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Protein

Thermosome subunit alpha

Gene

thsA

Organism
Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Molecular chaperone; binds unfolded polypeptides in vitro, and has a weak ATPase activity.By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperone
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Thermosome subunit alpha
Alternative name(s):
Chaperonin subunit alpha
Thermosome subunit 1
Gene namesi
Name:thsA
Ordered Locus Names:AF_2238
OrganismiArchaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)
Taxonomic identifieri224325 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaArchaeoglobiArchaeoglobalesArchaeoglobaceaeArchaeoglobus
Proteomesi
  • UP000002199 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001283811 – 545Thermosome subunit alphaAdd BLAST545

Proteomic databases

PRIDEiO28045

Interactioni

Subunit structurei

Forms a Heterooligomeric complex of two stacked eight-membered rings.By similarity

GO - Molecular functioni

Protein-protein interaction databases

STRINGi224325.AF2238

Structurei

3D structure databases

ProteinModelPortaliO28045
SMRiO28045
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the TCP-1 chaperonin family.Curated

Phylogenomic databases

eggNOGiarCOG01257 Archaea
COG0459 LUCA
KOiK22447
OMAiYATDEYG
OrthoDBiPOG093Z02BT

Family and domain databases

CDDicd03343 cpn60, 1 hit
Gene3Di1.10.560.10, 2 hits
3.30.260.10, 2 hits
3.50.7.10, 1 hit
InterProiView protein in InterPro
IPR017998 Chaperone_TCP-1
IPR002194 Chaperonin_TCP-1_CS
IPR002423 Cpn60/TCP-1
IPR027409 GroEL-like_apical_dom_sf
IPR027413 GROEL-like_equatorial_sf
IPR027410 TCP-1-like_intermed_sf
IPR012714 Thermosome_arc
PfamiView protein in Pfam
PF00118 Cpn60_TCP1, 1 hit
PRINTSiPR00304 TCOMPLEXTCP1
SUPFAMiSSF48592 SSF48592, 2 hits
SSF52029 SSF52029, 1 hit
SSF54849 SSF54849, 2 hits
TIGRFAMsiTIGR02339 thermosome_arch, 1 hit
PROSITEiView protein in PROSITE
PS00750 TCP1_1, 1 hit
PS00751 TCP1_2, 1 hit
PS00995 TCP1_3, 1 hit

Sequencei

Sequence statusi: Complete.

O28045-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATLQGTPVL ILKEGTQRTV GRDAQRMNIM AARVIAEAVK STLGPKGMDK
60 70 80 90 100
MLVDSLGDVV ITNDGVTILK EMDVEHPAAK MIIEVAKTQD NEVGDGTTTA
110 120 130 140 150
VVLAGELLKK AEELLDQDIH PTVIARGYRM AANKAVEILE SIAMDIDVED
160 170 180 190 200
EETLKKIAAT AITGKHSEYA LDHLSSLVVE AVKRVAEKVD DRYKVDEDNI
210 220 230 240 250
KLEKRQGGSV ADTKLVNGIV IDKEVVHPGM PKRVKNAKIA VLKAALEVKE
260 270 280 290 300
TETDAEIRIT DPDQLMKFIE QEEKMLKEMV DRLAEAGANV VFCQKGIDDL
310 320 330 340 350
AQYYLAKAGI LAVRRVKQSD IEKIAKACGA KIITDLREIT SADLGEAELV
360 370 380 390 400
EERKVGDEKM VFIEGCKNPK AVTILIRGGS EHVVDEVERS LQDAIKVVKT
410 420 430 440 450
ALESGKVVAG GGAPEIEVAL KIRDWAPTLG GREQLAAEAF ASALEVIPRA
460 470 480 490 500
LAENSGLDPI DILVELRKAH EEGKTTYGVD VFSGEVACMK ERGVLEPLKV
510 520 530 540
KTQAITSATE VAIMILRIDD VIAAKGLEKE KGPEGESGGE EDSEE
Length:545
Mass (Da):58,978
Last modified:January 1, 1998 - v1
Checksum:iC774722EE6AA4EE2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000782 Genomic DNA Translation: AAB89014.1
AF035826 Genomic DNA Translation: AAB88860.1
PIRiF69529
RefSeqiWP_010878948.1, NC_000917.1
WP_010879727.1, NC_000917.1

Genome annotation databases

EnsemblBacteriaiAAB89014; AAB89014; AF_2238
GeneIDi24795063
24796000
KEGGiafu:AF_2238

Similar proteinsi

Entry informationi

Entry nameiTHSA_ARCFU
AccessioniPrimary (citable) accession number: O28045
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: January 1, 1998
Last modified: May 23, 2018
This is version 111 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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