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O28185 (PTH_ARCFU) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 74. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Peptidyl-tRNA hydrolase
Short name=PTH
EC=3.1.1.29
Gene names
Name:pth
Ordered Locus Names:AF_2095
OrganismArchaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)
Taxonomic identifier224325 [NCBI]
Taxonomic lineageArchaea › Euryarchaeota › Archaeoglobi › Archaeoglobales › Archaeoglobaceae › Archaeoglobus

Protein attributes

Sequence length115 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis By similarity. HAMAP MF_00628

Catalytic activity

N-substituted aminoacyl-tRNA + H2O = N-substituted amino acid + tRNA. HAMAP MF_00628

Subcellular location

Cytoplasm By similarity HAMAP MF_00628.

Sequence similarities

Belongs to the PTH2 family.

Ontologies

Keywords
   Cellular componentCytoplasm
   Molecular functionHydrolase
   Technical term3D-structure
Complete proteome
Reference proteome
Gene Ontology (GO)
   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionaminoacyl-tRNA hydrolase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 115115Peptidyl-tRNA hydrolase HAMAP MF_00628
PRO_0000120288

Secondary structure

1 ................... 115
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
O28185 [UniParc].

Last modified January 1, 1998. Version 1.
Checksum: 4DEEC200CF881489

FASTA11512,487
        10         20         30         40         50         60 
MTLKQVIVVR DDLKLSRGKL AVQVAHAAII GYLKSDSSLR RKWLDEGQKK VVLKVKSLEE 

        70         80         90        100        110 
LLGIKHKAES LGLVTGLVQD AGLTEVPPGT ITAVVIGPDE ERKIDKVTGN LPLLK

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE000782 Genomic DNA. Translation: AAB89160.1.
PIRG69511.
RefSeqNP_070920.1. NC_000917.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
1RZWNMR-A1-115[»]
3ERJX-ray1.80A/B1-115[»]
ProteinModelPortalO28185.
SMRO28185. Positions 1-115.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1485324.
GenomeReviewsGene locus AF_2095 in contig AE000782_GR.
KEGGafu:AF2095.
NMPDRfig|224325.1.peg.2081.
TIGRAF_2095.

Phylogenomic databases

HOGENOMHBG526257.
OMAKSLVMEY.
PhylomeDBO28185.
ProtClustDBPRK04322.

Enzyme and pathway databases

BioCycAFUL224325:AF_2095-MONOMER.

Family and domain databases

HAMAPMF_00628. Pept_tRNA_hydro_arch.
[Tree]
InterProIPR023476. Pep_tRNA_hydro_II_dom.
IPR002833. Pep_tRNA_hydro_PTH2.
[Graphical view]
Gene3DG3DSA:3.40.1490.10. G3DSA:3.40.1490.10. 1 hit.
KOK04794.
PANTHERPTHR12649:SF6. PTHR12649:SF6. 1 hit.
PfamPF01981. PTH2. 1 hit.
[Graphical view]
SUPFAMSSF102462. SSF102462. 1 hit.
TIGRFAMsTIGR00283. Arch_pth2. 1 hit.
ProtoNetSearch...

Entry information

Entry namePTH_ARCFU
AccessionPrimary (citable) accession number: O28185
Entry history
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: January 1, 1998
Last modified: December 14, 2011
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

SIMILARITY comments

Index of protein domains and families

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