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O27112 (KORA_METTH) Reviewed, UniProtKB/Swiss-Prot

Last modified November 16, 2011. Version 71. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
2-oxoglutarate synthase subunit korA
EC=1.2.7.3
Alternative name(s):
2-ketoglutarate oxidoreductase alpha chain
Short name=KOR
2-oxoglutarate-ferredoxin oxidoreductase subunit alpha
Gene names
Name:korA
Ordered Locus Names:MTH_1033
OrganismMethanobacterium thermoautotrophicum (strain Delta H)
Taxonomic identifier187420 [NCBI]
Taxonomic lineageArchaea › Euryarchaeota › Methanobacteria › Methanobacteriales › Methanobacteriaceae › Methanothermobacter

Protein attributes

Sequence length376 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

2-oxoglutarate + CoA + 2 oxidized ferredoxin = succinyl-CoA + CO2 + 2 reduced ferredoxin + 2 H+.

Subunit structure

Heterotetramer of the korA, korB, korC and korD subunits.

Sequence caution

The sequence AAB85529.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
   Molecular functionOxidoreductase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Molecular function2-oxoglutarate synthase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Initiator methionine11Removed By similarity
Chain2 – 3763752-oxoglutarate synthase subunit korA
PRO_0000099939

Sequences

Sequence LengthMass (Da)Tools
O27112 [UniParc].

Last modified January 23, 2007. Version 3.
Checksum: 2C9E0C53399EAD1F

FASTA37641,377
        10         20         30         40         50         60 
MTEEYFIQGN DACARGAIKA GCRFFAGYPI TPSTEIAEEM ALLLPREGGV FVQMEDEIGA 

        70         80         90        100        110        120 
LGAVIGAVWS GVRGMTATSG PGFSLMQEHV GYAAMTETPL VIVNVQRGSP STGQPTMASQ 

       130        140        150        160        170        180 
SDMMQARWGS HGDYEIIALS PSSVQECFDF TVRAFNLAEE YRVPVMVMGD EIVGHMREKI 

       190        200        210        220        230        240 
TIPDRVKIRK RRGPSVPPEE FLPFSAPEDG VPEMPAFGDG YRIPVTGLTH DEGGYPDASN 

       250        260        270        280        290        300 
PEGHHRLVKR LCDKILRHRD RISDVQEELT EDAYITVISY GAPSRSVATA VKMAREDGVR 

       310        320        330        340        350        360 
AGYLKINTPW PFPETEVRAA AERSGKLLVV EMNLGQMFYE VQRVAAGMAE VELLPKIGGE 

       370 
IHRPEEILNM ILKMNR

« Hide

References

[1]"Complete genome sequence of Methanobacterium thermoautotrophicum deltaH: functional analysis and comparative genomics."
Smith D.R., Doucette-Stamm L.A., Deloughery C., Lee H.-M., Dubois J., Aldredge T., Bashirzadeh R., Blakely D., Cook R., Gilbert K., Harrison D., Hoang L., Keagle P., Lumm W., Pothier B., Qiu D., Spadafora R., Vicare R. expand/collapse author list , Wang Y., Wierzbowski J., Gibson R., Jiwani N., Caruso A., Bush D., Safer H., Patwell D., Prabhakar S., McDougall S., Shimer G., Goyal A., Pietrovski S., Church G.M., Daniels C.J., Mao J.-I., Rice P., Noelling J., Reeve J.N.
J. Bacteriol. 179:7135-7155(1997) [PubMed: 9371463] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Delta H.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE000666 Genomic DNA. Translation: AAB85529.1. Different initiation.
PIRH69004.
RefSeqNP_276168.1. NC_000916.1.

3D structure databases

ProteinModelPortalO27112.
ModBaseSearch...

Protein-protein interaction databases

STRINGO27112.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1471441.
GenomeReviewsGene locus MTH_1033 in contig AE000666_GR.
KEGGmth:MTH1033.
NMPDRfig|187420.1.peg.1023.

Phylogenomic databases

eggNOGarNOG04287.
HOGENOMHBG399087.
OMAVFVQMED.
ProtClustDBPRK08659.

Enzyme and pathway databases

BioCycMTHE187420:MTH1033-MONOMER.

Family and domain databases

InterProIPR002880. Pyrv_Fd/Flavodoxin_OxRdtase_N.
IPR009014. Transketo_C/Pyr-ferredox_oxred.
IPR015941. Transketolase-like_C.
IPR005476. Transketolase_C.
[Graphical view]
Gene3DG3DSA:3.40.50.920. Transketo_C_like. 1 hit.
KOK00174.
PfamPF01855. POR_N. 1 hit.
PF02780. Transketolase_C. 1 hit.
[Graphical view]
SUPFAMSSF52922. Transketo_C_like. 1 hit.
ProtoNetSearch...

Entry information

Entry nameKORA_METTH
AccessionPrimary (citable) accession number: O27112
Entry history
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: January 23, 2007
Last modified: November 16, 2011
This is version 71 of the entry and version 3 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program
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