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O27875

- DCD_METTH

UniProt

O27875 - DCD_METTH

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Protein

Probable deoxycytidine triphosphate deaminase

Gene

dcd

Organism
Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H) (Methanobacterium thermoautotrophicum)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

dCTP + H2O = dUTP + NH3.

Pathwayi

GO - Molecular functioni

  1. dCTP deaminase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. dUMP biosynthetic process Source: UniProtKB-UniPathway
  2. dUTP biosynthetic process Source: InterPro
  3. pyrimidine ribonucleotide biosynthetic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

Nucleotide metabolism

Enzyme and pathway databases

BioCyciMTHE187420:GJNM-1851-MONOMER.
UniPathwayiUPA00610; UER00665.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable deoxycytidine triphosphate deaminase (EC:3.5.4.13)
Short name:
dCTP deaminase
Gene namesi
Name:dcd
Ordered Locus Names:MTH_1847
OrganismiMethanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H) (Methanobacterium thermoautotrophicum)
Taxonomic identifieri187420 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanobacteriaMethanobacterialesMethanobacteriaceaeMethanothermobacter
ProteomesiUP000005223: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 197197Probable deoxycytidine triphosphate deaminasePRO_0000156032Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi187420.MTH1847.

Structurei

3D structure databases

ProteinModelPortaliO27875.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the dCTP deaminase family.Curated

Phylogenomic databases

eggNOGiCOG0717.
KOiK01494.
OMAiRPGMMIG.

Family and domain databases

Gene3Di2.70.40.10. 1 hit.
HAMAPiMF_00146. dCTP_deaminase.
InterProiIPR011962. dCTP_deam.
IPR029054. dUTPase-like.
IPR008180. dUTPase/dCTP_deaminase.
[Graphical view]
PfamiPF00692. dUTPase. 1 hit.
[Graphical view]
SUPFAMiSSF51283. SSF51283. 1 hit.
TIGRFAMsiTIGR02274. dCTP_deam. 1 hit.

Sequencei

Sequence statusi: Complete.

O27875-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAILSDRDIK RYIEEGLITI DPLDDPERQI QPSSVDLRIG NEFKGFRVIR
60 70 80 90 100
KPCIDPKDPS DIESYMETFH VEDGPFIIHP GEFALATTHE YIALPEDLVA
110 120 130 140 150
RVEGRSSIGR LGITMHVTAG YIDPGFHGRI TLEISNIGKM PVALYPRQRV
160 170 180 190
CQIVFETMTS PAERPYGHPS RDSKYIGQTR PQTSRIKDDY EIRNSRL
Length:197
Mass (Da):22,427
Last modified:December 1, 2000 - v2
Checksum:i96A019F9DBA3528F
GO

Sequence cautioni

The sequence AAB86313.1 differs from that shown. Reason: Erroneous initiation. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000666 Genomic DNA. Translation: AAB86313.1. Different initiation.
PIRiA69114.
RefSeqiNP_276953.1. NC_000916.1.

Genome annotation databases

EnsemblBacteriaiAAB86313; AAB86313; MTH_1847.
GeneIDi1470932.
KEGGimth:MTH1847.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000666 Genomic DNA. Translation: AAB86313.1 . Different initiation.
PIRi A69114.
RefSeqi NP_276953.1. NC_000916.1.

3D structure databases

ProteinModelPortali O27875.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 187420.MTH1847.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAB86313 ; AAB86313 ; MTH_1847 .
GeneIDi 1470932.
KEGGi mth:MTH1847.

Phylogenomic databases

eggNOGi COG0717.
KOi K01494.
OMAi RPGMMIG.

Enzyme and pathway databases

UniPathwayi UPA00610 ; UER00665 .
BioCyci MTHE187420:GJNM-1851-MONOMER.

Family and domain databases

Gene3Di 2.70.40.10. 1 hit.
HAMAPi MF_00146. dCTP_deaminase.
InterProi IPR011962. dCTP_deam.
IPR029054. dUTPase-like.
IPR008180. dUTPase/dCTP_deaminase.
[Graphical view ]
Pfami PF00692. dUTPase. 1 hit.
[Graphical view ]
SUPFAMi SSF51283. SSF51283. 1 hit.
TIGRFAMsi TIGR02274. dCTP_deam. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H.

Entry informationi

Entry nameiDCD_METTH
AccessioniPrimary (citable) accession number: O27875
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: December 1, 2000
Last modified: October 1, 2014
This is version 87 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3