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Protein
Submitted name:

Heavy-metal transporting CPx-type ATPase

Gene

MTH_755

Organism
Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H) (Methanobacterium thermoautotrophicum)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Heavy-metal transporting CPx-type ATPaseImported
Gene namesi
Ordered Locus Names:MTH_755Imported
OrganismiMethanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H) (Methanobacterium thermoautotrophicum)Imported
Taxonomic identifieri187420 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanobacteriaMethanobacterialesMethanobacteriaceaeMethanothermobacter
Proteomesi
  • UP000005223 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei42 – 60HelicalSequence analysisAdd BLAST19
Transmembranei72 – 90HelicalSequence analysisAdd BLAST19
Transmembranei102 – 123HelicalSequence analysisAdd BLAST22
Transmembranei129 – 148HelicalSequence analysisAdd BLAST20
Transmembranei282 – 304HelicalSequence analysisAdd BLAST23
Transmembranei316 – 343HelicalSequence analysisAdd BLAST28
Transmembranei619 – 637HelicalSequence analysisAdd BLAST19
Transmembranei643 – 662HelicalSequence analysisAdd BLAST20

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Interactioni

Protein-protein interaction databases

STRINGi187420.MTH755.

Structurei

3D structure databases

ProteinModelPortaliO26849.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini138 – 356E1-E2_ATPaseInterPro annotationAdd BLAST219

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiarCOG01576. Archaea.
COG2217. LUCA.
KOiK01533.
OMAiARKPGMM.

Family and domain databases

Gene3Di2.70.150.10. 1 hit.
3.40.1110.10. 1 hit.
3.40.50.1000. 2 hits.
InterProiIPR023299. ATPase_P-typ_cyto_domN.
IPR018303. ATPase_P-typ_P_site.
IPR008250. ATPase_P-typ_transduc_dom_A.
IPR023214. HAD-like_dom.
IPR027256. P-typ_ATPase_IB.
IPR001757. P_typ_ATPase.
[Graphical view]
PfamiPF00122. E1-E2_ATPase. 1 hit.
[Graphical view]
SUPFAMiSSF56784. SSF56784. 2 hits.
TIGRFAMsiTIGR01525. ATPase-IB_hvy. 1 hit.
TIGR01494. ATPase_P-type. 1 hit.
PROSITEiPS00154. ATPASE_E1_E2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O26849-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGRQKDHEKG PGEIMESHGH HEKKGKMMDS HGHHEEDYRR RFIICLLMTI
60 70 80 90 100
PVILLGELPT GNVLFSFEGS EFLVLILSSA IFLYGGYPFL RGSLRELSSR
110 120 130 140 150
TPGMMTLIAV AITVAYTYSL GVILGLEGMV FFVELVTLID VMLLGHWIEM
160 170 180 190 200
RSIMSASGAV ERLAGLLPRR AHLVVDGKVE DVDVSTLKPG DIVVVRSGER
210 220 230 240 250
VPSDGTVIRG ESHVNESLLT GESRPIKKVP GDGVIGGSIN TGGSLTVEVE
260 270 280 290 300
RVGEESFISQ IIELVGRAQE GRTRTQVLAD KAAFWLTSIA LLGGLLTFIA
310 320 330 340 350
WSWLGMDVFF SLERAVTLMV TACPHALGLA IPLVIAVSTA ISAGRGILIR
360 370 380 390 400
NRESFENARD PDVVVFDKTG TLTMGELGIT DVISFDPEMD EGEILSYAAA
410 420 430 440 450
VESGSSHPIA RGIVEAVAEV LPVENFNSLE GRGVMGHVNG SVVKVLSYGY
460 470 480 490 500
TEELGFSISD PRVDELIGQA KTTVFVIVDD ELRGCIALAD MIRPEAREAV
510 520 530 540 550
GILRSRGVRC LMLTGDSSAV AGWVASEVGI DDYMAELIPI EKYDEIRKLQ
560 570 580 590 600
EEGLRVVMVG DGVNDAPALV QADIGVAIGA GTDVAIESAD VVLVRSNPLD
610 620 630 640 650
VVDLMDLAAA TYSKMKENLI WATGYNVIAL PLAAGVLYGQ GIILSPAMGA
660 670
ILMSLSTVIV ALNARTFSFS GQSGR
Length:675
Mass (Da):72,338
Last modified:January 1, 1998 - v1
Checksum:i56A5D4C175C0CC6F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000666 Genomic DNA. Translation: AAB85258.1.
PIRiH69200.
RefSeqiWP_010876393.1. NC_000916.1.

Genome annotation databases

EnsemblBacteriaiAAB85258; AAB85258; MTH_755.
GeneIDi1471163.
KEGGimth:MTH_755.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000666 Genomic DNA. Translation: AAB85258.1.
PIRiH69200.
RefSeqiWP_010876393.1. NC_000916.1.

3D structure databases

ProteinModelPortaliO26849.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi187420.MTH755.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAB85258; AAB85258; MTH_755.
GeneIDi1471163.
KEGGimth:MTH_755.

Phylogenomic databases

eggNOGiarCOG01576. Archaea.
COG2217. LUCA.
KOiK01533.
OMAiARKPGMM.

Family and domain databases

Gene3Di2.70.150.10. 1 hit.
3.40.1110.10. 1 hit.
3.40.50.1000. 2 hits.
InterProiIPR023299. ATPase_P-typ_cyto_domN.
IPR018303. ATPase_P-typ_P_site.
IPR008250. ATPase_P-typ_transduc_dom_A.
IPR023214. HAD-like_dom.
IPR027256. P-typ_ATPase_IB.
IPR001757. P_typ_ATPase.
[Graphical view]
PfamiPF00122. E1-E2_ATPase. 1 hit.
[Graphical view]
SUPFAMiSSF56784. SSF56784. 2 hits.
TIGRFAMsiTIGR01525. ATPase-IB_hvy. 1 hit.
TIGR01494. ATPase_P-type. 1 hit.
PROSITEiPS00154. ATPASE_E1_E2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiO26849_METTH
AccessioniPrimary (citable) accession number: O26849
Entry historyi
Integrated into UniProtKB/TrEMBL: January 1, 1998
Last sequence update: January 1, 1998
Last modified: November 2, 2016
This is version 107 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.