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O26232

- PYRF_METTH

UniProt

O26232 - PYRF_METTH

Protein

Orotidine 5'-phosphate decarboxylase

Gene

pyrF

Organism
Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H) (Methanobacterium thermoautotrophicum)
Status
Reviewed - Annotation score: 4 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 114 (01 Oct 2014)
      Sequence version 1 (01 Jan 1998)
      Previous versions | rss
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    Functioni

    Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).

    Catalytic activityi

    Orotidine 5'-phosphate = UMP + CO2.

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei20 – 201Substrate
    Binding sitei42 – 421Substrate
    Active sitei72 – 721Proton donor
    Binding sitei127 – 1271Substrate
    Binding sitei202 – 2021Substrate; via amide nitrogen
    Binding sitei203 – 2031Substrate

    GO - Molecular functioni

    1. orotidine-5'-phosphate decarboxylase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. 'de novo' pyrimidine nucleobase biosynthetic process Source: InterPro
    2. 'de novo' UMP biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Decarboxylase, Lyase

    Keywords - Biological processi

    Pyrimidine biosynthesis

    Enzyme and pathway databases

    BioCyciMTHE187420:GJNM-129-MONOMER.
    UniPathwayiUPA00070; UER00120.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Orotidine 5'-phosphate decarboxylase (EC:4.1.1.23)
    Alternative name(s):
    OMP decarboxylase
    Short name:
    OMPDCase
    Short name:
    OMPdecase
    Gene namesi
    Name:pyrF
    Ordered Locus Names:MTH_129
    OrganismiMethanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H) (Methanobacterium thermoautotrophicum)
    Taxonomic identifieri187420 [NCBI]
    Taxonomic lineageiArchaeaEuryarchaeotaMethanobacteriaMethanobacterialesMethanobacteriaceaeMethanothermobacter
    ProteomesiUP000005223: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 228228Orotidine 5'-phosphate decarboxylasePRO_0000134612Add
    BLAST

    Interactioni

    Subunit structurei

    Homodimer.4 Publications

    Protein-protein interaction databases

    STRINGi187420.MTH129.

    Structurei

    Secondary structure

    1
    228
    Legend: HelixTurnBeta strand
    Show more details
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Beta strandi6 – 83
    Helixi12 – 143
    Beta strandi15 – 195
    Helixi24 – 3411
    Helixi35 – 373
    Beta strandi39 – 446
    Helixi45 – 517
    Helixi54 – 6310
    Beta strandi66 – 738
    Helixi77 – 8913
    Beta strandi93 – 997
    Helixi103 – 11614
    Beta strandi119 – 1235
    Helixi129 – 1324
    Helixi135 – 14915
    Beta strandi153 – 1553
    Beta strandi158 – 1603
    Helixi161 – 17111
    Beta strandi173 – 1797
    Helixi189 – 1924
    Turni193 – 1953
    Beta strandi197 – 2015
    Helixi203 – 2064
    Beta strandi208 – 2103
    Helixi211 – 22414

