Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Methionine import ATP-binding protein MetN

Gene

metN

Organism
Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi36 – 43ATPUniRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase
Biological processAmino-acid transport, Transport
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciHPY:HP1576-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Methionine import ATP-binding protein MetNUniRule annotation (EC:3.6.3.-UniRule annotation)
Gene namesi
Name:metNUniRule annotation
Ordered Locus Names:HP_1576
OrganismiHelicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Taxonomic identifieri85962 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeHelicobacter
Proteomesi
  • UP000000429 Componenti: Chromosome

Subcellular locationi

  • Cell inner membrane UniRule annotation; Peripheral membrane protein UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002703101 – 327Methionine import ATP-binding protein MetNAdd BLAST327

Proteomic databases

PaxDbiO26096
PRIDEiO26096

Interactioni

Subunit structurei

The complex is composed of two ATP-binding proteins (MetN), two transmembrane proteins (MetI) and a solute-binding protein (MetQ).UniRule annotation

Protein-protein interaction databases

DIPiDIP-3488N
IntActiO26096, 3 interactors
MINTiO26096
STRINGi85962.HP1576

Structurei

3D structure databases

ProteinModelPortaliO26096
SMRiO26096
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini3 – 239ABC transporterUniRule annotationAdd BLAST237

Sequence similaritiesi

Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family. [View classification]UniRule annotation

Phylogenomic databases

eggNOGiENOG4108JEI Bacteria
COG1135 LUCA
KOiK02071
OMAiLIRLINC

Family and domain databases

InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR026253 ABC_MetN
IPR003439 ABC_transporter-like
IPR017871 ABC_transporter_CS
IPR017908 ABC_transprt_methionine_MetN_C
IPR018449 NIL_domain
IPR027417 P-loop_NTPase
PANTHERiPTHR43166:SF18 PTHR43166:SF18, 1 hit
PfamiView protein in Pfam
PF00005 ABC_tran, 1 hit
PF09383 NIL, 1 hit
SMARTiView protein in SMART
SM00382 AAA, 1 hit
SM00930 NIL, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS00211 ABC_TRANSPORTER_1, 1 hit
PS50893 ABC_TRANSPORTER_2, 1 hit
PS51264 METN, 1 hit

Sequencei

Sequence statusi: Complete.

O26096-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVVELKNIEK IYENGFHALK GVNLELKKGD ILGVIGYSGA GKSTLIRLIN
60 70 80 90 100
CLERPSSGEV LVNGVNLLKL KPKELQKARQ KIGMIFQHFN LLSAKNVFEN
110 120 130 140 150
VAFALEIARW EKNKIKSRVH ELLELVGLED KMHFYPKQLS GGQKQRVAIA
160 170 180 190 200
RSLANCPDLL LCDEATSALD SKTTHSILTL LSGIQKKLDL SIVFITHEIE
210 220 230 240 250
VVKELCNQMC VISSGEIVER GSVEEIFANP KHAVTKELLG IRNEHADKKS
260 270 280 290 300
QDVYRIVFLG EHLDEPIISN LIKRFKIDVS IISGNIEELT TKDIGYLVVR
310 320
FLGNTAETQR ALEYLNALGL QVEKLKD
Length:327
Mass (Da):36,622
Last modified:January 1, 1998 - v1
Checksum:i89F50E5A8D7D1E7B
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti96N → D in AAC45666 (PubMed:9294450).Curated1
Sequence conflicti113N → T in AAC45666 (PubMed:9294450).Curated1
Sequence conflicti132M → V in AAC45666 (PubMed:9294450).Curated1
Sequence conflicti145Q → E in AAC45666 (PubMed:9294450).Curated1
Sequence conflicti192I → V in AAC45666 (PubMed:9294450).Curated1
Sequence conflicti198E → Q in AAC45666 (PubMed:9294450).Curated1
Sequence conflicti247D → N in AAC45666 (PubMed:9294450).Curated1
Sequence conflicti279V → M in AAC45666 (PubMed:9294450).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF010307 Genomic DNA Translation: AAC45666.1
AE000511 Genomic DNA Translation: AAD08616.1
PIRiH64716
RefSeqiNP_208367.1, NC_000915.1
WP_000259757.1, NC_018939.1

Genome annotation databases

EnsemblBacteriaiAAD08616; AAD08616; HP_1576
GeneIDi899715
KEGGiheo:C694_08165
hpy:HP1576
PATRICifig|85962.47.peg.1694

Similar proteinsi

Entry informationi

Entry nameiMETN_HELPY
AccessioniPrimary (citable) accession number: O26096
Secondary accession number(s): O30552
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 9, 2007
Last sequence update: January 1, 1998
Last modified: May 23, 2018
This is version 125 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health