Reviewed,
UniProtKB/Swiss-Prot O28580 (PUR5_ARCFU)
Last modified
November 3, 2009.
Version 55.
History...
Clusters with 100%,
90%,
50% identity |
Documents (2) |
Third-party data |
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Names and origin
| Protein names | Recommended name: Phosphoribosylformylglycinamidine cyclo-ligase EC=6.3.3.1 Alternative name(s): AIRS Phosphoribosyl-aminoimidazole synthetase AIR synthase | ||||
| Gene names |
| ||||
| Organism | Archaeoglobus fulgidus [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 2234 [NCBI] | ||||
| Taxonomic lineage | Archaea › Euryarchaeota › Archaeoglobi › Archaeoglobales › Archaeoglobaceae › Archaeoglobus |
Protein attributes
| Sequence length | 329 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Catalytic activity | ATP + 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine = ADP + phosphate + 5-amino-1-(5-phospho-D-ribosyl)imidazole. HAMAP MF_00741 |
| Pathway | Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole from N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide: step 2/2. HAMAP MF_00741 |
| Subcellular location | Cytoplasm By similarity. |
| Sequence similarities | Belongs to the AIR synthase family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Purine biosynthesis |
| Cellular component | Cytoplasm |
| Ligand | ATP-binding Nucleotide-binding |
| Molecular function | Ligase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | 'de novo' IMP biosynthetic process Inferred from electronic annotation. Source: InterPro |
| Cellular component | cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | ATP binding Inferred from electronic annotation. Source: UniProtKB-KW phosphoribosylformylglycinamidine cyclo-ligase activityInferred from electronic annotation. Source: HAMAP |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||
Molecule processing | |||||||
|---|---|---|---|---|---|---|---|
| Chain | 1 – 329 | 329 | Phosphoribosylformylglycinamidine cyclo-ligase HAMAP MF_00741 | PRO_0000148279 | |||
Sequences
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References
| [1] | "The complete genome sequence of the hyperthermophilic, sulphate-reducing archaeon Archaeoglobus fulgidus." Klenk H.-P., Clayton R.A., Tomb J.-F., White O., Nelson K.E., Ketchum K.A., Dodson R.J., Gwinn M.L., Hickey E.K., Peterson J.D., Richardson D.L., Kerlavage A.R., Graham D.E., Kyrpides N.C., Fleischmann R.D., Quackenbush J., Lee N.H., Sutton G.G. Venter J.C.Nature 390:364-370(1997) [PubMed: 9389475] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126. |
Cross-references
Sequence databases | |
|---|---|
| AE000782 Genomic DNA. Translation: AAB89555.1. | |
| PIR | D69461. |
| RefSeq | NP_070521.1. |
3D structure databases | |
| HSSP | HSSP built from PDB template 1CLI based on UniProtKB P08178. |
| ModBase | Search... |
Genome annotation databases | |
| GeneID | 1484916. |
| GenomeReviews | Gene locus AF_1693 in contig AE000782_GR. |
| KEGG | afu:AF1693. |
| NMPDR | fig|224325.1.peg.1682. |
| TIGR | AF_1693. |
Phylogenomic databases | |
| HOGENOM | O28580. |
| OMA | VHGLAHI. |
Enzyme and pathway databases | |
| BioCyc | AFUL224325:AF_1693-MON. |
| BRENDA | 6.3.3.1. 7576. |
Family and domain databases | |
| HAMAP | MF_00741. [Tree] |
| InterPro | IPR000728. AIR_synth. IPR010918. AIR_synth_C. IPR004733. PurM_cligase. [Graphical view] |
| Pfam | PF00586. AIRS. 1 hit. PF02769. AIRS_C. 1 hit. [Graphical view] |
| TIGRFAMs | TIGR00878. purM. 1 hit. |
| ProtoNet | Search... |
Entry information
| Entry name | PUR5_ARCFU | ||||||||
| Accession | Primary (citable) accession number: O28580 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

Clusters with


