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Reviewed, UniProtKB/Swiss-Prot O26119 (RNP1_METTH)

Last modified January 19, 2010. Version 65. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Ribonuclease P protein component 1
      Short name=RNase P component 1
    EC=3.1.26.5
Gene names
Name: rnp1
Ordered Locus Names: MTH_11
OrganismMethanobacterium thermoautotrophicum [Complete proteome] [HAMAP]
Taxonomic identifier187420 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaMethanobacteriaMethanobacterialesMethanobacteriaceaeMethanothermobacter

Protein attributes

Sequence length93 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level.

General annotation (Comments)

Function

Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends By similarity. HAMAP MF_00754

Catalytic activity

Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor. HAMAP MF_00754

Subunit structure

Consists of a catalytic RNA component and at least 4 protein subunits. HAMAP MF_00754

Sequence similarities

Belongs to the eukaryotic/archaeal RNase P protein component 1 family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 9393Ribonuclease P protein component 1 HAMAP MF_00754
PRO_0000128433

Secondary structure

................... 93
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
O26119-1 [UniParc].

Last modified January 1, 1998. Version 1.
Checksum: 9641D6240AAE7928

FASTA9310,740
        10         20         30         40         50         60 
MITPRNIFRH ELIGLSVRIA RSVHRDIQGI SGRVVDETRN TLRIEMDDGR EITVPKGIAV 

        70         80         90 
FHFRTPQGEL VEIDGRALVA RPEERIKKKF RKP 

« Hide

References

« Hide 'large scale' references
[1]"Complete genome sequence of Methanobacterium thermoautotrophicum deltaH: functional analysis and comparative genomics."
Smith D.R., Doucette-Stamm L.A., Deloughery C., Lee H.-M., Dubois J., Aldredge T., Bashirzadeh R., Blakely D., Cook R., Gilbert K., Harrison D., Hoang L., Keagle P., Lumm W., Pothier B., Qiu D., Spadafora R., Vicare R. expand/collapse author list , Wang Y., Wierzbowski J., Gibson R., Jiwani N., Caruso A., Bush D., Safer H., Patwell D., Prabhakar S., McDougall S., Shimer G., Goyal A., Pietrovski S., Church G.M., Daniels C.J., Mao J.-I., Rice P., Noelling J., Reeve J.N.
J. Bacteriol. 179:7135-7155(1997) [PubMed: 9371463] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Delta H.
[2]"Archaeal RNase P has multiple protein subunits homologous to eukaryotic nuclear RNase P proteins."
Hall T.A., Brown J.W.
RNA 8:296-306(2002) [PubMed: 12003490] [Abstract]
Cited for: CHARACTERIZATION.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE000666 Genomic DNA. Translation: AAB84512.1.
PIRB69013.
RefSeqNP_275156.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
1OQKNMR-A2-93[»]
ModBaseSearch...

Protein-protein interaction databases

STRINGO26119.

Genome annotation databases

GeneID1469973.
GenomeReviewsGene locus MTH_11 in contig AE000666_GR.
KEGGmth:MTH11.
NMPDRfig|187420.1.peg.11.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGarNOG12604.
HOGENOMHBG704950.
OMAVINETRN.

Enzyme and pathway databases

BioCycMTHE187420:MTH11-MONOMER.
BRENDA3.1.26.5. 270.

Family and domain databases

HAMAPMF_00754. RNase_P_1.
[Tree]
InterProIPR002730. RNase_P/MRP_p29_euk/arc.
[Graphical view]
Gene3DG3DSA:2.30.30.210. RNase_P_Rpp29. 1 hit.
PfamPF01868. UPF0086. 1 hit.
[Graphical view]
SMARTSM00538. POP4. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameRNP1_METTH
AccessionPrimary (citable) accession number: O26119
Entry history
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: January 1, 1998
Last modified: January 19, 2010
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents