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O26073 (SECF_HELPY) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 86. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Protein translocase subunit SecF
Gene names
Name:secF
Ordered Locus Names:HP_1549
OrganismHelicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori) [Reference proteome] [HAMAP]
Taxonomic identifier85962 [NCBI]
Taxonomic lineageBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeHelicobacter

Protein attributes

Sequence length323 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA By similarity. HAMAP-Rule MF_01464

Subunit structure

Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC By similarity.

Subcellular location

Cell inner membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_01464.

Sequence similarities

Belongs to the SecD/SecF family. SecF subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 323323Protein translocase subunit SecF HAMAP-Rule MF_01464
PRO_0000095980

Regions

Transmembrane19 – 3921Helical; Potential
Transmembrane138 – 15821Helical; Potential
Transmembrane162 – 18221Helical; Potential
Transmembrane189 – 20921Helical; Potential
Transmembrane244 – 26421Helical; Potential
Transmembrane269 – 28921Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
O26073 [UniParc].

Last modified January 1, 1998. Version 1.
Checksum: EAD9190473F21F59

FASTA32336,277
        10         20         30         40         50         60 
MELFKRTRIL SFMRYSNYGV IVSAILALLA LGLLFFKGFS LGIDFAGGSL VQVRYTQNAP 

        70         80         90        100        110        120 
IKEVRDLFEK EARFKGVQVS EFGSKEEILI KFPFVETAEN EDLNAIVANI LKPSGDFEIR 

       130        140        150        160        170        180 
KFDTVGPRVG SELKEKGILS LILALIAIMV YVSFRYEWRF ALASVIALVH DVILVASSVI 

       190        200        210        220        230        240 
VFKIDMNLEV IAALLTLIGY SINDTIIIFD RIREEMLSQK TKNATQAIDE AISSTLTRTL 

       250        260        270        280        290        300 
LTSLTVFFVV LILCVFGSKI IIGFSLPMLI GTIVGTYSSI FIAPKVALLL GFDMDKYYEN 

       310        320 
ETRKIKKAQE KEKMRRLYES GQV 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE000511 Genomic DNA. Translation: AAD08587.1.
PIRE64713.
RefSeqNP_208340.1. NC_000915.1.
YP_006935475.1. NC_018939.1.

3D structure databases

ProteinModelPortalO26073.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING85962.HP1549.

Proteomic databases

PRIDEO26073.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAD08587; AAD08587; HP_1549.
GeneID899742.
KEGGheo:C694_08025.
hpy:HP1549.
PATRIC20594521. VBIHelPyl33062_1628.

Phylogenomic databases

eggNOGCOG0341.
KOK03074.
OMALSSKFFE.
OrthoDBEOG676Z5R.

Enzyme and pathway databases

BioCycHPY:HP1549-MONOMER.

Family and domain databases

HAMAPMF_01464_B. SecF_B.
InterProIPR022813. SecD/SecF_arch_bac.
IPR022645. SecD/SecF_bac.
IPR022646. SecD/SecF_CS.
IPR005665. SecF_bac.
[Graphical view]
PfamPF07549. Sec_GG. 1 hit.
PF02355. SecD_SecF. 1 hit.
[Graphical view]
PRINTSPR01755. SECFTRNLCASE.
TIGRFAMsTIGR00916. 2A0604s01. 1 hit.
TIGR00966. 3a0501s07. 1 hit.
ProtoNetSearch...

Entry information

Entry nameSECF_HELPY
AccessionPrimary (citable) accession number: O26073
Entry history
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: January 1, 1998
Last modified: July 9, 2014
This is version 86 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Helicobacter pylori

Helicobacter pylori (strain 26695): entries and gene names