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O28604

- O28604_ARCFU

UniProt

O28604 - O28604_ARCFU

Protein
Submitted name:

Adenylylsulfate reductase, subunit B (AprB)

Gene

AF_1669

Organism
Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 87 (01 Oct 2014)
      Sequence version 1 (01 Jan 1998)
      Previous versions | rss
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    Functioni

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi3 – 31Iron-sulfur(4Fe-4S) 1Imported
    Metal bindingi10 – 101Iron-sulfur(4Fe-4S) 2Imported
    Metal bindingi11 – 111Iron-sulfur(4Fe-4S) 2Imported
    Metal bindingi13 – 131Iron-sulfur(4Fe-4S) 2Imported
    Metal bindingi21 – 211Iron-sulfur(4Fe-4S) 2Imported
    Metal bindingi25 – 251Iron-sulfur(4Fe-4S) 1Imported
    Metal bindingi47 – 471Iron-sulfur(4Fe-4S) 1Imported
    Sitei48 – 481Important for catalytic activityImported
    Metal bindingi50 – 501Iron-sulfur(4Fe-4S) 1Imported
    Metal bindingi53 – 531Iron-sulfur(4Fe-4S) 1Imported
    Metal bindingi57 – 571Iron-sulfur(4Fe-4S) 2Imported
    Metal bindingi58 – 581Iron-sulfur(4Fe-4S) 2Imported
    Metal bindingi62 – 621Iron-sulfur(4Fe-4S) 2Imported

    GO - Molecular functioni

    1. 4 iron, 4 sulfur cluster binding Source: UniProtKB-KW
    2. metal ion binding Source: UniProtKB-KW

    Keywords - Ligandi

    4Fe-4SUniRule annotation, Iron, Iron-sulfur, Metal-binding

    Enzyme and pathway databases

    BioCyciAFUL224325:GJBC-1703-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Adenylylsulfate reductase, subunit B (AprB)Imported
    Gene namesi
    Ordered Locus Names:AF_1669Imported
    OrganismiArchaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)Imported
    Taxonomic identifieri224325 [NCBI]
    Taxonomic lineageiArchaeaEuryarchaeotaArchaeoglobiArchaeoglobalesArchaeoglobaceaeArchaeoglobus
    ProteomesiUP000002199: Chromosome

    Interactioni

    Protein-protein interaction databases

    STRINGi224325.AF1669.

    Structurei

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    1JNRX-ray1.60B/D1-150[»]
    1JNZX-ray2.50B/D1-150[»]
    2FJAX-ray2.00B/D1-150[»]
    2FJBX-ray1.70B/D1-150[»]
    2FJDX-ray1.84B/D1-150[»]
    2FJEX-ray1.80B/D1-150[»]
    ProteinModelPortaliO28604.
    SMRiO28604. Positions 2-150.
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiO28604.

    Family & Domainsi

    Phylogenomic databases

    eggNOGiCOG1146.
    KOiK00395.
    OMAiAYNQEPD.

    Family and domain databases

    InterProiIPR001450. 4Fe4S-bd_dom.
    IPR017896. 4Fe4S_Fe-S-bd.
    IPR017900. 4Fe4S_Fe_S_CS.
    IPR011802. AprB.
    IPR022738. AprB_C.
    [Graphical view]
    PfamiPF12139. APS-reductase_C. 1 hit.
    PF00037. Fer4. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR02060. aprB. 1 hit.
    PROSITEiPS00198. 4FE4S_FER_1. 1 hit.
    PS51379. 4FE4S_FER_2. 2 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    O28604-1 [UniParc]FASTAAdd to Basket

    « Hide

    MPSFVNPEKC DGCKALERTA CEYICPNDLM TLDKEKMKAY NREPDMCWEC    50
    YSCVKMCPQG AIDVRGYVDY SPLGGACVPM RGTSDIMWTV KYRNGKVLRF 100
    KFAIRTTPWG SIQPFEGFPE PTEEALKSEL LAGEPEIIGT SEFPQVKKKA 150
    Length:150
    Mass (Da):16,938
    Last modified:January 1, 1998 - v1
    Checksum:i5136A55608ADC183
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE000782 Genomic DNA. Translation: AAB89580.1.
    PIRiD69458.
    RefSeqiNP_070497.1. NC_000917.1.

