O26293 (Y191_METTH) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative glutamine amidotransferase MTH_191
EC=2.4.2.-

Gene names

Ordered Locus Names:

MTH_191

Organism

Methanobacterium thermoautotrophicum (strain Delta H)

Taxonomic identifier

187420 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Methanobacteria › Methanobacteriales › Methanobacteriaceae › Methanothermobacter

Protein attributes

Sequence length	305 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Contains 1 glutamine amidotransferase type-2 domain.

Ontologies

Keywords
Domain	Glutamine amidotransferase
Molecular function	Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	glutamine metabolic process Inferred from electronic annotation. Source: UniProtKB-KW purine base biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	amidophosphoribosyltransferase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Initiator methionine	1	1	Removed By similarity
	Chain	2 – 305	304	Putative glutamine amidotransferase MTH_191		PRO_0000056942
Regions
	Domain	2 – 305	304	Glutamine amidotransferase type-2
Sites
	Active site	2	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	O26293 [UniParc]. Last modified January 23, 2007. Version 3. Checksum: 56CD141A9D164A66	FASTA	305	33,910
	10 20 30 40 50 60 MCGIAGVVYK DGKLHSVGAD MTRMLHALQH RGPDSAGFAI YGGLGLEEND YLLNIEVKDK 70 80 90 100 110 120 PGLLDMVKET VELVSPIGSD EVIPSVENHI IYRCRITLES FSQLKPLIMD IDSIDDVIVL 130 140 150 160 170 180 NGSHSFEMIK DVGSVLEIAD RYDTWSKKGT HAIGHTRFST ESIVDRYHAH PFQSYIIPDI 190 200 210 220 230 240 TVVHNGQITN YWKIREPLER KGHIFETNND TECIVHYVAD KLASGYSLEE ALEQSVKDMD 250 260 270 280 290 300 GPFSYIVGTP QGVGIAKDQL GLRPGVMAEN DEVFAVASEE VSLREVMDTS EVEQISPGEV RVYEI

References

[1]

"Complete genome sequence of Methanobacterium thermoautotrophicum deltaH: functional analysis and comparative genomics." Smith D.R., Doucette-Stamm L.A., Deloughery C., Lee H.-M., Dubois J., Aldredge T., Bashirzadeh R., Blakely D., Cook R., Gilbert K., Harrison D., Hoang L., Keagle P., Lumm W., Pothier B., Qiu D., Spadafora R., Vicare R. , Wang Y., Wierzbowski J., Gibson R., Jiwani N., Caruso A., Bush D., Safer H., Patwell D., Prabhakar S., McDougall S., Shimer G., Goyal A., Pietrovski S., Church G.M., Daniels C.J., Mao J.-I., Rice P., Noelling J., Reeve J.N. J. Bacteriol. 179:7135-7155(1997) [PubMed: 9371463] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Delta H.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE000666 Genomic DNA. Translation: AAB84697.1.
PIR	A69122.
RefSeq	NP_275334.1. NC_000916.1.
3D structure databases
ProteinModelPortal	O26293.
ModBase	Search...
Protein-protein interaction databases
STRING	O26293.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1470152.
GenomeReviews	Gene locus MTH_191 in contig AE000666_GR.
KEGG	mth:MTH191.
NMPDR	fig|187420.1.peg.189.
Phylogenomic databases
eggNOG	arNOG04106.
HOGENOM	HBG299832.
OMA	GQITNYW.
ProtClustDB	CLSK878444.
Enzyme and pathway databases
BioCyc	MTHE187420:MTH191-MONOMER.
Family and domain databases
InterPro	IPR005854. Amd_phspho_trans. IPR000583. GATase_2. IPR017932. GATase_II. [Graphical view]
PANTHER	PTHR11907. Amd_phspho_trans. 1 hit.
Pfam	PF00310. GATase_2. 1 hit. [Graphical view]
PROSITE	PS51278. GATASE_TYPE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Y191_METTH

Accession

Primary (citable) accession number: O26293

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2000
Last sequence update:	January 23, 2007
Last modified:	October 19, 2011
This is version 64 of the entry and version 3 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program