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O27479

- UPPP_METTH

UniProt

O27479 - UPPP_METTH

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Protein

Undecaprenyl-diphosphatase

Gene
uppP, bacA, upk, MTH_1428
Organism
Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H) (Methanobacterium thermoautotrophicum)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP) By similarity.

Catalytic activityi

Ditrans,octacis-undecaprenyl diphosphate + H2O = ditrans,octacis-undecaprenyl phosphate + phosphate.

GO - Molecular functioni

  1. undecaprenyl-diphosphatase activity Source: UniProtKB-EC

GO - Biological processi

  1. dephosphorylation Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Enzyme and pathway databases

BioCyciMTHE187420:GJNM-1430-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Undecaprenyl-diphosphatase (EC:3.6.1.27)
Alternative name(s):
Undecaprenyl pyrophosphate phosphatase
Gene namesi
Name:uppP
Synonyms:bacA, upk
Ordered Locus Names:MTH_1428
OrganismiMethanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H) (Methanobacterium thermoautotrophicum)
Taxonomic identifieri187420 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanobacteriaMethanobacterialesMethanobacteriaceaeMethanothermobacter
ProteomesiUP000005223: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei23 – 4321Helical; Reviewed predictionAdd
BLAST
Transmembranei105 – 12521Helical; Reviewed predictionAdd
BLAST
Transmembranei129 – 14921Helical; Reviewed predictionAdd
BLAST
Transmembranei161 – 18121Helical; Reviewed predictionAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 181181Undecaprenyl-diphosphatasePRO_0000151252Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi187420.MTH1428.

Family & Domainsi

Sequence similaritiesi

Belongs to the UppP family.

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG1968.
KOiK06153.
OMAiMEQINIG.

Family and domain databases

InterProiIPR003824. UppP.
[Graphical view]
PfamiPF02673. BacA. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O27479-1 [UniParc]FASTAAdd to Basket

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MVIIGTVPAG LAGVLFKDFF ESLFSSLTAV GFFLLVTGFL LWGSENISRR    50
VREKLPVEKL GVRESLIIGC AQALAIAPGI SRSGATISAG LFLGFERELA 100
ARYSFLLSIP AILGAALIQI KDIGAGMNLL GASMVAGFAA AAVSGYIAIK 150
FLLKLIKERD LYIFAYYCWA LGIMILAAAL I 181
Length:181
Mass (Da):19,211
Last modified:January 1, 1998 - v1
Checksum:i82D1F852B3E90851
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE000666 Genomic DNA. Translation: AAB85905.1.
PIRiC69057.
RefSeqiNP_276544.1. NC_000916.1.

Genome annotation databases

EnsemblBacteriaiAAB85905; AAB85905; MTH_1428.
GeneIDi1471145.
KEGGimth:MTH1428.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE000666 Genomic DNA. Translation: AAB85905.1 .
PIRi C69057.
RefSeqi NP_276544.1. NC_000916.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 187420.MTH1428.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAB85905 ; AAB85905 ; MTH_1428 .
GeneIDi 1471145.
KEGGi mth:MTH1428.

Phylogenomic databases

eggNOGi COG1968.
KOi K06153.
OMAi MEQINIG.

Enzyme and pathway databases

BioCyci MTHE187420:GJNM-1430-MONOMER.

Family and domain databases

InterProi IPR003824. UppP.
[Graphical view ]
Pfami PF02673. BacA. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H.

Entry informationi

Entry nameiUPPP_METTH
AccessioniPrimary (citable) accession number: O27479
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 13, 2004
Last sequence update: January 1, 1998
Last modified: May 14, 2014
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3