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Protein

Translation initiation factor 2 subunit beta

Gene

eif2b

Organism
Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.By similarity

GO - Molecular functioni

Keywordsi

Molecular functionInitiation factor
Biological processProtein biosynthesis

Names & Taxonomyi

Protein namesi
Recommended name:
Translation initiation factor 2 subunit beta
Alternative name(s):
aIF2-beta
eIF-2-beta
Gene namesi
Name:eif2b
Ordered Locus Names:AF_2326
OrganismiArchaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)
Taxonomic identifieri224325 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaArchaeoglobiArchaeoglobalesArchaeoglobaceaeArchaeoglobus
Proteomesi
  • UP000002199 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001374171 – 137Translation initiation factor 2 subunit betaAdd BLAST137

Interactioni

Subunit structurei

Heterotrimer composed of an alpha, a beta and a gamma chain.By similarity

Protein-protein interaction databases

STRINGi224325.AF2326.

Structurei

3D structure databases

ProteinModelPortaliO27958.
SMRiO27958.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the eIF-2-beta/eIF-5 family.Curated

Phylogenomic databases

eggNOGiarCOG01640. Archaea.
COG1601. LUCA.
KOiK03238.
OMAiMLRCDAC.
OrthoDBiPOG093Z0DYX.

Family and domain databases

Gene3Di3.30.30.50. 1 hit.
HAMAPiMF_00232. eIF_2_beta. 1 hit.
InterProiView protein in InterPro
IPR004458. TIF2_bsu_arc.
IPR002735. Transl_init_fac_IF2/IF5.
IPR016189. Transl_init_fac_IF2/IF5_N.
IPR016190. Transl_init_fac_IF2/IF5_Zn-bd.
PfamiView protein in Pfam
PF01873. eIF-5_eIF-2B. 1 hit.
SMARTiView protein in SMART
SM00653. eIF2B_5. 1 hit.
SUPFAMiSSF100966. SSF100966. 1 hit.
SSF75689. SSF75689. 1 hit.
TIGRFAMsiTIGR00311. aIF-2beta. 1 hit.

Sequencei

Sequence statusi: Complete.

O27958-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMRSYEELLE RAFEKLADKD VVRRERFEIP RVSIQREGAR TILKNFSQIA
60 70 80 90 100
KTLNRSEDHL YKYIVKSLGT AGFIDNGRLV LQGKFTESEL QKEVDDYVRL
110 120 130
YVLCRECNSP DTEFIKEERV LMLRCLACGA KHPVRNI
Length:137
Mass (Da):16,088
Last modified:January 1, 1998 - v1
Checksum:i11B962290D144E83
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000782 Genomic DNA. Translation: AAB88931.1.
PIRiF69540.

Genome annotation databases

EnsemblBacteriaiAAB88931; AAB88931; AF_2326.
KEGGiafu:AF_2326.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiIF2B_ARCFU
AccessioniPrimary (citable) accession number: O27958
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: January 1, 1998
Last modified: June 7, 2017
This is version 99 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Translation initiation factors
    List of translation initiation factor entries
  2. SIMILARITY comments
    Index of protein domains and families