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O27479

- UPPP_METTH

UniProt

O27479 - UPPP_METTH

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Protein

Undecaprenyl-diphosphatase

Gene

uppP

Organism
Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H) (Methanobacterium thermoautotrophicum)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).By similarity

Catalytic activityi

Ditrans,octacis-undecaprenyl diphosphate + H2O = ditrans,octacis-undecaprenyl phosphate + phosphate.

GO - Molecular functioni

  1. undecaprenyl-diphosphatase activity Source: UniProtKB-EC

GO - Biological processi

  1. dephosphorylation Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Enzyme and pathway databases

BioCyciMTHE187420:GJNM-1430-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Undecaprenyl-diphosphatase (EC:3.6.1.27)
Alternative name(s):
Undecaprenyl pyrophosphate phosphatase
Gene namesi
Name:uppP
Synonyms:bacA, upk
Ordered Locus Names:MTH_1428
OrganismiMethanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H) (Methanobacterium thermoautotrophicum)
Taxonomic identifieri187420 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanobacteriaMethanobacterialesMethanobacteriaceaeMethanothermobacter
ProteomesiUP000005223: Chromosome

Subcellular locationi

Cell membrane By similarity; Multi-pass membrane protein By similarity

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 181181Undecaprenyl-diphosphatasePRO_0000151252Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi187420.MTH1428.

Structurei

Transmembrane

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei23 – 4321HelicalSequence AnalysisAdd
BLAST
Transmembranei105 – 12521HelicalSequence AnalysisAdd
BLAST
Transmembranei129 – 14921HelicalSequence AnalysisAdd
BLAST
Transmembranei161 – 18121HelicalSequence AnalysisAdd
BLAST

Family & Domainsi

Sequence similaritiesi

Belongs to the UppP family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG1968.
KOiK06153.
OMAiMEQINIG.

Family and domain databases

InterProiIPR003824. UppP.
[Graphical view]
PfamiPF02673. BacA. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O27479-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MVIIGTVPAG LAGVLFKDFF ESLFSSLTAV GFFLLVTGFL LWGSENISRR
60 70 80 90 100
VREKLPVEKL GVRESLIIGC AQALAIAPGI SRSGATISAG LFLGFERELA
110 120 130 140 150
ARYSFLLSIP AILGAALIQI KDIGAGMNLL GASMVAGFAA AAVSGYIAIK
160 170 180
FLLKLIKERD LYIFAYYCWA LGIMILAAAL I
Length:181
Mass (Da):19,211
Last modified:January 1, 1998 - v1
Checksum:i82D1F852B3E90851
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE000666 Genomic DNA. Translation: AAB85905.1.
PIRiC69057.
RefSeqiNP_276544.1. NC_000916.1.

Genome annotation databases

EnsemblBacteriaiAAB85905; AAB85905; MTH_1428.
GeneIDi1471145.
KEGGimth:MTH1428.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE000666 Genomic DNA. Translation: AAB85905.1 .
PIRi C69057.
RefSeqi NP_276544.1. NC_000916.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 187420.MTH1428.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAB85905 ; AAB85905 ; MTH_1428 .
GeneIDi 1471145.
KEGGi mth:MTH1428.

Phylogenomic databases

eggNOGi COG1968.
KOi K06153.
OMAi MEQINIG.

Enzyme and pathway databases

BioCyci MTHE187420:GJNM-1430-MONOMER.

Family and domain databases

InterProi IPR003824. UppP.
[Graphical view ]
Pfami PF02673. BacA. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H.

Entry informationi

Entry nameiUPPP_METTH
AccessioniPrimary (citable) accession number: O27479
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 13, 2004
Last sequence update: January 1, 1998
Last modified: October 29, 2014
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3