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    1DV7X-ray1.80A2-228[»]
    1DVJX-ray1.50A/B/C/D2-226[»]
    1KLYX-ray1.50A1-228[»]
    1KLZX-ray1.50A1-228[»]
    1KM0X-ray1.70A/B/C/D1-226[»]
    1KM1X-ray1.60A/B1-226[»]
    1KM2X-ray1.50A1-226[»]
    1KM3X-ray1.50A1-226[»]
    1KM4X-ray1.50A1-226[»]
    1KM5X-ray1.50A1-226[»]
    1KM6X-ray1.50A1-226[»]
    1LOLX-ray1.90A/B1-226[»]
    1LOQX-ray1.50A1-228[»]
    1LORX-ray1.60A1-228[»]
    1LOSX-ray1.90A/B/C/D1-228[»]
    1LP6X-ray1.90A/B1-226[»]
    1X1ZX-ray1.45A/B1-228[»]
    2E6YX-ray1.60A/B1-228[»]
    2ZZ1X-ray1.57A/B1-228[»]
    2ZZ2X-ray1.53A/B1-228[»]
    2ZZ3X-ray1.80A/B1-228[»]
    2ZZ4X-ray1.67A/B1-228[»]
    2ZZ5X-ray1.56A/B1-228[»]
    2ZZ6X-ray1.66A/B1-228[»]
    2ZZ7X-ray1.58A1-228[»]
    3G18X-ray1.60A/B1-228[»]
    3G1AX-ray1.50A/B1-228[»]
    3G1DX-ray1.50A/B1-228[»]
    3G1FX-ray2.50A/B/C/D/E/F/G/H/I/J/K/L/M1-228[»]
    3G1HX-ray2.30A/B/C/D/E/F/G/H/I/J/K/L/M1-228[»]
    3G1SX-ray1.40A/B1-228[»]
    3G1VX-ray1.30A/B1-228[»]
    3G1XX-ray1.55A/B1-228[»]
    3G1YX-ray1.40A/B1-228[»]
    3G22X-ray1.50A/B1-228[»]
    3G24X-ray1.50A/B1-228[»]
    3LHTX-ray1.35A/B1-228[»]
    3LHUX-ray1.60A/B1-228[»]
    3LHVX-ray1.35A/B/C/D1-228[»]
    3LHWX-ray1.35A/B1-228[»]
    3LHYX-ray1.40A/B1-228[»]
    3LHZX-ray1.40A/B1-228[»]
    3LI0X-ray1.50A/B1-228[»]
    3LI1X-ray1.35A/B1-228[»]
    3LLDX-ray1.45A/B1-228[»]
    3LLFX-ray1.30A/B1-228[»]
    3LTPX-ray1.40A/B1-228[»]
    3LTSX-ray1.43A/B1-228[»]
    3LTYX-ray1.50A/B1-228[»]
    3LV5X-ray1.44A/B1-228[»]
    3LV6X-ray1.45A/B1-228[»]
    3M1ZX-ray1.42A/B1-228[»]
    3M41X-ray1.40A/B1-228[»]
    3M43X-ray1.30A/B1-228[»]
    3M44X-ray1.40A/B1-228[»]
    3M47X-ray1.20A/B1-228[»]
    3M5XX-ray1.40A/B1-228[»]
    3M5YX-ray1.46A/B1-228[»]
    3M5ZX-ray1.35A/B1-228[»]
    3NQ6X-ray1.49A/B1-228[»]
    3NQ7X-ray1.44A/B1-228[»]
    3NQAX-ray1.40A/B1-228[»]
    3NQCX-ray1.53A/B1-228[»]
    3NQDX-ray1.42A/B1-228[»]
    3NQEX-ray1.42A/B1-228[»]
    3NQFX-ray1.31A/B1-228[»]
    3NQGX-ray1.42A/B1-228[»]
    3NQMX-ray1.32A/B1-228[»]
    3P5YX-ray1.60A/B1-228[»]
    3P5ZX-ray1.30A/B1-228[»]
    3P60X-ray1.40A/B1-228[»]
    3P61X-ray1.40A/B1-228[»]
    3PBUX-ray1.30A/B1-228[»]
    3PBVX-ray1.30A/B1-228[»]
    3PBWX-ray1.30A/B1-228[»]
    3PBYX-ray1.30A/B1-228[»]
    3PC0X-ray1.30A/B1-228[»]
    3QEZX-ray1.54A/B1-228[»]
    3QF0X-ray1.34A/B1-228[»]
    3QMRX-ray1.32A/B1-228[»]
    3QMSX-ray1.32A/B1-228[»]
    3QMTX-ray1.32A/B1-228[»]
    3RLUX-ray1.49A/B1-228[»]
    3RLVX-ray1.42A/B1-228[»]
    3SECX-ray1.70A1-226[»]
    3SGUX-ray1.70A1-226[»]
    3SIZX-ray1.32A/B1-228[»]
    3SJ3X-ray1.26A/B1-228[»]
    3SSJX-ray1.40A1-226[»]
    3SW6X-ray1.50A1-226[»]
    3SY5X-ray1.32A/B1-228[»]
    3THQX-ray1.50A/B1-226[»]
    3V1PX-ray1.37A/B1-228[»]
    3W07X-ray1.03A1-228[»]
    3WJWX-ray1.59A1-228[»]
    3WJXX-ray1.23A1-228[»]
    3WJYX-ray1.72A1-228[»]
    3WJZX-ray1.39A1-228[»]
    3WK0X-ray1.41A1-228[»]
    3WK1X-ray1.60A1-228[»]
    3WK2X-ray1.69A1-228[»]
    3WK3X-ray1.26A1-228[»]
    4FX6X-ray1.53M/N1-228[»]
    4FX8X-ray1.94A/B1-228[»]
    4FXRX-ray1.71A/B1-228[»]
    4GC4X-ray1.42A/B1-228[»]
    4LC6X-ray1.32A/B1-228[»]
    4LC8X-ray1.32A/B1-228[»]
    4NT0X-ray1.77A/B1-228[»]
    4NUWX-ray1.59A/B1-228[»]
    4NX5X-ray1.59A/B1-228[»]
    4O11X-ray1.59A/B1-228[»]
    4O8RX-ray2.29A/B/C/D/E/F/G/H/I/J/K/L/M1-228[»]
    ProteinModelPortaliO26232.
    SMRiO26232. Positions 9-228.
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiO26232.

