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Protein

Ribonuclease P protein component 1

Gene

rnp1

Organism
Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

Catalytic activityi

Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionEndonuclease, Hydrolase, Nuclease
Biological processtRNA processing

Enzyme and pathway databases

BRENDAi3.1.26.5. 414.

Names & Taxonomyi

Protein namesi
Recommended name:
Ribonuclease P protein component 1UniRule annotation (EC:3.1.26.5UniRule annotation)
Short name:
RNase P component 1UniRule annotation
Alternative name(s):
Rpp29UniRule annotation
aRpp29
Gene namesi
Name:rnp1UniRule annotation
Ordered Locus Names:AF_1917
OrganismiArchaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)
Taxonomic identifieri224325 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaArchaeoglobiArchaeoglobalesArchaeoglobaceaeArchaeoglobus
Proteomesi
  • UP000002199 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001284251 – 102Ribonuclease P protein component 1Add BLAST102

Proteomic databases

PRIDEiO28362.

Interactioni

Subunit structurei

Consists of a catalytic RNA component and at least 4-5 protein subunits.UniRule annotation

Protein-protein interaction databases

STRINGi224325.AF1917.

Structurei

Secondary structure

1102
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi6 – 12Combined sources7
Beta strandi19 – 24Combined sources6
Helixi28 – 30Combined sources3
Beta strandi34 – 40Combined sources7
Beta strandi42 – 57Combined sources16
Beta strandi62 – 67Combined sources6
Beta strandi70 – 75Combined sources6
Helixi76 – 78Combined sources3
Helixi83 – 96Combined sources14
Turni97 – 99Combined sources3

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1PC0NMR-A17-77[»]
1TS9X-ray1.70A1-102[»]
1TSFX-ray1.70A1-102[»]
DisProtiDP00382.
ProteinModelPortaliO28362.
SMRiO28362.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiO28362.

Family & Domainsi

Sequence similaritiesi

Belongs to the eukaryotic/archaeal RNase P protein component 1 family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG00784. Archaea.
COG1588. LUCA.
KOiK03538.
OMAiDLINFRP.
OrthoDBiPOG093Z0M9M.

Family and domain databases

Gene3Di2.30.30.210. 1 hit.
HAMAPiMF_00754. RNase_P_1. 1 hit.
InterProiView protein in InterPro
IPR002730. RNase_P/MRP_p29.
IPR023538. RNP1.
IPR023534. Rof/RNase_P-like.
PfamiView protein in Pfam
PF01868. UPF0086. 1 hit.
SMARTiView protein in SMART
SM00538. POP4. 1 hit.
SUPFAMiSSF101744. SSF101744. 1 hit.

Sequencei

Sequence statusi: Complete.

O28362-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRGRLQGVEL IARDWIGLMV EVVESPNHSE VGIKGEVVDE TQNTLKIMTE
60 70 80 90 100
KGLKVVAKRG RTFRVWYKGK IMRIKGDLIN FRPEDRIKRG LMMLKRAKGV

WI
Length:102
Mass (Da):11,806
Last modified:January 1, 1998 - v1
Checksum:iDF427B08A4543567
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000782 Genomic DNA. Translation: AAB89336.1.
PIRiD69489.
RefSeqiWP_010879410.1. NC_000917.1.

Genome annotation databases

EnsemblBacteriaiAAB89336; AAB89336; AF_1917.
GeneIDi24795661.
KEGGiafu:AF_1917.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiRNP1_ARCFU
AccessioniPrimary (citable) accession number: O28362
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: January 1, 1998
Last modified: March 15, 2017
This is version 107 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families
  3. Uncharacterized protein families (UPF)
    List of uncharacterized protein family (UPF) entries