O27035 (VATB_METTH) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
V-type ATP synthase beta chain

Alternative name(s):
V-ATPase subunit B

Gene names

Name:	atpB
Ordered Locus Names:	MTH_954

Organism

Methanobacterium thermoautotrophicum (strain Delta H)

Taxonomic identifier

187420 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Methanobacteria › Methanobacteriales › Methanobacteriaceae › Methanothermobacter

Protein attributes

Sequence length	463 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit. HAMAP MF_00310
Sequence similarities	Belongs to the ATPase alpha/beta chains family.
Sequence caution	The sequence AAB85450.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
Biological process	ATP synthesis Hydrogen ion transport Ion transport Transport
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	ATP hydrolysis coupled proton transport Inferred from electronic annotation. Source: InterPro ATP synthesis coupled proton transport Inferred from electronic annotation. Source: InterPro
Cellular component	proton-transporting two-sector ATPase complex, catalytic domain Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: InterPro hydrogen ion transporting ATP synthase activity, rotational mechanism Inferred from electronic annotation. Source: InterPro proton-transporting ATPase activity, rotational mechanism Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 463	463	V-type ATP synthase beta chain HAMAP MF_00310		PRO_0000144658

Sequences

	Sequence		Length	Mass (Da)
	O27035 [UniParc]. Last modified January 24, 2001. Version 2. Checksum: E0CA490EC9B83206	FASTA	463	51,665
	10 20 30 40 50 60 MNVNIKTREY TTVTEVSGPL MIVEGVEGVA YSEIVEIETP TGEKRRGQVL EVREDLAVVQ 70 80 90 100 110 120 VFEGTSDLNT ETTKIRFTGE TAKIGVSLDM MGRIFDGTGK PIDGGPEIIP EKELDINGSP 130 140 150 160 170 180 MNPAAREFPA EFIQTGISTI DGMNTLVRGQ KLPIFSGSGL PHNELAAQIA RQAKVLAEES 190 200 210 220 230 240 EFAVIFAAMG ITHEEANYFM RDFERTGALE RVTVFMNLAD DPAIERIITP RMALTTAEYF 250 260 270 280 290 300 AFEHDMHVLV ILTDLTNYCE ALREISAARE EVPGRRGYPG YMYTDLASLY ERAGRIVGKE 310 320 330 340 350 360 GSITQMPILV MPQDDITHPI PDLTGYITEG QIVLSRDLHR KGIYPPVDVL PSLSRLMSGG 370 380 390 400 410 420 IGEGRTREDH SGVSDQLYSA YAEGRDLRDL MAVVGEEALT ERDRKFLKFA DEFEKRFITQ 430 440 450 460 ARDEDRSIEE TLNLGWELLS LLPRSELKRV REEHIPKYLP GAE

References

[1]

"Complete genome sequence of Methanobacterium thermoautotrophicum deltaH: functional analysis and comparative genomics." Smith D.R., Doucette-Stamm L.A., Deloughery C., Lee H.-M., Dubois J., Aldredge T., Bashirzadeh R., Blakely D., Cook R., Gilbert K., Harrison D., Hoang L., Keagle P., Lumm W., Pothier B., Qiu D., Spadafora R., Vicare R. , Wang Y., Wierzbowski J., Gibson R., Jiwani N., Caruso A., Bush D., Safer H., Patwell D., Prabhakar S., McDougall S., Shimer G., Goyal A., Pietrovski S., Church G.M., Daniels C.J., Mao J.-I., Rice P., Noelling J., Reeve J.N. J. Bacteriol. 179:7135-7155(1997) [PubMed: 9371463] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Delta H.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE000666 Genomic DNA. Translation: AAB85450.1. Different initiation.
PIR	F69227.
RefSeq	NP_276089.1. NC_000916.1.
3D structure databases
ProteinModelPortal	O27035.
SMR	O27035. Positions 18-461.
ModBase	Search...
Protein-protein interaction databases
IntAct	O27035. 1 interaction.
STRING	O27035.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1471362.
GenomeReviews	Gene locus MTH_954 in contig AE000666_GR.
KEGG	mth:MTH954.
NMPDR	fig|187420.1.peg.944.
Phylogenomic databases
eggNOG	arNOG04087.
HOGENOM	HBG565875.
OMA	VVFINLA.
PhylomeDB	O27035.
ProtClustDB	PRK04196.
Enzyme and pathway databases
BioCyc	MTHE187420:MTH954-MONOMER.
Family and domain databases
HAMAP	MF_00310. ATP_synth_B_arch. [Tree]
InterPro	IPR020003. ATPase_a/bsu_AS. IPR005724. ATPase_A1-cplx_bsu. IPR018118. ATPase_F1/A1-cplx_a/bsu_N. IPR000793. ATPase_F1/V1/A1-cplx_a/bsu_C. IPR004100. ATPase_F1/V1/A1-cplx_a/bsu_N. IPR000194. ATPase_F1/V1/A1_a/bsu_nucl-bd. IPR024034. ATPase_F1_bsu/V1_C. IPR022879. V-ATPase_su_B/beta. [Graphical view]
Gene3D	G3DSA:1.10.1140.10. G3DSA:1.10.1140.10. 1 hit.
KO	K02118.
Pfam	PF00006. ATP-synt_ab. 1 hit. PF00306. ATP-synt_ab_C. 1 hit. PF02874. ATP-synt_ab_N. 1 hit. [Graphical view]
SUPFAM	SSF47917. ATPase_a/b_C. 1 hit. SSF50615. ATPase_a/b_N. 1 hit.
TIGRFAMs	TIGR01041. ATP_syn_B_arch. 1 hit.
PROSITE	PS00152. ATPASE_ALPHA_BETA. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

VATB_METTH

Accession

Primary (citable) accession number: O27035

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 24, 2001
Last sequence update:	January 24, 2001
Last modified:	November 16, 2011
This is version 80 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program