O27255 (Y1187_METTH) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
UPF0045 protein MTH_1187

Gene names

Ordered Locus Names:

MTH_1187

Organism

Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H) (Methanobacterium thermoautotrophicum)

Taxonomic identifier

187420 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Methanobacteria › Methanobacteriales › Methanobacteriaceae › Methanothermobacter

Protein attributes

Sequence length	99 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Subunit structure	Homotetramer.
Sequence similarities	Belongs to the UPF0045 family.

Ontologies

Keywords
Technical term	3D-structure Complete proteome Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

1 – 99

99

UPF0045 protein MTH_1187

PRO_0000147629

Secondary structure

1

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

99

Helix Strand Turn

Details...

Beta strand

2 – 12

11

Beta strand

14 – 16

3

Helix

19 – 29

11

Beta strand

35 – 39

5

Beta strand

42 – 49

8

Helix

50 – 66

17

Beta strand

70 – 84

15

Helix

88 – 98

11

Sequences

	Sequence		Length	Mass (Da)
	O27255 [UniParc]. Last modified January 1, 1998. Version 1. Checksum: 32D48B66A74C7430	FASTA	99	10,798
	10 20 30 40 50 60 MITAELTVIP LGTCSTSLSS YVAAAVEALK KLNVRYEISG MGTLLEAEDL DELMEAVKAA 70 80 90 HEAVLQAGSD RVYTTLKIDD RRDADRGLRD KVESVKEKI

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Complete genome sequence of Methanobacterium thermoautotrophicum deltaH: functional analysis and comparative genomics." Smith D.R., Doucette-Stamm L.A., Deloughery C., Lee H.-M., Dubois J., Aldredge T., Bashirzadeh R., Blakely D., Cook R., Gilbert K., Harrison D., Hoang L., Keagle P., Lumm W., Pothier B., Qiu D., Spadafora R., Vicare R. , Wang Y., Wierzbowski J., Gibson R., Jiwani N., Caruso A., Bush D., Safer H., Patwell D., Prabhakar S., McDougall S., Shimer G., Goyal A., Pietrovski S., Church G.M., Daniels C.J., Mao J.-I., Rice P., Noelling J., Reeve J.N. J. Bacteriol. 179:7135-7155(1997) [PubMed: 9371463] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H.
[2]	"Crystal structures of MTH1187 and its yeast ortholog YBL001c." Tao X., Khayat R., Christendat D., Savchenko A., Xu X., Goldsmith-Fischman S., Honig B., Edwards A., Arrowsmith C.H., Tong L. Proteins 52:478-480(2003) [PubMed: 12866058] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (2.3 ANGSTROMS).

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AE000666 Genomic DNA. Translation: AAB85676.1.

PIR

C69025.

RefSeq

NP_276315.1. NC_000916.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
1LXN	X-ray	2.30	A/B/C/D	1-99	[»]

ProteinModelPortal

O27255.

SMR

O27255. Positions 1-99.

ModBase

Search...

Protein-protein interaction databases

STRING

O27255.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

GeneID

1471595.

GenomeReviews

Gene locus MTH_1187 in contig AE000666_GR.

KEGG

mth:MTH1187.

Phylogenomic databases

eggNOG

COG0011.

OMA

EAHELMF.

ProtClustDB

CLSK2750518.

Enzyme and pathway databases

BioCyc

MTHE187420:MTH1187-MONOMER.

Family and domain databases

Gene3D

G3DSA:3.30.70.930. DUF77. 1 hit.

InterPro

IPR002767. DUF77.
IPR016198. Thiamin/HMP-bd-like_put.
[Graphical view]

Pfam

PF01910. DUF77. 1 hit.
[Graphical view]

SUPFAM

SSF89957. Put_thiamin/HMP-bd-like. 1 hit.

TIGRFAMs

TIGR00106. TIGR00106. 1 hit.

ProtoNet

Search...

Other

EvolutionaryTrace

O27255.

Entry information

Entry name

Y1187_METTH

Accession

Primary (citable) accession number: O27255

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 15, 1998
Last sequence update:	January 1, 1998
Last modified:	May 16, 2012
This is version 74 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program