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Protein

Pyruvate synthase subunit PorC

Gene

porC

Organism
Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H) (Methanobacterium thermoautotrophicum)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

Catalytic activityi

Pyruvate + CoA + 2 oxidized ferredoxin = acetyl-CoA + CO2 + 2 reduced ferredoxin + 2 H+.

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Enzyme and pathway databases

BioCyciMetaCyc:MONOMER-14531.

Names & Taxonomyi

Protein namesi
Recommended name:
Pyruvate synthase subunit PorC (EC:1.2.7.1)
Alternative name(s):
Pyruvate oxidoreductase gamma chain
Short name:
POR
Pyruvic-ferredoxin oxidoreductase subunit gamma
Gene namesi
Name:porC
Ordered Locus Names:MTH_1740
OrganismiMethanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H) (Methanobacterium thermoautotrophicum)
Taxonomic identifieri187420 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanobacteriaMethanobacterialesMethanobacteriaceaeMethanothermobacter
Proteomesi
  • UP000005223 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 180180Pyruvate synthase subunit PorCPRO_0000099911Add
BLAST

Interactioni

Subunit structurei

Heterotetramer of one alpha, one beta, one delta and one gamma chain.

Protein-protein interaction databases

STRINGi187420.MTH1740.

Structurei

3D structure databases

ProteinModelPortaliO27772.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiarCOG01603. Archaea.
ENOG4102TVB. Archaea.
COG1014. LUCA.
COG1144. LUCA.
OMAiTTLMGAF.

Family and domain databases

Gene3Di3.40.920.10. 1 hit.
InterProiIPR011894. PorC_KorC.
IPR019752. Pyrv/ketoisovalerate_OxRed_cat.
IPR002869. Pyrv_flavodox_OxRed_cen.
[Graphical view]
PfamiPF01558. POR. 1 hit.
[Graphical view]
SUPFAMiSSF53323. SSF53323. 1 hit.
TIGRFAMsiTIGR02175. PorC_KorC. 1 hit.

Sequencei

Sequence statusi: Complete.

O27772-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIEIRFHGRG GQGAVTAAEI LAKAAFEDGK YSQAFPFFGV ERRGAPVMAF
60 70 80 90 100
TRIDDSPVRR RYQVYNPDYV VVLDEGLVDV VDVFSGLKDD GVVVLNKSGD
110 120 130 140 150
FQGGDVKVHT IDATGIALET LGRPIVNTVM LGAFAGVTGL VSIDSLIKII
160 170 180
KETFPGKIGE KNAEAARMAY EEIEKLRVNM
Length:180
Mass (Da):19,524
Last modified:May 30, 2000 - v2
Checksum:iF209CCFF749B2032
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000666 Genomic DNA. Translation: AAB86210.1. Different termination.

Genome annotation databases

EnsemblBacteriaiAAB86210; AAB86210; MTH_1740.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000666 Genomic DNA. Translation: AAB86210.1. Different termination.

3D structure databases

ProteinModelPortaliO27772.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi187420.MTH1740.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAB86210; AAB86210; MTH_1740.

Phylogenomic databases

eggNOGiarCOG01603. Archaea.
ENOG4102TVB. Archaea.
COG1014. LUCA.
COG1144. LUCA.
OMAiTTLMGAF.

Enzyme and pathway databases

BioCyciMetaCyc:MONOMER-14531.

Family and domain databases

Gene3Di3.40.920.10. 1 hit.
InterProiIPR011894. PorC_KorC.
IPR019752. Pyrv/ketoisovalerate_OxRed_cat.
IPR002869. Pyrv_flavodox_OxRed_cen.
[Graphical view]
PfamiPF01558. POR. 1 hit.
[Graphical view]
SUPFAMiSSF53323. SSF53323. 1 hit.
TIGRFAMsiTIGR02175. PorC_KorC. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H.

Entry informationi

Entry nameiPORC_METTH
AccessioniPrimary (citable) accession number: O27772
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: May 30, 2000
Last modified: November 11, 2015
This is version 77 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Caution

There seems to be a sequencing error that fuses together porC and porD. We have cut the ORF into its two constituents.Curated

Keywords - Technical termi

Complete proteome, Reference proteome

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.