHQPHPG TGFRGCGEAG KAVRIEDIVR GCGVEFVEVV NPYNVRKMVD VLRRALNHDG 

       550        560        570        580        590        600 
VAVVIARQPC AILWSRARRR EGKIVTYKVT EDCTLCMECV NTFACPALIF DGEKVSIDQS 

       610        620 
LCVGCAVCAK ICPNRAIKPA KSN

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE000782 Genomic DNA. Translation: AAB89760.1.
PIRH69435.
RefSeqNP_070318.1. NC_000917.1.

3D structure databases

ProteinModelPortalO28783.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1484716.
GenomeReviewsGene locus AF_1489 in contig AE000782_GR.
KEGGafu:AF1489.
NMPDRfig|224325.1.peg.1479.
TIGRAF_1489.

Phylogenomic databases

HOGENOMHBG733885.
OMAVADDPSM.
ProtClustDBCLSK2746922.

Enzyme and pathway databases

BioCycAFUL224325:AF_1489-MONOMER.

Family and domain databases

InterProIPR001450. 4Fe4S-bd_dom.
IPR017896. 4Fe4S_Fe-S-bd.
IPR017900. 4Fe4S_Fe_S_CS.
IPR017721. Indolepyruvate_Fd_OxRdtase_asu.
IPR002880. Pyrv_Fd/Flavodoxin_OxRdtase_N.
IPR011766. TPP_enzyme-bd_C.
IPR009014. Transketo_C/Pyr-ferredox_oxred.
IPR015941. Transketolase-like_C.
[Graphical view]
Gene3DG3DSA:3.40.50.920. Transketo_C_like. 1 hit.
KOK00179.
PfamPF00037. Fer4. 1 hit.
PF01855. POR_N. 1 hit.
PF02775. TPP_enzyme_C. 1 hit.
[Graphical view]
SUPFAMSSF52922. Transketo_C_like. 1 hit.
TIGRFAMsTIGR03336. IOR_alpha. 1 hit.
PROSITEPS00198. 4FE4S_FER_1. 1 hit.
PS51379. 4FE4S_FER_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameIORA_ARCFU
AccessionPrimary (citable) accession number: O28783
Entry history
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: January 1, 1998
Last modified: November 16, 2011
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents