O27114 (KORC_METTH) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
2-oxoglutarate synthase subunit korC
EC=1.2.7.3

Alternative name(s):
2-ketoglutarate oxidoreductase gamma chain
Short name=KOR
2-oxoglutarate-ferredoxin oxidoreductase subunit gamma

Gene names

Name:	korC
Ordered Locus Names:	MTH_1035

Organism

Methanobacterium thermoautotrophicum (strain Delta H)

Taxonomic identifier

187420 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Methanobacteria › Methanobacteriales › Methanobacteriaceae › Methanothermobacter

Protein attributes

Sequence length	189 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Catalytic activity	2-oxoglutarate + CoA + 2 oxidized ferredoxin = succinyl-CoA + CO2 + 2 reduced ferredoxin + 2 H+.
Subunit structure	Heterotetramer of the korA, korB, korC and korD subunits.

Ontologies

Keywords
Molecular function	Oxidoreductase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular function	2-oxoglutarate synthase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 189	189	2-oxoglutarate synthase subunit korC		PRO_0000099947

Sequences

	Sequence		Length	Mass (Da)
	O27114 [UniParc]. Last modified January 1, 1998. Version 1. Checksum: 335EF064D7318C3C	FASTA	189	20,380
	10 20 30 40 50 60 MIEVRKEIRI AGFGGQGVIL AGIVLGKAAS LYDGLYAVQT QSYGPEARGG ASRAEVVISD 70 80 90 100 110 120 HEIDYPKVQS PDILVAMSHQ ALLTYMDDLK RGGALIVDPD MVVEAEIEDF IRAREVKYFR 130 140 150 160 170 180 APATRTAEER VGITIVANMV MIGALTEATG IVSVRAAEEA IKDSVPPGTE EKNLMAFQAG RELIMEGSR

References

[1]

"Complete genome sequence of Methanobacterium thermoautotrophicum deltaH: functional analysis and comparative genomics." Smith D.R., Doucette-Stamm L.A., Deloughery C., Lee H.-M., Dubois J., Aldredge T., Bashirzadeh R., Blakely D., Cook R., Gilbert K., Harrison D., Hoang L., Keagle P., Lumm W., Pothier B., Qiu D., Spadafora R., Vicare R. , Wang Y., Wierzbowski J., Gibson R., Jiwani N., Caruso A., Bush D., Safer H., Patwell D., Prabhakar S., McDougall S., Shimer G., Goyal A., Pietrovski S., Church G.M., Daniels C.J., Mao J.-I., Rice P., Noelling J., Reeve J.N. J. Bacteriol. 179:7135-7155(1997) [PubMed: 9371463] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Delta H.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE000666 Genomic DNA. Translation: AAB85531.1.
PIR	B69005.
RefSeq	NP_276170.1. NC_000916.1.
3D structure databases
ProteinModelPortal	O27114.
ModBase	Search...
Protein-protein interaction databases
STRING	O27114.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1471443.
GenomeReviews	Gene locus MTH_1035 in contig AE000666_GR.
KEGG	mth:MTH1035.
NMPDR	fig|187420.1.peg.1025.
Phylogenomic databases
eggNOG	arNOG08031.
HOGENOM	HBG553299.
OMA	ITQSVVA.
ProtClustDB	PRK08537.
Enzyme and pathway databases
BioCyc	MTHE187420:MTH1035-MONOMER.
Family and domain databases
InterPro	IPR011894. PorC_KorC. IPR019752. Pyrv/ketoisovalerate_OxRed_cat. IPR002869. Pyrv_flavodox_OxRed_cen. [Graphical view]
Gene3D	G3DSA:3.40.920.10. Pyrv_Fd/Flavodoxin_OxRdtase. 1 hit.
KO	K00177.
Pfam	PF01558. POR. 1 hit. [Graphical view]
SUPFAM	SSF53323. Pyrv_Fd/Flavodoxin_OxRdtase. 1 hit.
TIGRFAMs	TIGR02175. PorC_KorC. 1 hit.
ProtoNet	Search...

Entry information

Entry name

KORC_METTH

Accession

Primary (citable) accession number: O27114

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2000
Last sequence update:	January 1, 1998
Last modified:	November 16, 2011
This is version 67 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program