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni70 – 7910Substrate binding
    Regioni180 – 19011Substrate bindingAdd
    BLAST

    Sequence similaritiesi

    Phylogenomic databases

    eggNOGiCOG0284.
    KOiK01591.
    OMAiTEMSHPG.

    Family and domain databases

    Gene3Di3.20.20.70. 1 hit.
    HAMAPiMF_01200_A. OMPdecase_type1_A.
    InterProiIPR013785. Aldolase_TIM.
    IPR014732. OMPdecase.
    IPR018089. OMPdecase_AS.
    IPR001754. OMPdeCOase_dom.
    IPR011060. RibuloseP-bd_barrel.
    [Graphical view]
    PfamiPF00215. OMPdecase. 1 hit.
    [Graphical view]
    SMARTiSM00934. OMPdecase. 1 hit.
    [Graphical view]
    SUPFAMiSSF51366. SSF51366. 1 hit.
    TIGRFAMsiTIGR01740. pyrF. 1 hit.
    PROSITEiPS00156. OMPDECASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    O26232-1 [UniParc]FASTAAdd to Basket

    « Hide

    MRSRRVDVMD VMNRLILAMD LMNRDDALRV TGEVREYIDT VKIGYPLVLS    50
    EGMDIIAEFR KRFGCRIIAD FKVADIPETN EKICRATFKA GADAIIVHGF 100
    RGADSVRACL NVAEEMGREV FLLTEMSHPG AEMFIQGAAD EIARMGVDLG 150
    VKNYVGPSTR PERLSRLREI IGQDSFLISP GVGAQGGDPG ETLRFADAII 200
    VGRSIYLADN PAAAAAGIIE SIKDLLNP 228
    Length:228
    Mass (Da):24,915
    Last modified:January 1, 1998 - v1
    Checksum:iA7B65D94C8663D78
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE000666 Genomic DNA. Translation: AAB84635.1.
    PIRiF69038.
    RefSeqiNP_275272.1. NC_000916.1.
    WP_010875768.1. NC_000916.1.

