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Reviewed, UniProtKB/Swiss-Prot O26807 (MSRB_METTH)

Last modified June 16, 2009. Version 58. Feed History...

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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Peptide methionine sulfoxide reductase msrB
    EC=1.8.4.12
Alternative name(s):
    Peptide-methionine (R)-S-oxide reductase
Gene names
Name: msrB
Ordered Locus Names: MTH_711
OrganismMethanobacterium thermoautotrophicum [Complete proteome] [HAMAP]
Taxonomic identifier187420 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaMethanobacteriaMethanobacterialesMethanobacteriaceaeMethanothermobacter

Protein attributes

Sequence length151 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceEvidence at protein level.

General annotation (Comments)

Catalytic activity

Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (R)-S-oxide + thioredoxin. HAMAP MF_01400

Cofactor

Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein By similarity.

Sequence similarities

Belongs to the msrB Met sulfoxide reductase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 151151Peptide methionine sulfoxide reductase msrB HAMAP MF_01400
PRO_0000140320

Sites

Active site1361Nucleophile By similarity
Metal binding641Zinc By similarity
Metal binding671Zinc By similarity
Metal binding1131Zinc By similarity
Metal binding1161Zinc By similarity

Sequences

Sequence LengthMass (Da)Tools
O26807-1 [UniParc].

Last modified January 1, 1998. Version 1.
Checksum: 8D11C52CEB186033

FASTA15117,303
        10         20         30         40         50         60 
MKDRIPIFSV AKNRVEMVER IELSDDEWRE ILDPEAFRVA RKAGTEPPFT GKYHDLHDDG 

        70         80         90        100        110        120 
IYRCICCGTD LFDSETKFDS GTGWPSFYDV VSEHNIKLRE DRSLGMVRCE VLCARCDAHL 

       130        140        150 
GHVFDDGPRP TGKRYCMNSA ALKFIPRDQI G 

« Hide

References

[1]"Complete genome sequence of Methanobacterium thermoautotrophicum deltaH: functional analysis and comparative genomics."
Smith D.R., Doucette-Stamm L.A., Deloughery C., Lee H.-M., Dubois J., Aldredge T., Bashirzadeh R., Blakely D., Cook R., Gilbert K., Harrison D., Hoang L., Keagle P., Lumm W., Pothier B., Qiu D., Spadafora R., Vicare R. expand/collapse author list , Wang Y., Wierzbowski J., Gibson R., Jiwani N., Caruso A., Bush D., Safer H., Patwell D., Prabhakar S., McDougall S., Shimer G., Goyal A., Pietrovski S., Church G.M., Daniels C.J., Mao J.-I., Rice P., Noelling J., Reeve J.N.
J. Bacteriol. 179:7135-7155(1997) [PubMed: 9371463] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Delta H.

Cross-references

Sequence databases

AE000666 Genomic DNA. Translation: AAB85216.1.
PIRA69195.
RefSeqNP_275854.1.

3D structure databases

EntryMethodResolution (Å)ChainPositionsPDBsum
2K8DNMR-A1-151[»]
ModBaseSearch...

Genome annotation databases

GeneID1470672.
GenomeReviewsGene locus MTH_711 in contig AE000666_GR.
KEGGmth:MTH711.
NMPDRfig|187420.1.peg.709.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMO26807.
OMAO26807. MVERIEL.

Enzyme and pathway databases

BioCycMTHE187420:MTH711-MON.
BRENDA1.8.4.12. 270.

Family and domain databases

HAMAPMF_01400.
[Tree]
InterProIPR002579. Methionine_sulphoxide_MsrB.
[Graphical view]
Gene3DG3DSA:2.170.150.20. MsrB. 1 hit.
PfamPF01641. SelR. 1 hit.
[Graphical view]
ProDomPD004057. DUF25. 1 hit.
[Graphical view] [Entries sharing at least one domain]
TIGRFAMsTIGR00357. MsrB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameMSRB_METTH
AccessionPrimary (citable) accession number: O26807
Entry history
Integrated into UniProtKB/Swiss-Prot: May 2, 2002
Last sequence update: January 1, 1998
Last modified: June 16, 2009
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents