O27372 (RPOL_METTH) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
DNA-directed RNA polymerase subunit L
EC=2.7.7.6

Gene names

Name:	rpoL
Ordered Locus Names:	MTH_1317

Organism

Methanobacterium thermoautotrophicum (strain Delta H)

Taxonomic identifier

187420 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Methanobacteria › Methanobacteriales › Methanobacteriaceae › Methanothermobacter

Protein attributes

Sequence length	85 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. HAMAP MF_00261
Catalytic activity	Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). HAMAP MF_00261
Sequence similarities	Belongs to the archaeal rpoL/eukaryotic RPB11/RPC19 RNA polymerase subunit family.

Ontologies

Keywords
Biological process	Transcription
Cellular component	DNA-directed RNA polymerase
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular function	DNA binding Inferred from electronic annotation. Source: InterPro DNA-directed RNA polymerase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 85	85	DNA-directed RNA polymerase subunit L HAMAP MF_00261		PRO_0000149330

Sequences

	Sequence		Length	Mass (Da)
	O27372 [UniParc]. Last modified January 1, 1998. Version 1. Checksum: CDB234326B4C765A	FASTA	85	9,732
	10 20 30 40 50 60 MEVILDKRNE MEIVFEGETH TLCNVLRSIL MEDEKVKAAA YSIDHPIVGE PQLYIRAGSP 70 80 KKSLKAAAET LRDRCDEFRR LIESL

References

[1]

"Complete genome sequence of Methanobacterium thermoautotrophicum deltaH: functional analysis and comparative genomics." Smith D.R., Doucette-Stamm L.A., Deloughery C., Lee H.-M., Dubois J., Aldredge T., Bashirzadeh R., Blakely D., Cook R., Gilbert K., Harrison D., Hoang L., Keagle P., Lumm W., Pothier B., Qiu D., Spadafora R., Vicare R. , Wang Y., Wierzbowski J., Gibson R., Jiwani N., Caruso A., Bush D., Safer H., Patwell D., Prabhakar S., McDougall S., Shimer G., Goyal A., Pietrovski S., Church G.M., Daniels C.J., Mao J.-I., Rice P., Noelling J., Reeve J.N. J. Bacteriol. 179:7135-7155(1997) [PubMed: 9371463] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Delta H.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE000666 Genomic DNA. Translation: AAB85795.1.
PIR	A69042.
RefSeq	NP_276434.1. NC_000916.1.
3D structure databases
ProteinModelPortal	O27372.
ModBase	Search...
Protein-protein interaction databases
STRING	O27372.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1471034.
GenomeReviews	Gene locus MTH_1317 in contig AE000666_GR.
KEGG	mth:MTH1317.
NMPDR	fig|187420.1.peg.1289.
Phylogenomic databases
eggNOG	arNOG11156.
HOGENOM	HBG726964.
OMA	RSILMED.
PhylomeDB	O27372.
ProtClustDB	PRK01146.
Enzyme and pathway databases
BioCyc	MTHE187420:MTH1317-MONOMER.
Family and domain databases
HAMAP	MF_00261. RNApol_arch_L. [Tree]
InterPro	IPR009025. DNA-dir_RNA_pol_RBP11-like. IPR022905. DNA-dir_RNApol_L_arc. IPR008193. RNA_pol_Rpb11_13-16kDa_CS. [Graphical view]
KO	K03056.
SUPFAM	SSF55257. RNAP_RBP11-like. 1 hit.
PROSITE	PS01154. RNA_POL_L_13KD. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RPOL_METTH

Accession

Primary (citable) accession number: O27372

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 1, 2000
Last sequence update:	January 1, 1998
Last modified:	November 16, 2011
This is version 76 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program