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Protein
Submitted name:

Sensory transduction histidine kinase

Gene

MTH_444

Organism
Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H) (Methanobacterium thermoautotrophicum)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

KinaseImported, Transferase

Enzyme and pathway databases

BioCyciMTHE187420:GJNM-444-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Sensory transduction histidine kinaseImported
Gene namesi
Ordered Locus Names:MTH_444Imported
OrganismiMethanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H) (Methanobacterium thermoautotrophicum)Imported
Taxonomic identifieri187420 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanobacteriaMethanobacterialesMethanobacteriaceaeMethanothermobacter
Proteomesi
  • UP000005223 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei38 – 6427HelicalSequence analysisAdd
BLAST
Transmembranei76 – 9318HelicalSequence analysisAdd
BLAST
Transmembranei105 – 12218HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Interactioni

Protein-protein interaction databases

STRINGi187420.MTH444.

Structurei

3D structure databases

ProteinModelPortaliO26544.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini158 – 372215Histidine kinaseInterPro annotationAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili128 – 15528Sequence analysisAdd
BLAST

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiarCOG07605. Archaea.
COG0642. LUCA.
KOiK02486.
OMAiCTVALEW.

Family and domain databases

Gene3Di1.10.287.130. 1 hit.
3.30.565.10. 1 hit.
InterProiIPR003594. HATPase_C.
IPR005467. His_kinase_dom.
IPR003661. HisK_dim/P.
IPR004358. Sig_transdc_His_kin-like_C.
[Graphical view]
PfamiPF02518. HATPase_c. 1 hit.
PF00512. HisKA. 1 hit.
[Graphical view]
PRINTSiPR00344. BCTRLSENSOR.
SMARTiSM00387. HATPase_c. 1 hit.
SM00388. HisKA. 1 hit.
[Graphical view]
SUPFAMiSSF47384. SSF47384. 1 hit.
SSF55874. SSF55874. 1 hit.
PROSITEiPS50109. HIS_KIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O26544-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEFFAVSLDS HVFSHIKEIF LYNHNQKFYV VMMKHDDVLM ILAAAALMFS
60 70 80 90 100
FSWVHGMLLV LPLLAIPQLS SRTLKWGVLV LAVFVALLIL QPMTRAVGLN
110 120 130 140 150
ISDELFRLVL LLLFTFMVAL LIERIEKVRS LRELNLELKK QAEKLEDANK
160 170 180 190 200
ELEAFAYSVS HDLRVPLRAI DGFSRILVED YEDKLDDEGV RILGIIRDNT
210 220 230 240 250
RKMGQLIDDI LLLSRAGRQE MNLAMLDMRE LAESTYRELA SQEEGRSIEF
260 270 280 290 300
SVADLPPAMA DRALMGQVMG NLLSNAIKFT RDRDPAVIEV GYMDGGDEHT
310 320 330 340 350
YYVKDNGAGF DMKYASKLFG LFQRLHSQEE FEGTGVGLSI VQRIIKRHGG
360 370
RVWGEGKVDG GATIYFTLPK VVK
Length:373
Mass (Da):42,263
Last modified:January 1, 1998 - v1
Checksum:iA338D584484381D2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000666 Genomic DNA. Translation: AAB84950.1.
PIRiA69158.
RefSeqiWP_010876083.1. NC_000916.1.

Genome annotation databases

EnsemblBacteriaiAAB84950; AAB84950; MTH_444.
GeneIDi24853596.
KEGGimth:MTH_444.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000666 Genomic DNA. Translation: AAB84950.1.
PIRiA69158.
RefSeqiWP_010876083.1. NC_000916.1.

3D structure databases

ProteinModelPortaliO26544.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi187420.MTH444.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAB84950; AAB84950; MTH_444.
GeneIDi24853596.
KEGGimth:MTH_444.

Phylogenomic databases

eggNOGiarCOG07605. Archaea.
COG0642. LUCA.
KOiK02486.
OMAiCTVALEW.

Enzyme and pathway databases

BioCyciMTHE187420:GJNM-444-MONOMER.

Family and domain databases

Gene3Di1.10.287.130. 1 hit.
3.30.565.10. 1 hit.
InterProiIPR003594. HATPase_C.
IPR005467. His_kinase_dom.
IPR003661. HisK_dim/P.
IPR004358. Sig_transdc_His_kin-like_C.
[Graphical view]
PfamiPF02518. HATPase_c. 1 hit.
PF00512. HisKA. 1 hit.
[Graphical view]
PRINTSiPR00344. BCTRLSENSOR.
SMARTiSM00387. HATPase_c. 1 hit.
SM00388. HisKA. 1 hit.
[Graphical view]
SUPFAMiSSF47384. SSF47384. 1 hit.
SSF55874. SSF55874. 1 hit.
PROSITEiPS50109. HIS_KIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiO26544_METTH
AccessioniPrimary (citable) accession number: O26544
Entry historyi
Integrated into UniProtKB/TrEMBL: January 1, 1998
Last sequence update: January 1, 1998
Last modified: July 6, 2016
This is version 101 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.