Reviewed, UniProtKB/Swiss-Prot O27114 (KORC_METTH)

Names and origin

Protein names

Recommended name:
    2-oxoglutarate synthase subunit korC
    EC=1.2.7.3
Alternative name(s):
    2-ketoglutarate oxidoreductase gamma chain
      Short name=KOR
    2-oxoglutarate-ferredoxin oxidoreductase subunit gamma

Gene names

Name:	korC
Ordered Locus Names:	MTH_1035

Organism

Methanobacterium thermoautotrophicum [Complete proteome] [HAMAP]

Taxonomic identifier

187420 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Methanobacteria › Methanobacteriales › Methanobacteriaceae › Methanothermobacter

Protein attributes

Sequence length	189 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Predicted.

General annotation (Comments)

Catalytic activity	2-oxoglutarate + CoA + 2 oxidized ferredoxin = succinyl-CoA + CO2 + 2 reduced ferredoxin + 2 H+.
Subunit structure	Heterotetramer of the korA, korB, korC and korD subunits.

Ontologies

Keywords
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	2-oxoglutarate synthase activity Inferred from electronic annotation. Source: EC electron carrier activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 189	189	2-oxoglutarate synthase subunit korC		PRO_0000099947

Sequences

	Sequence		Length	Mass (Da)
	O27114-1 [UniParc]. Last modified January 1, 1998. Version 1. Checksum: 335EF064D7318C3C	FASTA	189	20,380
	10 20 30 40 50 60 MIEVRKEIRI AGFGGQGVIL AGIVLGKAAS LYDGLYAVQT QSYGPEARGG ASRAEVVISD 70 80 90 100 110 120 HEIDYPKVQS PDILVAMSHQ ALLTYMDDLK RGGALIVDPD MVVEAEIEDF IRAREVKYFR 130 140 150 160 170 180 APATRTAEER VGITIVANMV MIGALTEATG IVSVRAAEEA IKDSVPPGTE EKNLMAFQAG RELIMEGSR

References

[1]

"Complete genome sequence of Methanobacterium thermoautotrophicum deltaH: functional analysis and comparative genomics." Smith D.R., Doucette-Stamm L.A., Deloughery C., Lee H.-M., Dubois J., Aldredge T., Bashirzadeh R., Blakely D., Cook R., Gilbert K., Harrison D., Hoang L., Keagle P., Lumm W., Pothier B., Qiu D., Spadafora R., Vicare R. , Wang Y., Wierzbowski J., Gibson R., Jiwani N., Caruso A., Bush D., Safer H., Patwell D., Prabhakar S., McDougall S., Shimer G., Goyal A., Pietrovski S., Church G.M., Daniels C.J., Mao J.-I., Rice P., Noelling J., Reeve J.N. J. Bacteriol. 179:7135-7155(1997) [PubMed: 9371463] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Delta H.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE000666 Genomic DNA. Translation: AAB85531.1.
PIR	B69005.
RefSeq	NP_276170.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	1471443.
GenomeReviews	Gene locus MTH_1035 in contig AE000666_GR.
KEGG	mth:MTH1035.
NMPDR	fig|187420.1.peg.1025.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	O27114.
OMA	O27114. PYANEGE.
Enzyme and pathway databases
BioCyc	MTHE187420:MTH1035-MON.
BRENDA	1.2.7.3. 270.
Family and domain databases
InterPro	IPR019752. Pyrv/ketoisovalerate_OxRed. [Graphical view]
Gene3D	G3DSA:3.40.920.10. Pyrv_Fd/Flavodoxin_OxRdtase. 1 hit.
Pfam	PF01558. POR. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

KORC_METTH

Accession

Primary (citable) accession number: O27114

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2000
Last sequence update:	January 1, 1998
Last modified:	June 16, 2009
This is version 50 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)