O27038 (VATC_METTH) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
V-type ATP synthase subunit C

Alternative name(s):
V-ATPase subunit C

Gene names

Name:	atpC
Ordered Locus Names:	MTH_957

Organism

Methanobacterium thermoautotrophicum (strain Delta H)

Taxonomic identifier

187420 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Methanobacteria › Methanobacteriales › Methanobacteriaceae › Methanothermobacter

Protein attributes

Sequence length	385 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Produces ATP from ADP in the presence of a proton gradient across the membrane. HAMAP MF_00314
Sequence similarities	Belongs to the V-ATPase V0D/AC39 subunit family.

Ontologies

Keywords
Biological process	ATP synthesis Hydrogen ion transport Ion transport Transport
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	ATP hydrolysis coupled proton transport Inferred from electronic annotation. Source: InterPro ATP synthesis coupled proton transport Inferred from electronic annotation. Source: InterPro
Cellular component	proton-transporting two-sector ATPase complex, catalytic domain Inferred from electronic annotation. Source: InterPro proton-transporting two-sector ATPase complex, proton-transporting domain Inferred from electronic annotation. Source: InterPro
Molecular function	proton-transporting ATPase activity, rotational mechanism Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 385	385	V-type ATP synthase subunit C HAMAP MF_00314		PRO_0000119368

Sequences

	Sequence		Length	Mass (Da)
	O27038 [UniParc]. Last modified January 1, 1998. Version 1. Checksum: 31A31560E5132680	FASTA	385	42,441
	10 20 30 40 50 60 MADSITTIVT ALGFPSIESF IGVLLLGGAI IGAIVVIATI RPILDLFPFA YPNARVRARI 70 80 90 100 110 120 GRLLNEKQLS EILETESMEE FKNYLRGLPD YAKYIDRFPI EKALESQLAE TYEMVSQIAP 130 140 150 160 170 180 ASIRDPFRAN LKRWDVRNIK SLITAKAAGL SAEETVNLLV PGGEVYEIIE GLADASSVQE 190 200 210 220 230 240 VVTGLEATEY AGVLEDALSG YEETGMLLPI EAALDRKFLE GLIRTVGSPS DDNTKILHTY 250 260 270 280 290 300 FGTMVDISNL KIILRAKADG LSYDDISPYI VPHGYQIREW KLKDLMESED VSGVVSGLEG 310 320 330 340 350 360 TDYGQMLSEA LSEYTSTGSV AVFERVLEDN LNRMARNFAL KKPFGVGPMI GFLSRKEVEV 370 380 KNLKVIARSK REPGFPEAMV KEMLA

References

[1]

"Complete genome sequence of Methanobacterium thermoautotrophicum deltaH: functional analysis and comparative genomics." Smith D.R., Doucette-Stamm L.A., Deloughery C., Lee H.-M., Dubois J., Aldredge T., Bashirzadeh R., Blakely D., Cook R., Gilbert K., Harrison D., Hoang L., Keagle P., Lumm W., Pothier B., Qiu D., Spadafora R., Vicare R. , Wang Y., Wierzbowski J., Gibson R., Jiwani N., Caruso A., Bush D., Safer H., Patwell D., Prabhakar S., McDougall S., Shimer G., Goyal A., Pietrovski S., Church G.M., Daniels C.J., Mao J.-I., Rice P., Noelling J., Reeve J.N. J. Bacteriol. 179:7135-7155(1997) [PubMed: 9371463] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Delta H.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE000666 Genomic DNA. Translation: AAB85453.1.
PIR	A69228.
RefSeq	NP_276092.1. NC_000916.1.
3D structure databases
ProteinModelPortal	O27038.
ModBase	Search...
Protein-protein interaction databases
IntAct	O27038. 2 interactions.
STRING	O27038.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1471365.
GenomeReviews	Gene locus MTH_957 in contig AE000666_GR.
KEGG	mth:MTH957.
NMPDR	fig|187420.1.peg.947.
Phylogenomic databases
eggNOG	arNOG05775.
HOGENOM	HBG541187.
OMA	GVDLIEY.
ProtClustDB	PRK01198.
Enzyme and pathway databases
BioCyc	MTHE187420:MTH957-MONOMER.
Family and domain databases
HAMAP	MF_00314. ATP_synth_C_arch. [Tree]
InterPro	IPR014272. ATPase_A1-cplx_csu. IPR002843. ATPase_V0/A0-cplx_csu/dsu. [Graphical view]
KO	K02119.
Pfam	PF01992. vATP-synt_AC39. 1 hit. [Graphical view]
SUPFAM	SSF103486. ATPase_V0/A0_c/d. 1 hit.
TIGRFAMs	TIGR02923. AhaC. 1 hit.
ProtoNet	Search...

Entry information

Entry name

VATC_METTH

Accession

Primary (citable) accession number: O27038

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 24, 2001
Last sequence update:	January 1, 1998
Last modified:	November 16, 2011
This is version 72 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program