Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

O27635

- ARCH_METTH

UniProt

O27635 - ARCH_METTH

Protein

Protein archease

Gene

MTH_1598

Organism
Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H) (Methanobacterium thermoautotrophicum)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 88 (01 Oct 2014)
      Sequence version 1 (01 Jan 1998)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently By similarity. May also act as a chaperone or modulator of proteins involved in DNA or RNA processing.By similarity

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi12 – 121CalciumBy similarity
    Metal bindingi139 – 1391CalciumBy similarity
    Metal bindingi140 – 1401Calcium; via carbonyl oxygenBy similarity

    Keywords - Biological processi

    tRNA processing

    Keywords - Ligandi

    Calcium, Metal-binding

    Enzyme and pathway databases

    BioCyciMTHE187420:GJNM-1600-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Protein archeaseUniRule annotation
    Gene namesi
    Ordered Locus Names:MTH_1598
    OrganismiMethanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H) (Methanobacterium thermoautotrophicum)
    Taxonomic identifieri187420 [NCBI]
    Taxonomic lineageiArchaeaEuryarchaeotaMethanobacteriaMethanobacterialesMethanobacteriaceaeMethanothermobacter
    ProteomesiUP000005223: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 140140Protein archeasePRO_0000068846Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi187420.MTH1598.

    Structurei

    Secondary structure

    1
    140
    Legend: HelixTurnBeta strand
    Show more details
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Beta strandi4 – 63
    Beta strandi10 – 189
    Beta strandi20 – 223
    Helixi23 – 3715
    Beta strandi48 – 5811
    Helixi59 – 7517
    Beta strandi84 – 896
    Beta strandi91 – 10111
    Beta strandi124 – 1285
    Beta strandi131 – 1399

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    1JW3NMR-A1-140[»]
    ProteinModelPortaliO27635.
    SMRiO27635. Positions 1-140.
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiO27635.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the archease family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG1371.
    OMAiPINKKYE.

    Family and domain databases

    Gene3Di3.55.10.10. 1 hit.
    HAMAPiMF_01222. Archease_arch.
    InterProiIPR002804. Archease.
    IPR022952. Archease_arc.
    IPR023572. Archease_dom.
    [Graphical view]
    PANTHERiPTHR12682. PTHR12682. 1 hit.
    PfamiPF01951. Archease. 1 hit.
    [Graphical view]
    ProDomiPD012969. PD012969. 1 hit.
    [Graphical view] [Entries sharing at least one domain]
    SUPFAMiSSF69819. SSF69819. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    O27635-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKGFEFFDVT ADAGFWAYGH DLEEVFENAA LAMFEVMTDT SLVEAAEERR    50
    VEITSEDRVS LLYDWLDELL FIHDTEFILF SKFKVKIDEK DDGLHLTGTA 100
    MGEEIKEGHE RRDEVKAVTF HMMEILDEDG LIKARVILDL 140
    Length:140
    Mass (Da):16,183
    Last modified:January 1, 1998 - v1
    Checksum:i1F82F57056E55AFC
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE000666 Genomic DNA. Translation: AAB86071.1.
    PIRiC69080.
    RefSeqiNP_276710.1. NC_000916.1.
    WP_010877206.1. NC_000916.1.

    Genome annotation databases

    EnsemblBacteriaiAAB86071; AAB86071; MTH_1598.
    GeneIDi1471867.
    KEGGimth:MTH1598.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE000666 Genomic DNA. Translation: AAB86071.1 .
    PIRi C69080.
    RefSeqi NP_276710.1. NC_000916.1.
    WP_010877206.1. NC_000916.1.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    1JW3 NMR - A 1-140 [» ]
    ProteinModelPortali O27635.
    SMRi O27635. Positions 1-140.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 187420.MTH1598.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAB86071 ; AAB86071 ; MTH_1598 .
    GeneIDi 1471867.
    KEGGi mth:MTH1598.

    Phylogenomic databases

    eggNOGi COG1371.
    OMAi PINKKYE.

    Enzyme and pathway databases

    BioCyci MTHE187420:GJNM-1600-MONOMER.

    Miscellaneous databases

    EvolutionaryTracei O27635.

    Family and domain databases

    Gene3Di 3.55.10.10. 1 hit.
    HAMAPi MF_01222. Archease_arch.
    InterProi IPR002804. Archease.
    IPR022952. Archease_arc.
    IPR023572. Archease_dom.
    [Graphical view ]
    PANTHERi PTHR12682. PTHR12682. 1 hit.
    Pfami PF01951. Archease. 1 hit.
    [Graphical view ]
    ProDomi PD012969. PD012969. 1 hit.
    [Graphical view ] [Entries sharing at least one domain ]
    SUPFAMi SSF69819. SSF69819. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H.
    2. "Predicted role for the archease protein family based on structural and sequence analysis of TM1083 and MTH1598, two proteins structurally characterized through structural genomics efforts."
      Canaves J.M.
      Proteins 56:19-27(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: PRELIMINARY FUNCTION.
    3. Cited for: STRUCTURE BY NMR.

    Entry informationi

    Entry nameiARCH_METTH
    AccessioniPrimary (citable) accession number: O27635
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: September 19, 2002
    Last sequence update: January 1, 1998
    Last modified: October 1, 2014
    This is version 88 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    3D-structure, Complete proteome, Reference proteome

    Documents

    1. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3