O26091 (RLPA_HELPY) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
RlpA-like lipoprotein

Gene names

Ordered Locus Names:

HP_1571

Organism

Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)

Taxonomic identifier

85962 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Epsilonproteobacteria › Campylobacterales › Helicobacteraceae › Helicobacter

Protein attributes

Sequence length	315 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology

General annotation (Comments)

Subcellular location	Cell membrane; Lipid-anchor Probable.
Sequence similarities	Belongs to the rlpA family.

Ontologies

Keywords
Cellular component	Cell membrane Membrane
Domain	Signal
PTM	Lipoprotein Palmitate
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular component	plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 19	19	Potential
	Chain	20 – 315	296	RlpA-like lipoprotein		PRO_0000030804
Amino acid modifications
	Lipidation	20	1	N-palmitoyl cysteine Potential
	Lipidation	20	1	S-diacylglycerol cysteine Potential

Sequences

	Sequence		Length	Mass (Da)
	O26091 [UniParc]. Last modified January 1, 1998. Version 1. Checksum: 194402D94C1FC14D	FASTA	315	35,476
	10 20 30 40 50 60 MGLALEKVCF LGVIFLISAC TVKKEGVKNL SYKHESLRAY ENAKDYDPTT KKAAYKRNFF 70 80 90 100 110 120 ERHFKRYSDS QDSNTKDQPL DNGMRDSSSI QRATMRPYQV GGKWYYPTKV DLGEKFDGVA 130 140 150 160 170 180 SWYGPNFHAK KTSNGEIYNM YAHTAAHKTL PMNTVVKVIN VDNNLSTIVR INDRGPFVSD 190 200 210 220 230 240 RIIDLSNAAA RDIDMVKKGT ASVRLIVLGF GGVISTQYEQ SFNASSSKIL HKEFKVGESE 250 260 270 280 290 300 KSVSGGKFSL QMGAFRNQIG AQTLADKLQA ENPNYSVKVA FKDDLYKVLV QGFQSEEEAR 310 DFMKKYNQNA VLTRE

References

[1]

"The complete genome sequence of the gastric pathogen Helicobacter pylori." Tomb J.-F., White O., Kerlavage A.R., Clayton R.A., Sutton G.G., Fleischmann R.D., Ketchum K.A., Klenk H.-P., Gill S.R., Dougherty B.A., Nelson K.E., Quackenbush J., Zhou L., Kirkness E.F., Peterson S.N., Loftus B.J., Richardson D.L., Dodson R.J. , Khalak H.G., Glodek A., McKenney K., FitzGerald L.M., Lee N., Adams M.D., Hickey E.K., Berg D.E., Gocayne J.D., Utterback T.R., Peterson J.D., Kelley J.M., Cotton M.D., Weidman J.F., Fujii C., Bowman C., Watthey L., Wallin E., Hayes W.S., Borodovsky M., Karp P.D., Smith H.O., Fraser C.M., Venter J.C. Nature 388:539-547(1997) [PubMed: 9252185] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 700392 / 26695.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE000511 Genomic DNA. Translation: AAD08608.1.
PIR	C64716.
RefSeq	NP_208362.1. NC_000915.1.
3D structure databases
ProteinModelPortal	O26091.
ModBase	Search...
Protein-protein interaction databases
DIP	DIP-3473N.
MINT	MINT-159865.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	899720.
GenomeReviews	Gene locus HP_1571 in contig AE000511_GR.
KEGG	hpy:HP1571.
PATRIC	20594569. VBIHelPyl33062_1652.
TIGR	HP_1571.
Phylogenomic databases
eggNOG	COG0797.
KO	K03642.
OMA	YENAKDY.
ProtClustDB	CLSK496576.
Family and domain databases
Gene3D	G3DSA:3.30.70.1070. Spore_cell-division_bac. 1 hit.
InterPro	IPR009009. Barwin-related_endoglucanase. IPR012997. RplA_bac. IPR007730. Sporulation-related_dom. [Graphical view]
Pfam	PF03330. DPBB_1. 1 hit. PF05036. SPOR. 1 hit. [Graphical view]
SUPFAM	SSF50685. Barwin_like. 1 hit. SSF110997. Spore_cell-division_bac. 1 hit.
TIGRFAMs	TIGR00413. RlpA. 1 hit.
PROSITE	PS51257. PROKAR_LIPOPROTEIN. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RLPA_HELPY

Accession

Primary (citable) accession number: O26091

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 5, 2002
Last sequence update:	January 1, 1998
Last modified:	May 16, 2012
This is version 79 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program