O26631 (Y531_METTH) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Uncharacterized protein MTH_531

Gene names

Ordered Locus Names:

MTH_531

Organism

Methanobacterium thermoautotrophicum (strain Delta H)

Taxonomic identifier

187420 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Methanobacteria › Methanobacteriales › Methanobacteriaceae › Methanothermobacter

Protein attributes

Sequence length	312 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the MurCDEF family.

Ontologies

Keywords
Ligand	ATP-binding Nucleotide-binding
Molecular function	Ligase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	biosynthetic process Inferred from electronic annotation. Source: InterPro cell division Inferred from electronic annotation. Source: InterPro regulation of cell shape Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW UDP-N-acetylmuramoylalanine-D-glutamate ligase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 312	312	Uncharacterized protein MTH_531		PRO_0000101710
Regions
	Nucleotide binding	112 – 118	7	ATP Potential

Sequences

	Sequence		Length	Mass (Da)
	O26631 [UniParc]. Last modified January 1, 1998. Version 1. Checksum: 4AA7AFEF0A793002	FASTA	312	34,743
	10 20 30 40 50 60 MIRNMKVLVI GAGNAGRPAA RLLNHLNNRV LVNDVRELHE LPLKAQKRIA EMEDEGVMFR 70 80 90 100 110 120 FGGHSMEDIL WADAVFISPN IPQDAPVRKM VREAGDLVHI TTSDIGRTLN ELIGLPMVGV 130 140 150 160 170 180 AGTDGKTTTT NMIDHILSSR YRTVSFSSLQ DSLVIEGLVE LVVNGDIDDR DLAVFELPHG 190 200 210 220 230 240 TIRMAEGLEL SAGVVTNLTP DHMDEFSNYD EYIERNFSIK DLMAPGGVLA LCGDDPVISS 250 260 270 280 290 300 LLDDLEVENV VYGVGERRTV EFMGRRFMLS QYPGQGLRYR AEGTCRIHLH PECIRDTDSH 310 LQHLRSPQLQ ET

References

[1]

"Complete genome sequence of Methanobacterium thermoautotrophicum deltaH: functional analysis and comparative genomics." Smith D.R., Doucette-Stamm L.A., Deloughery C., Lee H.-M., Dubois J., Aldredge T., Bashirzadeh R., Blakely D., Cook R., Gilbert K., Harrison D., Hoang L., Keagle P., Lumm W., Pothier B., Qiu D., Spadafora R., Vicare R. , Wang Y., Wierzbowski J., Gibson R., Jiwani N., Caruso A., Bush D., Safer H., Patwell D., Prabhakar S., McDougall S., Shimer G., Goyal A., Pietrovski S., Church G.M., Daniels C.J., Mao J.-I., Rice P., Noelling J., Reeve J.N. J. Bacteriol. 179:7135-7155(1997) [PubMed: 9371463] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Delta H.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE000666 Genomic DNA. Translation: AAB85037.1.
PIR	B69170.
RefSeq	NP_275674.1. NC_000916.1.
3D structure databases
ProteinModelPortal	O26631.
ModBase	Search...
Protein-protein interaction databases
STRING	O26631.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1470492.
GenomeReviews	Gene locus MTH_531 in contig AE000666_GR.
KEGG	mth:MTH531.
NMPDR	fig|187420.1.peg.529.
Phylogenomic databases
eggNOG	arNOG05615.
Enzyme and pathway databases
BioCyc	MTHE187420:MTH531-MONOMER.
Family and domain databases
InterPro	IPR013221. Mur_ligase_cen. IPR016040. NAD(P)-bd_dom. IPR005762. UDP-N-AcMur-Glu_ligase. [Graphical view]
Gene3D	G3DSA:3.40.1190.10. Mur_ligase_cen. 1 hit. G3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
KO	K01925.
PANTHER	PTHR23135:SF2. PTHR23135:SF2. 1 hit.
Pfam	PF08245. Mur_ligase_M. 1 hit. [Graphical view]
SUPFAM	SSF53623. Mur_ligase_cen. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Y531_METTH

Accession

Primary (citable) accession number: O26631

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 15, 1998
Last sequence update:	January 1, 1998
Last modified:	November 16, 2011
This is version 62 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program