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O28234 (PSD_ARCFU) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 62. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphatidylserine decarboxylase proenzyme
EC=4.1.1.65

Cleaved into the following 2 chains:

  1. Phosphatidylserine decarboxylase alpha chain
  2. Phosphatidylserine decarboxylase beta chain
Gene names
Name:psd
Ordered Locus Names:AF_2045
OrganismArchaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)
Taxonomic identifier224325 [NCBI]
Taxonomic lineageArchaea › Euryarchaeota › Archaeoglobi › Archaeoglobales › Archaeoglobaceae › Archaeoglobus

Protein attributes

Sequence length195 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Phosphatidyl-L-serine = phosphatidylethanolamine + CO2. HAMAP MF_00664

Cofactor

Pyruvoyl group By similarity. HAMAP MF_00664

Pathway

Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from CDP-diacylglycerol: step 2/2. HAMAP MF_00664

Sequence similarities

Belongs to the phosphatidylserine decarboxylase family. Type 3 subfamily.

Ontologies

Keywords
   Biological processPhospholipid biosynthesis
   LigandPyruvate
   Molecular functionDecarboxylase
Lyase
   PTMZymogen
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological processphosphatidylethanolamine biosynthetic process

Inferred from electronic annotation. Source: InterPro

   Molecular functioncofactor binding

Inferred from electronic annotation. Source: InterPro

phosphatidylserine decarboxylase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 158158Phosphatidylserine decarboxylase beta chain By similarity
PRO_0000029819
Chain159 – 19537Phosphatidylserine decarboxylase alpha chain By similarity
PRO_0000029820

Sites

Site158 – 1592Cleavage (non-hydrolytic) By similarity

Amino acid modifications

Modified residue1591Pyruvic acid (Ser) By similarity

Sequences

Sequence LengthMass (Da)Tools
O28234 [UniParc].

Last modified January 1, 1998. Version 1.
Checksum: 3FFBE5984581E5C3

FASTA19521,558
        10         20         30         40         50         60 
MIERSGYGII AASLLLSAVA YLLHPLISAL FVGFALFTAY FFRDPERKIG EGVVSPADGR 

        70         80         90        100        110        120 
IDYLEGRRLE IFMSPFDCHI NRAPWGGKVL SVKFIEGSTP PAFIRKSGVR TNEILIETEH 

       130        140        150        160        170        180 
GVFRVLQMAG IFARRIVSYV SEGDVVKKGQ KIGMIRFGSR VVLEVPEGFR FVRGVGEKVK 

       190 
AGETVALRDE SFQGS

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE000782 Genomic DNA. Translation: AAB89201.1.
PIRD69505.
RefSeqNP_070869.1. NC_000917.1.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1485272.
GenomeReviewsGene locus AF_2045 in contig AE000782_GR.
KEGGafu:AF2045.
NMPDRfig|224325.1.peg.2030.
TIGRAF_2045.

Phylogenomic databases

HOGENOMHBG541103.
OMANERVVWH.
PhylomeDBO28234.
ProtClustDBPRK05305.

Enzyme and pathway databases

BioCycAFUL224325:AF_2045-MONOMER.

Family and domain databases

HAMAPMF_00664. PS_decarb_type3.
[Tree]
InterProIPR003817. PS_Dcarbxylase.
IPR004428. PtdSer_deCO2ase-related.
[Graphical view]
KOK01613.
PfamPF02666. PS_Dcarbxylase. 1 hit.
[Graphical view]
TIGRFAMsTIGR00164. PS_decarb_rel. 1 hit.
ProtoNetSearch...

Entry information

Entry namePSD_ARCFU
AccessionPrimary (citable) accession number: O28234
Entry history
Integrated into UniProtKB/Swiss-Prot: July 3, 2003
Last sequence update: January 1, 1998
Last modified: December 14, 2011
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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