O27771 (PORB_METTH) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Pyruvate synthase subunit porB
EC=1.2.7.1

Alternative name(s):
Pyruvate oxidoreductase beta chain
Short name=POR
Pyruvic-ferredoxin oxidoreductase subunit beta

Gene names

Name:	porB
Ordered Locus Names:	MTH_1738

Organism

Methanobacterium thermoautotrophicum (strain Delta H)

Taxonomic identifier

187420 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Methanobacteria › Methanobacteriales › Methanobacteriaceae › Methanothermobacter

Protein attributes

Sequence length	288 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Catalytic activity	Pyruvate + CoA + 2 oxidized ferredoxin = acetyl-CoA + CO2 + 2 reduced ferredoxin + 2 H+.
Subunit structure	Heterotetramer of one alpha, one beta, one delta and one gamma chain.

Ontologies

Keywords
Molecular function	Oxidoreductase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular function	pyruvate synthase activity Inferred from electronic annotation. Source: EC thiamine pyrophosphate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 288	288	Pyruvate synthase subunit porB		PRO_0000099904

Sequences

	Sequence		Length	Mass (Da)
	O27771 [UniParc]. Last modified January 1, 1998. Version 1. Checksum: BB77DD458A6B2A21	FASTA	288	31,594
	10 20 30 40 50 60 MKIPEEEFLA PGHRGCAGCG ATVGVRLALK VLGKNTVAVS STGCLEVITT PYPETAWRIP 70 80 90 100 110 120 WIHVAFENAA AVASGVERAL KAKGRDDVNV VAFAGDGGTA DIGLQALSGA MERGHNIIYI 130 140 150 160 170 180 CYDNEAYMNT GIQRSASTPY GASTTTSPHG KESFGEDRPK KNMPLIMAAH GVPYVATASI 190 200 210 220 230 240 SYPEDFMEKV RKAKETDGPA YIHLHQPCTT GWGFDPAKTV ELGRLAVETG SWILYEIEDG 250 260 270 280 DFRVTYRPVQ RKPVEEYLNA QKRFRHLTEE QKARIQEYVD SVCQELRI

References

[1]

"Complete genome sequence of Methanobacterium thermoautotrophicum deltaH: functional analysis and comparative genomics." Smith D.R., Doucette-Stamm L.A., Deloughery C., Lee H.-M., Dubois J., Aldredge T., Bashirzadeh R., Blakely D., Cook R., Gilbert K., Harrison D., Hoang L., Keagle P., Lumm W., Pothier B., Qiu D., Spadafora R., Vicare R. , Wang Y., Wierzbowski J., Gibson R., Jiwani N., Caruso A., Bush D., Safer H., Patwell D., Prabhakar S., McDougall S., Shimer G., Goyal A., Pietrovski S., Church G.M., Daniels C.J., Mao J.-I., Rice P., Noelling J., Reeve J.N. J. Bacteriol. 179:7135-7155(1997) [PubMed: 9371463] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Delta H.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE000666 Genomic DNA. Translation: AAB86208.1.
PIR	D69099.
RefSeq	NP_276848.1. NC_000916.1.
3D structure databases
ProteinModelPortal	O27771.
ModBase	Search...
Protein-protein interaction databases
STRING	O27771.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1470823.
GenomeReviews	Gene locus MTH_1738 in contig AE000666_GR.
KEGG	mth:MTH1738.
NMPDR	fig|187420.1.peg.1703.
Phylogenomic databases
eggNOG	arNOG04345.
HOGENOM	HBG313203.
OMA	PCILEIG.
ProtClustDB	PRK11865.
Enzyme and pathway databases
BioCyc	MetaCyc:MONOMER-14530. MTHE187420:MTH1738-MONOMER.
Family and domain databases
InterPro	IPR011766. TPP_enzyme-bd_C. [Graphical view]
KO	K00170.
Pfam	PF02775. TPP_enzyme_C. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PORB_METTH

Accession

Primary (citable) accession number: O27771

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2000
Last sequence update:	January 1, 1998
Last modified:	November 16, 2011
This is version 64 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program