    Genome annotation databases

    EnsemblBacteriaiAAB84635; AAB84635; MTH_129.
    GeneIDi1470090.
    KEGGimth:MTH129.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE000666 Genomic DNA. Translation: AAB84635.1 .
    PIRi F69038.
    RefSeqi NP_275272.1. NC_000916.1.
    WP_010875768.1. NC_000916.1.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    1DV7 X-ray 1.80 A 2-228 [» ]
    1DVJ X-ray 1.50 A/B/C/D 2-226 [» ]
    1KLY X-ray 1.50 A 1-228 [» ]
    1KLZ X-ray 1.50 A 1-228 [» ]
    1KM0 X-ray 1.70 A/B/C/D 1-226 [» ]
    1KM1 X-ray 1.60 A/B 1-226 [» ]
    1KM2 X-ray 1.50 A 1-226 [» ]
    1KM3 X-ray 1.50 A 1-226 [» ]
    1KM4 X-ray 1.50 A 1-226 [» ]
    1KM5 X-ray 1.50 A 1-226 [» ]
    1KM6 X-ray 1.50 A 1-226 [» ]
    1LOL X-ray 1.90 A/B 1-226 [» ]
    1LOQ X-ray 1.50 A 1-228 [» ]
    1LOR X-ray 1.60 A 1-228 [» ]
    1LOS X-ray 1.90 A/B/C/D 1-228 [» ]
    1LP6 X-ray 1.90 A/B 1-226 [» ]
    1X1Z X-ray 1.45 A/B 1-228 [» ]
    2E6Y X-ray 1.60 A/B 1-228 [» ]
    2ZZ1 X-ray 1.57 A/B 1-228 [» ]
    2ZZ2 X-ray 1.53 A/B 1-228 [» ]
    2ZZ3 X-ray 1.80 A/B 1-228 [» ]
    2ZZ4 X-ray 1.67 A/B 1-228 [» ]
    2ZZ5 X-ray 1.56 A/B 1-228 [» ]
    2ZZ6 X-ray 1.66 A/B 1-228 [» ]
    2ZZ7 X-ray 1.58 A 1-228 [» ]
    3G18 X-ray 1.60 A/B 1-228 [» ]
    3G1A X-ray 1.50 A/B 1-228 [» ]
    3G1D X-ray 1.50 A/B 1-228 [» ]
    3G1F X-ray 2.50 A/B/C/D/E/F/G/H/I/J/K/L/M 1-228 [» ]
    3G1H X-ray 2.30 A/B/C/D/E/F/G/H/I/J/K/L/M 1-228 [» ]
    3G1S X-ray 1.40 A/B 1-228 [» ]
    3G1V X-ray 1.30 A/B 1-228 [» ]
    3G1X X-ray 1.55 A/B 1-228 [» ]
    3G1Y X-ray 1.40 A/B 1-228 [» ]
    3G22 X-ray 1.50 A/B 1-228 [» ]
    3G24 X-ray 1.50 A/B 1-228 [» ]
    3LHT X-ray 1.35 A/B 1-228 [» ]
    3LHU X-ray 1.60 A/B 1-228 [» ]
    3LHV X-ray 1.35 A/B/C/D 1-228 [» ]
    3LHW X-ray 1.35 A/B 1-228 [» ]
    3LHY X-ray 1.40 A/B 1-228 [» ]
    3LHZ X-ray 1.40 A/B 1-228 [» ]
    3LI0 X-ray 1.50 A/B 1-228 [» ]
    3LI1 X-ray 1.35 A/B 1-228 [» ]
    3LLD X-ray 1.45 A/B 1-228 [» ]
    3LLF X-ray 1.30 A/B 1-228 [» ]
    3LTP X-ray 1.40 A/B 1-228 [» ]
    3LTS X-ray 1.43 A/B 1-228 [» ]
    3LTY X-ray 1.50 A/B 1-228 [» ]
    3LV5 X-ray 1.44 A/B 1-228 [» ]
    3LV6 X-ray 1.45 A/B 1-228 [» ]
    3M1Z X-ray 1.42 A/B 1-228 [» ]
    3M41 X-ray 1.40 A/B 1-228 [» ]
