Skip Header

Contribute Send feedback
Read comments (?) or add your own

O26957 (SUHB_METTH) Reviewed, UniProtKB/Swiss-Prot

Last modified November 16, 2011. Version 81. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Inositol-1-monophosphatase
Short name=I-1-Pase
Short name=IMPase
Short name=Inositol-1-phosphatase
EC=3.1.3.25
Gene names
Name:suhB
Ordered Locus Names:MTH_871
OrganismMethanobacterium thermoautotrophicum (strain Delta H)
Taxonomic identifier187420 [NCBI]
Taxonomic lineageArchaea › Euryarchaeota › Methanobacteria › Methanobacteriales › Methanobacteriaceae › Methanothermobacter

Protein attributes

Sequence length280 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Myo-inositol phosphate + H2O = myo-inositol + phosphate.

Cofactor

Magnesium By similarity.

Sequence similarities

Belongs to the inositol monophosphatase family.

Ontologies

Keywords
   LigandMagnesium
Metal-binding
   Molecular functionHydrolase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Molecular functioninositol monophosphate 1-phosphatase activity

Inferred from electronic annotation. Source: EC

metal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 280280Inositol-1-monophosphatase
PRO_0000142581

Sites

Metal binding731Magnesium 1 By similarity
Metal binding941Magnesium 1 By similarity
Metal binding941Magnesium 2 By similarity
Metal binding961Magnesium 1; via carbonyl oxygen By similarity
Metal binding971Magnesium 2 By similarity
Metal binding2261Magnesium 2 By similarity
Binding site971Substrate By similarity
Binding site2191Substrate By similarity

Sequences

Sequence LengthMass (Da)Tools
O26957 [UniParc].

Last modified January 1, 1998. Version 1.
Checksum: F0AE435970AED882

FASTA28030,173
        10         20         30         40         50         60 
MEESDIYYWK GVAVRMAEQV ERAVSPLVGT EDAGEIIKMG ADGTPTKLID LVAEDEAVGV 

        70         80         90        100        110        120 
LESTGRPVTI ISEEIGVLHI NSEGDEPGII FVVDPLDGTS NAIRNIPFYG ISVAVAERHP 

       130        140        150        160        170        180 
DGAAPTLNNV LMGFVKNFAT GDLYWAIKGQ GAFLNEKAIS SSSQSSLDRT SLGAFIYGTR 

       190        200        210        220        230        240 
FRRVDSICRV IRRMRILGSV ALELAYVASG SYDAFMDLRE NLRIVDIAAS KLIVEEAGGV 

       250        260        270        280 
VTNERGGEID GLLNVKARTS LVAAGNLELH EKIMQTLEVI

« Hide

References

[1]"Complete genome sequence of Methanobacterium thermoautotrophicum deltaH: functional analysis and comparative genomics."
Smith D.R., Doucette-Stamm L.A., Deloughery C., Lee H.-M., Dubois J., Aldredge T., Bashirzadeh R., Blakely D., Cook R., Gilbert K., Harrison D., Hoang L., Keagle P., Lumm W., Pothier B., Qiu D., Spadafora R., Vicare R. expand/collapse author list , Wang Y., Wierzbowski J., Gibson R., Jiwani N., Caruso A., Bush D., Safer H., Patwell D., Prabhakar S., McDougall S., Shimer G., Goyal A., Pietrovski S., Church G.M., Daniels C.J., Mao J.-I., Rice P., Noelling J., Reeve J.N.
J. Bacteriol. 179:7135-7155(1997) [PubMed: 9371463] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Delta H.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE000666 Genomic DNA. Translation: AAB85369.1.
PIRD69216.
RefSeqNP_276008.1. NC_000916.1.

3D structure databases

ProteinModelPortalO26957.
ModBaseSearch...

Protein-protein interaction databases

STRINGO26957.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1471279.
GenomeReviewsGene locus MTH_871 in contig AE000666_GR.
KEGGmth:MTH871.
NMPDRfig|187420.1.peg.863.

Phylogenomic databases

eggNOGarNOG05430.
HOGENOMHBG730251.
OMADIRNYVR.
ProtClustDBPRK12676.

Enzyme and pathway databases

BioCycMTHE187420:MTH871-MONOMER.

Family and domain databases

InterProIPR020583. Inositol_monoP_metal-BS.
IPR000760. Inositol_monophosphatase.
IPR020550. Inositol_monophosphatase_CS.
[Graphical view]
KOK01092.
PANTHERPTHR20854. Inositol_P. 1 hit.
PfamPF00459. Inositol_P. 1 hit.
[Graphical view]
PRINTSPR00377. IMPHPHTASES.
PROSITEPS00629. IMP_1. 1 hit.
PS00630. IMP_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSUHB_METTH
AccessionPrimary (citable) accession number: O26957
Entry history
Integrated into UniProtKB/Swiss-Prot: January 23, 2002
Last sequence update: January 1, 1998
Last modified: November 16, 2011
This is version 81 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents