Reviewed, UniProtKB/Swiss-Prot O27881 (IORB_METTH)

Names and origin

Protein names

Recommended name:
    Indolepyruvate oxidoreductase subunit iorB
      Short name=IOR
    EC=1.2.7.8
Alternative name(s):
    Indolepyruvate ferredoxin oxidoreductase subunit beta

Gene names

Name:	iorB
Ordered Locus Names:	MTH_1853

Organism

Methanobacterium thermoautotrophicum [Complete proteome] [HAMAP]

Taxonomic identifier

187420 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Methanobacteria › Methanobacteriales › Methanobacteriaceae › Methanothermobacter

Protein attributes

Sequence length	196 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates By similarity.
Catalytic activity	(Indol-3-yl)pyruvate + CoA + 2 oxidized ferredoxin = S-2-(indol-3-yl)acetyl-CoA + CO2 + 2 reduced ferredoxin + H+.
Subunit structure	Heterodimer of the iorA and iorB subunits.

Ontologies

Keywords
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	electron carrier activity Inferred from electronic annotation. Source: InterPro indolepyruvate ferredoxin oxidoreductase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 196	196	Indolepyruvate oxidoreductase subunit iorB		PRO_0000099932

Sequences

	Sequence		Length	Mass (Da)
	O27881-1 [UniParc]. Last modified January 1, 1998. Version 1. Checksum: CF1A16D8535BD034	FASTA	196	20,948
	10 20 30 40 50 60 MNYNIYVCGV GGQGIIKTSV IIGEAAMKKD INVVMSEIHG MAQRGGSVST EIRIGEVHGS 70 80 90 100 110 120 IIPDGEADLV LAFEPLEAIR ALPKMSEESE VILNTSVIPP FNLMRSPHPY PPLDEIMSTL 130 140 150 160 170 180 EERAGSVRGF NAEEIALKAG HILSLNMVML GAAAATPGFP LESESLISSM RDNLPSRLID 190 VNLRAFRDGF GAAAES

References

[1]

"Complete genome sequence of Methanobacterium thermoautotrophicum deltaH: functional analysis and comparative genomics." Smith D.R., Doucette-Stamm L.A., Deloughery C., Lee H.-M., Dubois J., Aldredge T., Bashirzadeh R., Blakely D., Cook R., Gilbert K., Harrison D., Hoang L., Keagle P., Lumm W., Pothier B., Qiu D., Spadafora R., Vicare R. , Wang Y., Wierzbowski J., Gibson R., Jiwani N., Caruso A., Bush D., Safer H., Patwell D., Prabhakar S., McDougall S., Shimer G., Goyal A., Pietrovski S., Church G.M., Daniels C.J., Mao J.-I., Rice P., Noelling J., Reeve J.N. J. Bacteriol. 179:7135-7155(1997) [PubMed: 9371463] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Delta H.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE000666 Genomic DNA. Translation: AAB86319.1.
PIR	H69114.
RefSeq	NP_276959.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	1470938.
GenomeReviews	Gene locus MTH_1853 in contig AE000666_GR.
KEGG	mth:MTH1853.
NMPDR	fig|187420.1.peg.1814.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	O27881.
OMA	O27881. ALRYINY.
Enzyme and pathway databases
BioCyc	MTHE187420:MTH1853-MON.
BRENDA	1.2.7.8. 270.
Family and domain databases
InterPro	IPR017719. Indolepyruvate_Fd_OxRdtase_bsu. IPR019752. Pyrv/ketoisovalerate_OxRed. [Graphical view]
Gene3D	G3DSA:3.40.920.10. Pyrv_Fd/Flavodoxin_OxRdtase. 1 hit.
Pfam	PF01558. POR. 1 hit. [Graphical view]
TIGRFAMs	TIGR03334. IOR_beta. 1 hit.
ProtoNet	Search...

Entry information

Entry name

IORB_METTH

Accession

Primary (citable) accession number: O27881

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2000
Last sequence update:	January 1, 1998
Last modified:	June 16, 2009
This is version 52 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)