    3M43 X-ray 1.30 A/B 1-228 [» ]
    3M44 X-ray 1.40 A/B 1-228 [» ]
    3M47 X-ray 1.20 A/B 1-228 [» ]
    3M5X X-ray 1.40 A/B 1-228 [» ]
    3M5Y X-ray 1.46 A/B 1-228 [» ]
    3M5Z X-ray 1.35 A/B 1-228 [» ]
    3NQ6 X-ray 1.49 A/B 1-228 [» ]
    3NQ7 X-ray 1.44 A/B 1-228 [» ]
    3NQA X-ray 1.40 A/B 1-228 [» ]
    3NQC X-ray 1.53 A/B 1-228 [» ]
    3NQD X-ray 1.42 A/B 1-228 [» ]
    3NQE X-ray 1.42 A/B 1-228 [» ]
    3NQF X-ray 1.31 A/B 1-228 [» ]
    3NQG X-ray 1.42 A/B 1-228 [» ]
    3NQM X-ray 1.32 A/B 1-228 [» ]
    3P5Y X-ray 1.60 A/B 1-228 [» ]
    3P5Z X-ray 1.30 A/B 1-228 [» ]
    3P60 X-ray 1.40 A/B 1-228 [» ]
    3P61 X-ray 1.40 A/B 1-228 [» ]
    3PBU X-ray 1.30 A/B 1-228 [» ]
    3PBV X-ray 1.30 A/B 1-228 [» ]
    3PBW X-ray 1.30 A/B 1-228 [» ]
    3PBY X-ray 1.30 A/B 1-228 [» ]
    3PC0 X-ray 1.30 A/B 1-228 [» ]
    3QEZ X-ray 1.54 A/B 1-228 [» ]
    3QF0 X-ray 1.34 A/B 1-228 [» ]
    3QMR X-ray 1.32 A/B 1-228 [» ]
    3QMS X-ray 1.32 A/B 1-228 [» ]
    3QMT X-ray 1.32 A/B 1-228 [» ]
    3RLU X-ray 1.49 A/B 1-228 [» ]
    3RLV X-ray 1.42 A/B 1-228 [» ]
    3SEC X-ray 1.70 A 1-226 [» ]
    3SGU X-ray 1.70 A 1-226 [» ]
    3SIZ X-ray 1.32 A/B 1-228 [» ]
    3SJ3 X-ray 1.26 A/B 1-228 [» ]
    3SSJ X-ray 1.40 A 1-226 [» ]
    3SW6 X-ray 1.50 A 1-226 [» ]
    3SY5 X-ray 1.32 A/B 1-228 [» ]
    3THQ X-ray 1.50 A/B 1-226 [» ]
    3V1P X-ray 1.37 A/B 1-228 [» ]
    3W07 X-ray 1.03 A 1-228 [» ]
    3WJW X-ray 1.59 A 1-228 [» ]
    3WJX X-ray 1.23 A 1-228 [» ]
    3WJY X-ray 1.72 A 1-228 [» ]
    3WJZ X-ray 1.39 A 1-228 [» ]
    3WK0 X-ray 1.41 A 1-228 [» ]
    3WK1 X-ray 1.60 A 1-228 [» ]
    3WK2 X-ray 1.69 A 1-228 [» ]
    3WK3 X-ray 1.26 A 1-228 [» ]
    4FX6 X-ray 1.53 M/N 1-228 [» ]
    4FX8 X-ray 1.94 A/B 1-228 [» ]
    4FXR X-ray 1.71 A/B 1-228 [» ]
    4GC4 X-ray 1.42 A/B 1-228 [» ]
    4LC6 X-ray 1.32 A/B 1-228 [» ]
    4LC8 X-ray 1.32 A/B 1-228 [» ]
    4NT0 X-ray 1.77 A/B 1-228 [» ]
    4NUW X-ray 1.59 A/B 1-228 [» ]
    4NX5 X-ray 1.59 A/B 1-228 [» ]
    4O11 X-ray 1.59 A/B 1-228 [» ]
    4O8R X-ray 2.29 A/B/C/D/E/F/G/H/I/J/K/L/M 1-228 [» ]
    ProteinModelPortali O26232.
    SMRi O26232. Positions 9-228.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 187420.MTH129.

