O27881 (IORB_METTH) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Indolepyruvate oxidoreductase subunit iorB
Short name=IOR
EC=1.2.7.8

Alternative name(s):
Indolepyruvate ferredoxin oxidoreductase subunit beta

Gene names

Name:	iorB
Ordered Locus Names:	MTH_1853

Organism

Methanobacterium thermoautotrophicum (strain Delta H)

Taxonomic identifier

187420 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Methanobacteria › Methanobacteriales › Methanobacteriaceae › Methanothermobacter

Protein attributes

Sequence length	196 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates By similarity.
Catalytic activity	(Indol-3-yl)pyruvate + CoA + 2 oxidized ferredoxin = S-2-(indol-3-yl)acetyl-CoA + CO2 + 2 reduced ferredoxin + H+.
Subunit structure	Heterodimer of the iorA and iorB subunits.

Ontologies

Keywords
Molecular function	Oxidoreductase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular function	indolepyruvate ferredoxin oxidoreductase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 196	196	Indolepyruvate oxidoreductase subunit iorB		PRO_0000099932

Sequences

	Sequence		Length	Mass (Da)
	O27881 [UniParc]. Last modified January 1, 1998. Version 1. Checksum: CF1A16D8535BD034	FASTA	196	20,948
	10 20 30 40 50 60 MNYNIYVCGV GGQGIIKTSV IIGEAAMKKD INVVMSEIHG MAQRGGSVST EIRIGEVHGS 70 80 90 100 110 120 IIPDGEADLV LAFEPLEAIR ALPKMSEESE VILNTSVIPP FNLMRSPHPY PPLDEIMSTL 130 140 150 160 170 180 EERAGSVRGF NAEEIALKAG HILSLNMVML GAAAATPGFP LESESLISSM RDNLPSRLID 190 VNLRAFRDGF GAAAES

References

[1]

"Complete genome sequence of Methanobacterium thermoautotrophicum deltaH: functional analysis and comparative genomics." Smith D.R., Doucette-Stamm L.A., Deloughery C., Lee H.-M., Dubois J., Aldredge T., Bashirzadeh R., Blakely D., Cook R., Gilbert K., Harrison D., Hoang L., Keagle P., Lumm W., Pothier B., Qiu D., Spadafora R., Vicare R. , Wang Y., Wierzbowski J., Gibson R., Jiwani N., Caruso A., Bush D., Safer H., Patwell D., Prabhakar S., McDougall S., Shimer G., Goyal A., Pietrovski S., Church G.M., Daniels C.J., Mao J.-I., Rice P., Noelling J., Reeve J.N. J. Bacteriol. 179:7135-7155(1997) [PubMed: 9371463] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Delta H.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE000666 Genomic DNA. Translation: AAB86319.1.
PIR	H69114.
RefSeq	NP_276959.1. NC_000916.1.
3D structure databases
ProteinModelPortal	O27881.
ModBase	Search...
Protein-protein interaction databases
STRING	O27881.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1470938.
GenomeReviews	Gene locus MTH_1853 in contig AE000666_GR.
KEGG	mth:MTH1853.
NMPDR	fig|187420.1.peg.1814.
Phylogenomic databases
eggNOG	arNOG09698.
HOGENOM	HBG553299.
OMA	VILSFEP.
ProtClustDB	PRK06853.
Enzyme and pathway databases
BioCyc	MTHE187420:MTH1853-MONOMER.
Family and domain databases
InterPro	IPR017719. Indolepyruvate_Fd_OxRdtase_bsu. IPR019752. Pyrv/ketoisovalerate_OxRed_cat. IPR002869. Pyrv_flavodox_OxRed_cen. [Graphical view]
Gene3D	G3DSA:3.40.920.10. Pyrv_Fd/Flavodoxin_OxRdtase. 1 hit.
KO	K00180.
Pfam	PF01558. POR. 1 hit. [Graphical view]
SUPFAM	SSF53323. Pyrv_Fd/Flavodoxin_OxRdtase. 1 hit.
TIGRFAMs	TIGR03334. IOR_beta. 1 hit.
ProtoNet	Search...

Entry information

Entry name

IORB_METTH

Accession

Primary (citable) accession number: O27881

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2000
Last sequence update:	January 1, 1998
Last modified:	November 16, 2011
This is version 70 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program