Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Chaperone protein DnaK

Gene

dnaK

Organism
Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H) (Methanobacterium thermoautotrophicum)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Acts as a chaperone.By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Chaperone

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Chaperone protein DnaK
Alternative name(s):
HSP70
Heat shock 70 kDa protein
Heat shock protein 70
Gene namesi
Name:dnaK
Ordered Locus Names:MTH_1290
OrganismiMethanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H) (Methanobacterium thermoautotrophicum)
Taxonomic identifieri187420 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanobacteriaMethanobacterialesMethanobacteriaceaeMethanothermobacter
Proteomesi
  • UP000005223 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000785991 – 596Chaperone protein DnaKAdd BLAST596

Proteomic databases

PRIDEiO27351.

Interactioni

Protein-protein interaction databases

STRINGi187420.MTH1290.

Structurei

3D structure databases

ProteinModelPortaliO27351.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the heat shock protein 70 family.Curated

Phylogenomic databases

eggNOGiarCOG03060. Archaea.
COG0443. LUCA.
KOiK04043.
OMAiFYSAKRF.

Family and domain databases

Gene3Di1.20.1270.10. 1 hit.
2.60.34.10. 1 hit.
HAMAPiMF_00332. DnaK. 1 hit.
InterProiIPR012725. Chaperone_DnaK.
IPR018181. Heat_shock_70_CS.
IPR029048. HSP70_C.
IPR029047. HSP70_peptide-bd.
IPR013126. Hsp_70_fam.
[Graphical view]
PfamiPF00012. HSP70. 1 hit.
[Graphical view]
PRINTSiPR00301. HEATSHOCK70.
SUPFAMiSSF100920. SSF100920. 1 hit.
SSF100934. SSF100934. 1 hit.
TIGRFAMsiTIGR02350. prok_dnaK. 1 hit.
PROSITEiPS00297. HSP70_1. 1 hit.
PS00329. HSP70_2. 1 hit.
PS01036. HSP70_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O27351-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKKEKILGI DLGTSNSAAA VLIGGKPTII PSAEGASQYG KSFPSCVAFT
60 70 80 90 100
EDGQMLVGEP ARRQAVTNPE NTITAIKRSM GTDRKVKVHG KEYTPQEISA
110 120 130 140 150
FILQKIKKDA EAFLGEEIKK AVITVPAYFD DNQRTATKDA GTIAGLDVVR
160 170 180 190 200
LVNEPTAASL AYGLDKEDED MVIMVFDLGG GTLDVTIMEF GGGVFEVRST
210 220 230 240 250
SGDTQLGGTD MDNAIMNYLA EEFKMETGID LMEDDQAVQR LREAAEKAKI
260 270 280 290 300
ELSTTLTTEV NLPYITVAQD GPKHLIKTIT RAKLEELVDP IVQKCAGPME
310 320 330 340 350
QALRDAGMTR EDVDKIILVG GPTRMPIVQK FVEDFIGKPV ERGIDPMECV
360 370 380 390 400
AMGAAIQGGV LAGEIKDLVL LDVTPLSLGI ETLGGVFTKL IERNTTIPTR
410 420 430 440 450
KSQIFSTAAD NQTSVDIHVL QGERPMAADN TSLGRFQLVG IPPAPRGVPQ
460 470 480 490 500
IEVTFDIDAN GILNVSAKDL GTGKEQAITI TAPNKLSEEE IKQKIEEAKK
510 520 530 540 550
HAEEDRRKQE EIEIRNNADS MIYTAEKTLD ELGDKVPAEK KEEVEKQVRE
560 570 580 590
LRELIAGDDI QAIKSKTEEL TKTVQEIGVS YIPAGSTATS STAAGR
Length:596
Mass (Da):64,460
Last modified:January 1, 1998 - v1
Checksum:iE8B9C41D05A922B6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000666 Genomic DNA. Translation: AAB85772.1.
PIRiG69038.
RefSeqiWP_010876907.1. NC_000916.1.

Genome annotation databases

EnsemblBacteriaiAAB85772; AAB85772; MTH_1290.
GeneIDi1471698.
KEGGimth:MTH_1290.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000666 Genomic DNA. Translation: AAB85772.1.
PIRiG69038.
RefSeqiWP_010876907.1. NC_000916.1.

3D structure databases

ProteinModelPortaliO27351.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi187420.MTH1290.

Proteomic databases

PRIDEiO27351.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAB85772; AAB85772; MTH_1290.
GeneIDi1471698.
KEGGimth:MTH_1290.

Phylogenomic databases

eggNOGiarCOG03060. Archaea.
COG0443. LUCA.
KOiK04043.
OMAiFYSAKRF.

Family and domain databases

Gene3Di1.20.1270.10. 1 hit.
2.60.34.10. 1 hit.
HAMAPiMF_00332. DnaK. 1 hit.
InterProiIPR012725. Chaperone_DnaK.
IPR018181. Heat_shock_70_CS.
IPR029048. HSP70_C.
IPR029047. HSP70_peptide-bd.
IPR013126. Hsp_70_fam.
[Graphical view]
PfamiPF00012. HSP70. 1 hit.
[Graphical view]
PRINTSiPR00301. HEATSHOCK70.
SUPFAMiSSF100920. SSF100920. 1 hit.
SSF100934. SSF100934. 1 hit.
TIGRFAMsiTIGR02350. prok_dnaK. 1 hit.
PROSITEiPS00297. HSP70_1. 1 hit.
PS00329. HSP70_2. 1 hit.
PS01036. HSP70_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiDNAK_METTH
AccessioniPrimary (citable) accession number: O27351
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: January 1, 1998
Last modified: November 2, 2016
This is version 94 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.