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O28555

- ILVH_ARCFU

UniProt

O28555 - ILVH_ARCFU

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Protein

Probable acetolactate synthase small subunit

Gene
ilvH, ilvN, AF_1719
Organism
Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

2 pyruvate = 2-acetolactate + CO2.

Pathwayi

GO - Molecular functioni

  1. acetolactate synthase activity Source: UniProtKB-EC
  2. amino acid binding Source: InterPro

GO - Biological processi

  1. isoleucine biosynthetic process Source: UniProtKB-UniPathway
  2. valine biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Transferase

Keywords - Biological processi

Amino-acid biosynthesis, Branched-chain amino acid biosynthesis

Enzyme and pathway databases

BioCyciAFUL224325:GJBC-1754-MONOMER.
RETL1328306-WGS:GSTH-2829-MONOMER.
UniPathwayiUPA00047; UER00055.
UPA00049; UER00059.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable acetolactate synthase small subunit (EC:2.2.1.6)
Alternative name(s):
Acetohydroxy-acid synthase small subunit
Short name:
AHAS
Short name:
ALS
Gene namesi
Name:ilvH
Synonyms:ilvN
Ordered Locus Names:AF_1719
OrganismiArchaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)
Taxonomic identifieri224325 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaArchaeoglobiArchaeoglobalesArchaeoglobaceaeArchaeoglobus
ProteomesiUP000002199: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 159159Probable acetolactate synthase small subunitPRO_0000151422Add
BLAST

Interactioni

Subunit structurei

Dimer of large and small chains By similarity.

Protein-protein interaction databases

STRINGi224325.AF1719.

Structurei

3D structure databases

ProteinModelPortaliO28555.
SMRiO28555. Positions 1-157.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini4 – 7875ACTAdd
BLAST

Sequence similaritiesi

Contains 1 ACT domain.

Phylogenomic databases

eggNOGiCOG0440.
KOiK01653.
OMAiRGAKGWK.

Family and domain databases

InterProiIPR004789. Acetalactate_synth_ssu.
IPR019455. Acetolactate_synth_ssu_C.
IPR002912. ACT_dom.
[Graphical view]
PfamiPF01842. ACT. 1 hit.
PF10369. ALS_ss_C. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00119. acolac_sm. 1 hit.
PROSITEiPS51671. ACT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O28555-1 [UniParc]FASTAAdd to Basket

« Hide

MKHTIAVLVE NKPGVLARVA GLFRRRGFNI ESLTVGTTER DDLSRMTIVV    50
EGDDKVVEQV IKQLNKLIET IKVSEITESS VERELCLIRV HAPPEKRGEI 100
VELTNIFRAR IVDVSRDSFI IEVTGDEDKV SAFIDLMRQY GIKELARTGK 150
VAMVRGNKK 159
Length:159
Mass (Da):17,933
Last modified:January 1, 1998 - v1
Checksum:i5D5EE5741294774F
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE000782 Genomic DNA. Translation: AAB89532.1.
PIRiF69464.
RefSeqiNP_070547.1. NC_000917.1.

Genome annotation databases

EnsemblBacteriaiAAB89532; AAB89532; AF_1719.
GeneIDi1484942.
KEGGiafu:AF1719.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE000782 Genomic DNA. Translation: AAB89532.1 .
PIRi F69464.
RefSeqi NP_070547.1. NC_000917.1.

3D structure databases

ProteinModelPortali O28555.
SMRi O28555. Positions 1-157.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 224325.AF1719.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAB89532 ; AAB89532 ; AF_1719 .
GeneIDi 1484942.
KEGGi afu:AF1719.

Phylogenomic databases

eggNOGi COG0440.
KOi K01653.
OMAi RGAKGWK.

Enzyme and pathway databases

UniPathwayi UPA00047 ; UER00055 .
UPA00049 ; UER00059 .
BioCyci AFUL224325:GJBC-1754-MONOMER.
RETL1328306-WGS:GSTH-2829-MONOMER.

Family and domain databases

InterProi IPR004789. Acetalactate_synth_ssu.
IPR019455. Acetolactate_synth_ssu_C.
IPR002912. ACT_dom.
[Graphical view ]
Pfami PF01842. ACT. 1 hit.
PF10369. ALS_ss_C. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00119. acolac_sm. 1 hit.
PROSITEi PS51671. ACT. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The complete genome sequence of the hyperthermophilic, sulphate-reducing archaeon Archaeoglobus fulgidus."
    Klenk H.-P., Clayton R.A., Tomb J.-F., White O., Nelson K.E., Ketchum K.A., Dodson R.J., Gwinn M.L., Hickey E.K., Peterson J.D., Richardson D.L., Kerlavage A.R., Graham D.E., Kyrpides N.C., Fleischmann R.D., Quackenbush J., Lee N.H., Sutton G.G.
    , Gill S.R., Kirkness E.F., Dougherty B.A., McKenney K., Adams M.D., Loftus B.J., Peterson S.N., Reich C.I., McNeil L.K., Badger J.H., Glodek A., Zhou L., Overbeek R., Gocayne J.D., Weidman J.F., McDonald L.A., Utterback T.R., Cotton M.D., Spriggs T., Artiach P., Kaine B.P., Sykes S.M., Sadow P.W., D'Andrea K.P., Bowman C., Fujii C., Garland S.A., Mason T.M., Olsen G.J., Fraser C.M., Smith H.O., Woese C.R., Venter J.C.
    Nature 390:364-370(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126.

Entry informationi

Entry nameiILVH_ARCFU
AccessioniPrimary (citable) accession number: O28555
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: January 1, 1998
Last modified: July 9, 2014
This is version 84 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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