    Genome annotation databases

    EnsemblBacteriaiAAB89580; AAB89580; AF_1669.
    GeneIDi1484892.
    KEGGiafu:AF1669.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE000782 Genomic DNA. Translation: AAB89580.1 .
    PIRi D69458.
    RefSeqi NP_070497.1. NC_000917.1.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    1JNR X-ray 1.60 B/D 1-150 [» ]
    1JNZ X-ray 2.50 B/D 1-150 [» ]
    2FJA X-ray 2.00 B/D 1-150 [» ]
    2FJB X-ray 1.70 B/D 1-150 [» ]
    2FJD X-ray 1.84 B/D 1-150 [» ]
    2FJE X-ray 1.80 B/D 1-150 [» ]
    ProteinModelPortali O28604.
    SMRi O28604. Positions 2-150.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 224325.AF1669.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAB89580 ; AAB89580 ; AF_1669 .
    GeneIDi 1484892.
    KEGGi afu:AF1669.

    Phylogenomic databases

    eggNOGi COG1146.
    KOi K00395.
    OMAi AYNQEPD.

    Enzyme and pathway databases

    BioCyci AFUL224325:GJBC-1703-MONOMER.

    Miscellaneous databases

    EvolutionaryTracei O28604.

    Family and domain databases

    InterProi IPR001450. 4Fe4S-bd_dom.
    IPR017896. 4Fe4S_Fe-S-bd.
    IPR017900. 4Fe4S_Fe_S_CS.
    IPR011802. AprB.
    IPR022738. AprB_C.
    [Graphical view ]
    Pfami PF12139. APS-reductase_C. 1 hit.
    PF00037. Fer4. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR02060. aprB. 1 hit.
    PROSITEi PS00198. 4FE4S_FER_1. 1 hit.
    PS51379. 4FE4S_FER_2. 2 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The complete genome sequence of the hyperthermophilic, sulphate-reducing archaeon Archaeoglobus fulgidus."
      Klenk H.-P., Clayton R.A., Tomb J.-F., White O., Nelson K.E., Ketchum K.A., Dodson R.J., Gwinn M.L., Hickey E.K., Peterson J.D., Richardson D.L., Kerlavage A.R., Graham D.E., Kyrpides N.C., Fleischmann R.D., Quackenbush J., Lee N.H., Sutton G.G.
      , Gill S.R., Kirkness E.F., Dougherty B.A., McKenney K., Adams M.D., Loftus B.J., Peterson S.N., Reich C.I., McNeil L.K., Badger J.H., Glodek A., Zhou L., Overbeek R., Gocayne J.D., Weidman J.F., McDonald L.A., Utterback T.R., Cotton M.D., Spriggs T., Artiach P., Kaine B.P., Sykes S.M., Sadow P.W., D'Andrea K.P., Bowman C., Fujii C., Garland S.A., Mason T.M., Olsen G.J., Fraser C.M., Smith H.O., Woese C.R., Venter J.C.
      Nature 390:364-370(1997) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126Imported.
    2. "Structure of adenylylsulfate reductase from the hyperthermophilic Archaeoglobus fulgidus at 1.6-A resolution."
      Fritz G., Roth A., Schiffer A., Buchert T., Bourenkov G., Bartunik H.D., Huber H., Stetter K.O., Kroneck P.M., Ermler U.
      Proc. Natl. Acad. Sci. U.S.A. 99:1836-1841(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (1.60 ANGSTROMS) IN COMPLEX WITH IRON-SULFUR(4FE-4S), ACTIVE SITE.
    3. "Reaction mechanism of the iron-sulfur flavoenzyme adenosine-5'-phosphosulfate reductase based on the structural characterization of different enzymatic states."
      Schiffer A., Fritz G., Kroneck P.M., Ermler U.
      Biochemistry 45:2960-2967(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (1.70 ANGSTROMS) IN COMPLEX WITH IRON-SULFUR(4FE-4S).

    Entry informationi

    Entry nameiO28604_ARCFU
    AccessioniPrimary (citable) accession number: O28604
    Entry historyi
    Integrated into UniProtKB/TrEMBL: January 1, 1998
    Last sequence update: January 1, 1998
    Last modified: October 1, 2014
    This is version 87 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    3D-structureImported, Complete proteome, Reference proteomeImported

    External Data

    Dasty 3