O27113 (KORB_METTH) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
2-oxoglutarate synthase subunit korB
EC=1.2.7.3

Alternative name(s):
2-ketoglutarate oxidoreductase beta chain
Short name=KOR
2-oxoglutarate-ferredoxin oxidoreductase subunit beta

Gene names

Name:	korB
Ordered Locus Names:	MTH_1034

Organism

Methanobacterium thermoautotrophicum (strain Delta H)

Taxonomic identifier

187420 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Methanobacteria › Methanobacteriales › Methanobacteriaceae › Methanothermobacter

Protein attributes

Sequence length	286 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Catalytic activity	2-oxoglutarate + CoA + 2 oxidized ferredoxin = succinyl-CoA + CO2 + 2 reduced ferredoxin + 2 H+.
Subunit structure	Heterotetramer of the korA, korB, korC and korD subunits.

Ontologies

Keywords
Molecular function	Oxidoreductase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular function	2-oxoglutarate synthase activity Inferred from electronic annotation. Source: EC thiamine pyrophosphate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 286	286	2-oxoglutarate synthase subunit korB		PRO_0000099943

Sequences

	Sequence		Length	Mass (Da)
	O27113 [UniParc]. Last modified January 1, 1998. Version 1. Checksum: DB72DBF53B1C8D45	FASTA	286	31,475
	10 20 30 40 50 60 MEKRENPYLR YLRRERLPHI FCAGCGNGIV LNSFFKGMEM AGIDFDNIAM VSGIGCSSRI 70 80 90 100 110 120 PGYVNCDSLH TTHGRPISFA TGLKLGNPSL DVVVFTGDGD AAAIGGNHLI HGARRNIDMT 130 140 150 160 170 180 VICINNSIYG MTGGQISPTF PEGSYGSTAP YGALEDPFDL AELVTAAGAS YVARWTTAHP 190 200 210 220 230 240 LQLANSIKKG LKNRGFSFIE AISQCPTYFG RKNRMRSPVE MMRFMKENSL NRRKALKMEP 250 260 270 280 DEVEGKIIVG EFANRPQPEL CEKICSMVDE KSGRALDMIR SAYRDD

References

[1]

"Complete genome sequence of Methanobacterium thermoautotrophicum deltaH: functional analysis and comparative genomics." Smith D.R., Doucette-Stamm L.A., Deloughery C., Lee H.-M., Dubois J., Aldredge T., Bashirzadeh R., Blakely D., Cook R., Gilbert K., Harrison D., Hoang L., Keagle P., Lumm W., Pothier B., Qiu D., Spadafora R., Vicare R. , Wang Y., Wierzbowski J., Gibson R., Jiwani N., Caruso A., Bush D., Safer H., Patwell D., Prabhakar S., McDougall S., Shimer G., Goyal A., Pietrovski S., Church G.M., Daniels C.J., Mao J.-I., Rice P., Noelling J., Reeve J.N. J. Bacteriol. 179:7135-7155(1997) [PubMed: 9371463] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Delta H.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE000666 Genomic DNA. Translation: AAB85530.1.
PIR	A69005.
RefSeq	NP_276169.1. NC_000916.1.
3D structure databases
ProteinModelPortal	O27113.
ModBase	Search...
Protein-protein interaction databases
STRING	O27113.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1471442.
GenomeReviews	Gene locus MTH_1034 in contig AE000666_GR.
KEGG	mth:MTH1034.
NMPDR	fig|187420.1.peg.1024.
Phylogenomic databases
eggNOG	arNOG04645.
HOGENOM	HBG308756.
OMA	MTGGQGS.
ProtClustDB	PRK05778.
Enzyme and pathway databases
BioCyc	MTHE187420:MTH1034-MONOMER.
Family and domain databases
InterPro	IPR011766. TPP_enzyme-bd_C. [Graphical view]
KO	K00175.
Pfam	PF02775. TPP_enzyme_C. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

KORB_METTH

Accession

Primary (citable) accession number: O27113

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2000
Last sequence update:	January 1, 1998
Last modified:	November 16, 2011
This is version 68 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program