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Protein
Submitted name:

Conserved protein

Gene

MTH_1368

Organism
Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H) (Methanobacterium thermoautotrophicum)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Enzyme and pathway databases

BioCyciMTHE187420:GJNM-1370-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Conserved proteinImported
Gene namesi
Ordered Locus Names:MTH_1368Imported
OrganismiMethanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H) (Methanobacterium thermoautotrophicum)Imported
Taxonomic identifieri187420 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanobacteriaMethanobacterialesMethanobacteriaceaeMethanothermobacter
Proteomesi
  • UP000005223 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei6 – 2520HelicalSequence analysisAdd
BLAST
Transmembranei62 – 8322HelicalSequence analysisAdd
BLAST
Transmembranei113 – 13422HelicalSequence analysisAdd
BLAST
Transmembranei176 – 19823HelicalSequence analysisAdd
BLAST
Transmembranei317 – 33620HelicalSequence analysisAdd
BLAST
Transmembranei357 – 37923HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Interactioni

Protein-protein interaction databases

STRINGi187420.MTH1368.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2HGANMR-A208-310[»]
ProteinModelPortaliO27421.
SMRiO27421. Positions 208-310.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiO27421.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini196 – 26873PDZ (DHR)InterPro annotationAdd
BLAST

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiarCOG04064. Archaea.
COG0750. LUCA.
OMAiTIPLWYG.

Family and domain databases

Gene3Di2.30.42.10. 1 hit.
InterProiIPR001193. MBTPS2.
IPR001478. PDZ.
IPR008915. Peptidase_M50.
[Graphical view]
PANTHERiPTHR13325. PTHR13325. 1 hit.
PfamiPF02163. Peptidase_M50. 1 hit.
[Graphical view]
PRINTSiPR01000. SREBPS2PTASE.
SMARTiSM00228. PDZ. 1 hit.
[Graphical view]
SUPFAMiSSF50156. SSF50156. 1 hit.
PROSITEiPS50106. PDZ. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O27421-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLSDMNALWF YLIAFILIWT MAILFRDRLK IEIHGPLLMR RTKRLRGFID
60 70 80 90 100
GLASGHPKLW RWIMNAGIPV AFFFMFYMLY MLVMSLQNIF VTPQASLIVP
110 120 130 140 150
GVDIPGSPVY VPLGYGIIGL ATVIVVHEFA HGILARLEGV RIKSIGLLLL
160 170 180 190 200
AILPGAFVEP DEEDIKKIRP ISKMRIYAAG SVANLILAGI CFALFFGISS
210 220 230 240 250
FAMPAAFQPD GVQIDSVVPG SPASKVLTPG LVIESINGMP TSNLTTYSAA
260 270 280 290 300
LKTISVGEVI NITTDQGTFH LKTGRNPNNS SRAYMGIRTS NHLRVRDSVA
310 320 330 340 350
SVLGDTLPFA LTYLEELFFW IFFLNFAVGT VNLLPAKPLD GGLMFEELLR
360 370 380
YRLPERIVKP AVSYVSIFVI LIIAVSIIWG TGRGLLMIF
Length:389
Mass (Da):42,956
Last modified:January 1, 1998 - v1
Checksum:iDA5F463DC6530484
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000666 Genomic DNA. Translation: AAB85845.1.
PIRiH69048.

Genome annotation databases

EnsemblBacteriaiAAB85845; AAB85845; MTH_1368.
KEGGimth:MTH_1368.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000666 Genomic DNA. Translation: AAB85845.1.
PIRiH69048.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2HGANMR-A208-310[»]
ProteinModelPortaliO27421.
SMRiO27421. Positions 208-310.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi187420.MTH1368.

Protocols and materials databases

DNASUi1471085.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAB85845; AAB85845; MTH_1368.
KEGGimth:MTH_1368.

Phylogenomic databases

eggNOGiarCOG04064. Archaea.
COG0750. LUCA.
OMAiTIPLWYG.

Enzyme and pathway databases

BioCyciMTHE187420:GJNM-1370-MONOMER.

Miscellaneous databases

EvolutionaryTraceiO27421.

Family and domain databases

Gene3Di2.30.42.10. 1 hit.
InterProiIPR001193. MBTPS2.
IPR001478. PDZ.
IPR008915. Peptidase_M50.
[Graphical view]
PANTHERiPTHR13325. PTHR13325. 1 hit.
PfamiPF02163. Peptidase_M50. 1 hit.
[Graphical view]
PRINTSiPR01000. SREBPS2PTASE.
SMARTiSM00228. PDZ. 1 hit.
[Graphical view]
SUPFAMiSSF50156. SSF50156. 1 hit.
PROSITEiPS50106. PDZ. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiO27421_METTH
AccessioniPrimary (citable) accession number: O27421
Entry historyi
Integrated into UniProtKB/TrEMBL: January 1, 1998
Last sequence update: January 1, 1998
Last modified: July 6, 2016
This is version 92 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.