ID   KORA_METTH              Reviewed;         376 AA.
AC   O27112;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 3.
DT   03-MAR-2009, entry version 54.
DE   RecName: Full=2-oxoglutarate synthase subunit korA;
DE            EC=1.2.7.3;
DE   AltName: Full=2-ketoglutarate oxidoreductase alpha chain;
DE            Short=KOR;
DE   AltName: Full=2-oxoglutarate-ferredoxin oxidoreductase subunit alpha;
GN   Name=korA; OrderedLocusNames=MTH_1033;
OS   Methanobacterium thermoautotrophicum.
OC   Archaea; Euryarchaeota; Methanobacteria; Methanobacteriales;
OC   Methanobacteriaceae; Methanothermobacter.
OX   NCBI_TaxID=187420;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Delta H;
RX   MEDLINE=98037514; PubMed=9371463;
RA   Smith D.R., Doucette-Stamm L.A., Deloughery C., Lee H.-M., Dubois J.,
RA   Aldredge T., Bashirzadeh R., Blakely D., Cook R., Gilbert K.,
RA   Harrison D., Hoang L., Keagle P., Lumm W., Pothier B., Qiu D.,
RA   Spadafora R., Vicare R., Wang Y., Wierzbowski J., Gibson R.,
RA   Jiwani N., Caruso A., Bush D., Safer H., Patwell D., Prabhakar S.,
RA   McDougall S., Shimer G., Goyal A., Pietrovski S., Church G.M.,
RA   Daniels C.J., Mao J.-I., Rice P., Noelling J., Reeve J.N.;
RT   "Complete genome sequence of Methanobacterium thermoautotrophicum
RT   deltaH: functional analysis and comparative genomics.";
RL   J. Bacteriol. 179:7135-7155(1997).
CC   -!- CATALYTIC ACTIVITY: 2-oxoglutarate + CoA + 2 oxidized ferredoxin =
CC       succinyl-CoA + CO(2) + 2 reduced ferredoxin + 2 H(+).
CC   -!- SUBUNIT: Heterotetramer of the korA, korB, korC and korD subunits.
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DR   EMBL; AE000666; AAB85529.1; ALT_INIT; Genomic_DNA.
DR   PIR; H69004; H69004.
DR   RefSeq; NP_276168.1; -.
DR   GeneID; 1471441; -.
DR   GenomeReviews; AE000666_GR; MTH_1033.
DR   KEGG; mth:MTH1033; -.
DR   NMPDR; fig|187420.1.peg.1023; -.
DR   HOGENOM; O27112; -.
DR   BioCyc; MTHE187420:MTH1033-MON; -.
DR   BRENDA; 1.2.7.3; 270.
DR   GO; GO:0047553; F:2-oxoglutarate synthase activity; IEA:EC.
DR   GO; GO:0009055; F:electron carrier activity; IEA:InterPro.
DR   GO; GO:0055114; P:oxidation reduction; IEA:UniProtKB-KW.
DR   InterPro; IPR002880; Pyrv_Fd/Flavodoxin_OxRdtase_N.
DR   InterPro; IPR015941; Transketolase_C-like.
DR   Gene3D; G3DSA:3.40.50.920; Transketo_C_like; 1.
DR   Pfam; PF01855; POR_N; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Oxidoreductase.
FT   INIT_MET      1      1       Removed (By similarity).
FT   CHAIN         2    376       2-oxoglutarate synthase subunit korA.
FT                                /FTId=PRO_0000099939.
SQ   SEQUENCE   376 AA;  41377 MW;  2C9E0C53399EAD1F CRC64;
     MTEEYFIQGN DACARGAIKA GCRFFAGYPI TPSTEIAEEM ALLLPREGGV FVQMEDEIGA
     LGAVIGAVWS GVRGMTATSG PGFSLMQEHV GYAAMTETPL VIVNVQRGSP STGQPTMASQ
     SDMMQARWGS HGDYEIIALS PSSVQECFDF TVRAFNLAEE YRVPVMVMGD EIVGHMREKI
     TIPDRVKIRK RRGPSVPPEE FLPFSAPEDG VPEMPAFGDG YRIPVTGLTH DEGGYPDASN
     PEGHHRLVKR LCDKILRHRD RISDVQEELT EDAYITVISY GAPSRSVATA VKMAREDGVR
     AGYLKINTPW PFPETEVRAA AERSGKLLVV EMNLGQMFYE VQRVAAGMAE VELLPKIGGE
     IHRPEEILNM ILKMNR
//