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O26807 (MSRB_METTH) Reviewed, UniProtKB/Swiss-Prot

Last modified November 16, 2011. Version 78. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Peptide methionine sulfoxide reductase MsrB
EC=1.8.4.12
Alternative name(s):
Peptide-methionine (R)-S-oxide reductase
Gene names
Name:msrB
Ordered Locus Names:MTH_711
OrganismMethanobacterium thermoautotrophicum (strain Delta H)
Taxonomic identifier187420 [NCBI]
Taxonomic lineageArchaea › Euryarchaeota › Methanobacteria › Methanobacteriales › Methanobacteriaceae › Methanothermobacter

Protein attributes

Sequence length151 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Catalytic activity

Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (R)-S-oxide + thioredoxin. HAMAP MF_01400

Cofactor

Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein By similarity.

Sequence similarities

Belongs to the MsrB Met sulfoxide reductase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 151151Peptide methionine sulfoxide reductase MsrB HAMAP MF_01400
PRO_0000140320

Sites

Active site1361Nucleophile By similarity
Metal binding641Zinc By similarity
Metal binding671Zinc By similarity
Metal binding1131Zinc By similarity
Metal binding1161Zinc By similarity

Secondary structure

1 ....................... 151
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
O26807 [UniParc].

Last modified January 1, 1998. Version 1.
Checksum: 8D11C52CEB186033

FASTA15117,303
        10         20         30         40         50         60 
MKDRIPIFSV AKNRVEMVER IELSDDEWRE ILDPEAFRVA RKAGTEPPFT GKYHDLHDDG 

        70         80         90        100        110        120 
IYRCICCGTD LFDSETKFDS GTGWPSFYDV VSEHNIKLRE DRSLGMVRCE VLCARCDAHL 

       130        140        150 
GHVFDDGPRP TGKRYCMNSA ALKFIPRDQI G

« Hide

References

[1]"Complete genome sequence of Methanobacterium thermoautotrophicum deltaH: functional analysis and comparative genomics."
Smith D.R., Doucette-Stamm L.A., Deloughery C., Lee H.-M., Dubois J., Aldredge T., Bashirzadeh R., Blakely D., Cook R., Gilbert K., Harrison D., Hoang L., Keagle P., Lumm W., Pothier B., Qiu D., Spadafora R., Vicare R. expand/collapse author list , Wang Y., Wierzbowski J., Gibson R., Jiwani N., Caruso A., Bush D., Safer H., Patwell D., Prabhakar S., McDougall S., Shimer G., Goyal A., Pietrovski S., Church G.M., Daniels C.J., Mao J.-I., Rice P., Noelling J., Reeve J.N.
J. Bacteriol. 179:7135-7155(1997) [PubMed: 9371463] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Delta H.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE000666 Genomic DNA. Translation: AAB85216.1.
PIRA69195.
RefSeqNP_275854.1. NC_000916.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
2K8DNMR-A1-151[»]
ProteinModelPortalO26807.
SMRO26807. Positions 21-147.
ModBaseSearch...

Protein-protein interaction databases

STRINGO26807.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1470672.
GenomeReviewsGene locus MTH_711 in contig AE000666_GR.
KEGGmth:MTH711.
NMPDRfig|187420.1.peg.709.

Phylogenomic databases

eggNOGarNOG10043.
HOGENOMHBG715255.
OMAPSFWDVY.
PhylomeDBO26807.
ProtClustDBPRK00222.

Enzyme and pathway databases

BioCycMTHE187420:MTH711-MONOMER.

Family and domain databases

HAMAPMF_01400. MsrB.
[Tree]
InterProIPR002579. Methionine_sulphoxide_MsrB.
IPR011057. Mss4-like.
[Graphical view]
Gene3DG3DSA:2.170.150.20. MsrB. 1 hit.
KOK07305.
PfamPF01641. SelR. 1 hit.
[Graphical view]
SUPFAMSSF51316. Mss4_like. 1 hit.
TIGRFAMsTIGR00357. TIGR00357. 1 hit.
ProtoNetSearch...

Entry information

Entry nameMSRB_METTH
AccessionPrimary (citable) accession number: O26807
Entry history
Integrated into UniProtKB/Swiss-Prot: May 2, 2002
Last sequence update: January 1, 1998
Last modified: November 16, 2011
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

SIMILARITY comments

Index of protein domains and families

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