O26399 (O26399_METTH) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
DNA-directed RNA polymerase RuleBase RU004279
EC=2.7.7.6 RuleBase RU004279

Gene names

Ordered Locus Names:

MTH_299 EMBL AAB84805.1

Organism

Methanobacterium thermoautotrophicum (strain Delta H)

Taxonomic identifier

187420 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Methanobacteria › Methanobacteriales › Methanobacteriaceae › Methanothermobacter

Protein attributes

Sequence length	664 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). RuleBase RU004279
Sequence similarities	Belongs to the RNA polymerase beta' chain family. RuleBase RU004279

Ontologies

Keywords
Biological process	Transcription
Cellular component	DNA-directed RNA polymerase RuleBase RU004279
Molecular function	Nucleotidyltransferase RuleBase RU004279 Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular function	DNA binding Inferred from electronic annotation. Source: InterPro DNA-directed RNA polymerase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	O26399 [UniParc]. Last modified January 1, 1998. Version 1. Checksum: A919357C008A1ABD	FASTA	664	75,160
	10 20 30 40 50 60 MRPSITLKNG ERSEDDLTHK LVDILRINQR LKENMEAGAP QLIVEDLWEL LQYHVTTYFD 70 80 90 100 110 120 NEASGVTPAR QRSGRQLLTL MQRLKSKKGM FSSELSKGRF RGNLSGKRVN FSARTVISPD 130 140 150 160 170 180 PNISINEVGV PEIIAREVTV PVYVTEWNID RMREYIENGP DVHPGANYVI RPDGRRIRIS 190 200 210 220 230 240 SKNTETVIEN LKPGYVVERH LKDGDIVLFN RQPSLHRMSL MAHRARVLPY KTFRLNLCVC 250 260 270 280 290 300 PPYNADFDGD EMNIHVLQTE ESRAEAKTLM LVQEHMISPR FGGPIIGSIN DQISGLYLLT 310 320 330 340 350 360 RKFAEFEEEE VFQLLRSAGI SLPSRRGTKW SGKEIFSLIL PDDLSMTYRA DVCRRCQECI 370 380 390 400 410 420 EDGCEYDAYV VIENGRLESG VIDKKTCGAF SGRLLGHIIR EYGTDEAREF LESASRLAIA 430 440 450 460 470 480 VLMRTGFTTS IMDFDVPEEA RQMIDSVLGM VMDRVEGLTE DKEDGRVEPV QVMSSEKNFE 490 500 510 520 530 540 ITIMKVLAGA RERGGEIARK YLGVDGNQGY MITRTGLKCS LLNFTQITAC LGQQSVRGER 550 560 570 580 590 600 ISRGYDNRTL PHFRKGELGA KSRGFVQSSY REGLDPIEFF FHAMGGRDAL VDTAVRTAQS 610 620 630 640 650 660 GYMQRRLINA LQDLTVDEDG RVRDSCGNVI QILYGEDGVS PWRGKNGEIV DLEQLVYEIR RKSP

References

[1]

"Complete genome sequence of Methanobacterium thermoautotrophicum deltaH: functional analysis and comparative genomics." Smith D.R., Doucette-Stamm L.A., Deloughery C., Lee H.-M., Dubois J., Aldredge T., Bashirzadeh R., Blakely D., Cook R., Gilbert K., Harrison D., Hoang L., Keagle P., Lumm W., Pothier B., Qiu D., Spadafora R., Vicare R. , Wang Y., Wierzbowski J., Gibson R., Jiwani N., Caruso A., Bush D., Safer H., Patwell D., Prabhakar S., McDougall S., Shimer G., Goyal A., Pietrovski S., Church G.M., Daniels C.J., Mao J.-I., Rice P., Noelling J., Reeve J.N. J. Bacteriol. 179:7135-7155(1997) [PubMed: 9371463] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Delta H.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE000666 Genomic DNA. Translation: AAB84805.1.
PIR	A69138.
RefSeq	NP_275442.1. NC_000916.1.
3D structure databases
HSSP	HSSP built from PDB template 1I6H based on UniProtKB P04050.
ProteinModelPortal	O26399.
SMR	O26399. Positions 13-660.
ModBase	Search...
Protein-protein interaction databases
STRING	O26399.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1470260.
GenomeReviews	Gene locus MTH_299 in contig AE000666_GR.
KEGG	mth:MTH299.
NMPDR	fig|187420.1.peg.297.
Phylogenomic databases
eggNOG	arNOG04559.
HOGENOM	HBG499785.
OMA	NGERSED.
Family and domain databases
InterPro	IPR000722. RNA_pol_asu. IPR006592. RNA_pol_N. IPR007080. RNA_pol_Rpb1_1. IPR007066. RNA_pol_Rpb1_3. IPR007083. RNA_pol_Rpb1_4. IPR007081. RNA_pol_Rpb1_5. [Graphical view]
KO	K03041.
Pfam	PF04997. RNA_pol_Rpb1_1. 1 hit. PF00623. RNA_pol_Rpb1_2. 1 hit. PF04983. RNA_pol_Rpb1_3. 1 hit. PF05000. RNA_pol_Rpb1_4. 1 hit. PF04998. RNA_pol_Rpb1_5. 1 hit. [Graphical view]
SMART	SM00663. RPOLA_N. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

O26399_METTH

Accession

Primary (citable) accession number: O26399

Entry history

Integrated into UniProtKB/TrEMBL:	January 1, 1998
Last sequence update:	January 1, 1998
Last modified:	November 16, 2011
This is version 69 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)