    Chemistry

    BindingDBi O26232.
    ChEMBLi CHEMBL5688.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAB84635 ; AAB84635 ; MTH_129 .
    GeneIDi 1470090.
    KEGGi mth:MTH129.

    Phylogenomic databases

    eggNOGi COG0284.
    KOi K01591.
    OMAi TEMSHPG.

    Enzyme and pathway databases

    UniPathwayi UPA00070 ; UER00120 .
    BioCyci MTHE187420:GJNM-129-MONOMER.

    Miscellaneous databases

    EvolutionaryTracei O26232.
    PROi O26232.

    Family and domain databases

    Gene3Di 3.20.20.70. 1 hit.
    HAMAPi MF_01200_A. OMPdecase_type1_A.
    InterProi IPR013785. Aldolase_TIM.
    IPR014732. OMPdecase.
    IPR018089. OMPdecase_AS.
    IPR001754. OMPdeCOase_dom.
    IPR011060. RibuloseP-bd_barrel.
    [Graphical view ]
    Pfami PF00215. OMPdecase. 1 hit.
    [Graphical view ]
    SMARTi SM00934. OMPdecase. 1 hit.
    [Graphical view ]
    SUPFAMi SSF51366. SSF51366. 1 hit.
    TIGRFAMsi TIGR01740. pyrF. 1 hit.
    PROSITEi PS00156. OMPDECASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H.
    2. "Purification, crystallization and preliminary X-ray study of orotidine 5'-monophosphate decarboxylase."
      Wu N., Christendat D., Dharamsi A., Pai E.F.
      Acta Crystallogr. D 56:912-914(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: CRYSTALLIZATION.
      Strain: ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H.
    3. "Electrostatic stress in catalysis: structure and mechanism of the enzyme orotidine monophosphate decarboxylase."
      Wu N., Mo Y., Gao J., Pai E.F.
      Proc. Natl. Acad. Sci. U.S.A. 97:2017-2022(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (1.5 ANGSTROMS) OF NATIVE PROTEIN AND COMPLEX WITH 6-AZAUMP, SUBUNIT.
      Strain: ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H.
    4. "Mapping the active site-ligand interactions of orotidine 5'-monophosphate decarboxylase by crystallography."
      Wu N., Gillon W., Pai E.F.
      Biochemistry 41:4002-4011(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (1.5 ANGSTROMS) OF MUTANTS ALA-42; GLY-70; ALA-70; ALA-72; ALA-70/ALA-72; ASN-75; ALA-127 AND ALA-185 IN COMPLEX WITH DIFFERENT LIGANDS, SUBUNIT.
      Strain: ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H.
    5. "Crystal structures of inhibitor complexes reveal an alternate binding mode in orotidine-5'-monophosphate decarboxylase."
      Wu N., Pai E.F.
      J. Biol. Chem. 277:28080-28087(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (1.5 ANGSTROMS) OF COMPLEXES WITH BMP; CMP; UMP; XMP AND OF MUTANT DELTA ALA-203 IN COMPLEX WITH 6-AZAUMP, SUBUNIT.
      Strain: ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H.
    6. Cited for: X-RAY CRYSTALLOGRAPHY (1.45 ANGSTROMS) OF COMPLEX WITH BMP, SUBUNIT.
      Strain: ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H.

    Entry informationi

    Entry nameiPYRF_METTH
    AccessioniPrimary (citable) accession number: O26232
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 30, 2000
    Last sequence update: January 1, 1998
    Last modified: October 1, 2014
    This is version 114 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    3D-structure, Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3