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Protein
Submitted name:

Myo-inositol-1-phosphate synthase (Ino1)

Gene

AF_1794

Organism
Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei99NAD; via carbonyl oxygenCombined sources1
Binding sitei185NADCombined sources1
Binding sitei199NADCombined sources1
Binding sitei228NADCombined sources1
Binding sitei261NADCombined sources1
Binding sitei274NADCombined sources1
Binding sitei332NADCombined sources1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi10 – 12NADCombined sources3
Nucleotide bindingi57 – 59NADCombined sources3
Nucleotide bindingi148 – 150NADCombined sources3

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Ligandi

NADCombined sources, Nucleotide-bindingCombined sources

Enzyme and pathway databases

BioCyciMetaCyc:MONOMER-5064.

Names & Taxonomyi

Protein namesi
Submitted name:
Myo-inositol-1-phosphate synthase (Ino1)Imported
Gene namesi
Ordered Locus Names:AF_1794Imported
OrganismiArchaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)Imported
Taxonomic identifieri224325 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaArchaeoglobiArchaeoglobalesArchaeoglobaceaeArchaeoglobus
Proteomesi
  • UP000002199 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei325 – 348HelicalSequence analysisAdd BLAST24

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Interactioni

Protein-protein interaction databases

STRINGi224325.AF1794.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1U1IX-ray1.90A/B/C/D1-392[»]
3QVSX-ray1.70A1-392[»]
3QVTX-ray2.00A1-392[»]
3QVWX-ray2.00A1-392[»]
3QVXX-ray1.90A1-392[»]
3QW2X-ray2.59A/B/C/D1-392[»]
ProteinModelPortaliO28480.
SMRiO28480.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiO28480.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini229 – 332Inos-1-P_synthInterPro annotationAdd BLAST104

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiarCOG04213. Archaea.
COG1260. LUCA.
KOiK01858.
OMAiHAGNDGK.

Family and domain databases

Gene3Di3.40.50.720. 2 hits.
InterProiIPR002587. Myo-inos-1-P_Synthase.
IPR013021. Myo-inos-1-P_Synthase_GAPDH.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PANTHERiPTHR11510. PTHR11510. 1 hit.
PfamiPF01658. Inos-1-P_synth. 1 hit.
PF07994. NAD_binding_5. 1 hit.
[Graphical view]
PIRSFiPIRSF015578. Myoinos-ppht_syn. 1 hit.
SUPFAMiSSF51735. SSF51735. 2 hits.

Sequencei

Sequence statusi: Complete.

O28480-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKVWLVGAYG IVSTTAMVGA RAIERGIAPK IGLVSELPHF EGIEKYAPFS
60 70 80 90 100
FEFGGHEIRL LSNAYEAAKE HWELNRHFDR EILEAVKSDL EGIVARKGTA
110 120 130 140 150
LNCGSGIKEL GDIKTLEGEG LSLAEMVSRI EEDIKSFADD ETVVINVAST
160 170 180 190 200
EPLPNYSEEY HGSLEGFERM IDEDRKEYAS ASMLYAYAAL KLGLPYANFT
210 220 230 240 250
PSPGSAIPAL KELAEKKGVP HAGNDGKTGE TLVKTTLAPM FAYRNMEVVG
260 270 280 290 300
WMSYNILGDY DGKVLSARDN KESKVLSKDK VLEKMLGYSP YSITEIQYFP
310 320 330 340 350
SLVDNKTAFD FVHFKGFLGK LMKFYFIWDA IDAIVAAPLI LDIARFLLFA
360 370 380 390
KKKGVKGVVK EMAFFFKSPM DTNVINTHEQ FVVLKEWYSN LK
Length:392
Mass (Da):43,713
Last modified:January 1, 1998 - v1
Checksum:i387B0AFA946EBFDB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000782 Genomic DNA. Translation: AAB89456.1.
PIRiA69474.
RefSeqiWP_010879290.1. NC_000917.1.

Genome annotation databases

EnsemblBacteriaiAAB89456; AAB89456; AF_1794.
GeneIDi24795537.
KEGGiafu:AF_1794.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000782 Genomic DNA. Translation: AAB89456.1.
PIRiA69474.
RefSeqiWP_010879290.1. NC_000917.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1U1IX-ray1.90A/B/C/D1-392[»]
3QVSX-ray1.70A1-392[»]
3QVTX-ray2.00A1-392[»]
3QVWX-ray2.00A1-392[»]
3QVXX-ray1.90A1-392[»]
3QW2X-ray2.59A/B/C/D1-392[»]
ProteinModelPortaliO28480.
SMRiO28480.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi224325.AF1794.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAB89456; AAB89456; AF_1794.
GeneIDi24795537.
KEGGiafu:AF_1794.

Phylogenomic databases

eggNOGiarCOG04213. Archaea.
COG1260. LUCA.
KOiK01858.
OMAiHAGNDGK.

Enzyme and pathway databases

BioCyciMetaCyc:MONOMER-5064.

Miscellaneous databases

EvolutionaryTraceiO28480.

Family and domain databases

Gene3Di3.40.50.720. 2 hits.
InterProiIPR002587. Myo-inos-1-P_Synthase.
IPR013021. Myo-inos-1-P_Synthase_GAPDH.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PANTHERiPTHR11510. PTHR11510. 1 hit.
PfamiPF01658. Inos-1-P_synth. 1 hit.
PF07994. NAD_binding_5. 1 hit.
[Graphical view]
PIRSFiPIRSF015578. Myoinos-ppht_syn. 1 hit.
SUPFAMiSSF51735. SSF51735. 2 hits.
ProtoNetiSearch...

Entry informationi

Entry nameiO28480_ARCFU
AccessioniPrimary (citable) accession number: O28480
Entry historyi
Integrated into UniProtKB/TrEMBL: January 1, 1998
Last sequence update: January 1, 1998
Last modified: November 2, 2016
This is version 97 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.