O27635 (ARCH_METTH) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Protein archease

Gene names

Ordered Locus Names:

MTH_1598

Organism

Methanobacterium thermoautotrophicum (strain Delta H)

Taxonomic identifier

187420 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Methanobacteria › Methanobacteriales › Methanobacteriaceae › Methanothermobacter

Protein attributes

Sequence length	140 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Chaperone or modulator of proteins involved in DNA or RNA processing Probable. Ref.2
Sequence similarities	Belongs to the archease family.

Ontologies

Keywords
Molecular function	Chaperone
Technical term	3D-structure Complete proteome Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

1 – 140

140

Protein archease HAMAP MF_01222

PRO_0000068846

Secondary structure

1

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140

Helix Strand Turn

Details...

Beta strand

4 – 6

3

Beta strand

10 – 18

9

Beta strand

20 – 22

3

Helix

23 – 37

15

Beta strand

48 – 58

11

Helix

59 – 75

17

Beta strand

84 – 89

6

Beta strand

91 – 101

11

Beta strand

124 – 128

5

Beta strand

131 – 139

9

Sequences

	Sequence		Length	Mass (Da)
	O27635 [UniParc]. Last modified January 1, 1998. Version 1. Checksum: 1F82F57056E55AFC	FASTA	140	16,183
	10 20 30 40 50 60 MKGFEFFDVT ADAGFWAYGH DLEEVFENAA LAMFEVMTDT SLVEAAEERR VEITSEDRVS 70 80 90 100 110 120 LLYDWLDELL FIHDTEFILF SKFKVKIDEK DDGLHLTGTA MGEEIKEGHE RRDEVKAVTF 130 140 HMMEILDEDG LIKARVILDL

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Complete genome sequence of Methanobacterium thermoautotrophicum deltaH: functional analysis and comparative genomics." Smith D.R., Doucette-Stamm L.A., Deloughery C., Lee H.-M., Dubois J., Aldredge T., Bashirzadeh R., Blakely D., Cook R., Gilbert K., Harrison D., Hoang L., Keagle P., Lumm W., Pothier B., Qiu D., Spadafora R., Vicare R. , Wang Y., Wierzbowski J., Gibson R., Jiwani N., Caruso A., Bush D., Safer H., Patwell D., Prabhakar S., McDougall S., Shimer G., Goyal A., Pietrovski S., Church G.M., Daniels C.J., Mao J.-I., Rice P., Noelling J., Reeve J.N. J. Bacteriol. 179:7135-7155(1997) [PubMed: 9371463] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Delta H.
[2]	"Predicted role for the archease protein family based on structural and sequence analysis of TM1083 and MTH1598, two proteins structurally characterized through structural genomics efforts." Canaves J.M. Proteins 56:19-27(2004) [PubMed: 15162483] [Abstract] Cited for: PRELIMINARY FUNCTION.
[3]	"An NMR approach to structural proteomics." Yee A., Chang X., Pineda-Lucena A., Wu B., Semesi A., Le B., Ramelot T., Lee G.M., Bhattacharyya S., Gutierrez P., Denisov A., Lee C.-H., Cort J.R., Kozlov G., Liao J., Finak G., Chen L., Wishart D. , Lee W., McIntosh L.P., Gehring K., Kennedy M.A., Edwards A.M., Arrowsmith C.H. Proc. Natl. Acad. Sci. U.S.A. 99:1825-1830(2002) [PubMed: 11854485] [Abstract] Cited for: STRUCTURE BY NMR.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AE000666 Genomic DNA. Translation: AAB86071.1.

PIR

C69080.

RefSeq

NP_276710.1. NC_000916.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
1JW3	NMR	-	A	1-140	[»]

ProteinModelPortal

O27635.

SMR

O27635. Positions 1-140.

ModBase

Search...

Protein-protein interaction databases

STRING

O27635.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

GeneID

1471867.

GenomeReviews

Gene locus MTH_1598 in contig AE000666_GR.

KEGG

mth:MTH1598.

NMPDR

fig|187420.1.peg.1565.

Phylogenomic databases

eggNOG

arNOG12913.

HOGENOM

HBG729173.

OMA

EAFEQCG.

ProtClustDB

CLSK798219.

Enzyme and pathway databases

BioCyc

MTHE187420:MTH1598-MONOMER.

Family and domain databases

HAMAP

MF_01222. Archease_arch.
[Tree]

InterPro

IPR002804. Archease.
IPR022952. Archease_arc.
IPR023572. Archease_dom.
[Graphical view]

Gene3D

G3DSA:3.55.10.10. DUF101. 1 hit.

PANTHER

PTHR12682. DUF101. 1 hit.

Pfam

PF01951. Archease. 1 hit.
[Graphical view]

ProDom

PD012969. PD012969. 1 hit.
[Graphical view] [Entries sharing at least one domain]

SUPFAM

SSF69819. DUF101. 1 hit.

ProtoNet

Search...

Entry information

Entry name

ARCH_METTH

Accession

Primary (citable) accession number: O27635

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 19, 2002
Last sequence update:	January 1, 1998
Last modified:	December 14, 2011
This is version 74 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program