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Protein
Submitted name:

Cation-transporting ATPase, P-type (CopA)

Gene

HP_1503

Organism
Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

HydrolaseUniRule annotation

Enzyme and pathway databases

BioCyciHPY:HP1503-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Cation-transporting ATPase, P-type (CopA)Imported
Gene namesi
Ordered Locus Names:HP_1503Imported
OrganismiHelicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)Imported
Taxonomic identifieri85962 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeHelicobacter
Proteomesi
  • UP000000429 Componenti: Chromosome

Subcellular locationi

  • Cell membrane UniRule annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei165 – 185HelicalUniRule annotationAdd BLAST21
Transmembranei214 – 232HelicalUniRule annotationAdd BLAST19
Transmembranei244 – 266HelicalUniRule annotationAdd BLAST23
Transmembranei425 – 446HelicalUniRule annotationAdd BLAST22
Transmembranei452 – 481HelicalUniRule annotationAdd BLAST30
Transmembranei735 – 759HelicalUniRule annotationAdd BLAST25
Transmembranei765 – 783HelicalUniRule annotationAdd BLAST19

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiO26033.
PRIDEiO26033.

Interactioni

Protein-protein interaction databases

DIPiDIP-3099N.
IntActiO26033. 8 interactors.
MINTiMINT-178933.
STRINGi85962.HP1503.

Structurei

3D structure databases

ProteinModelPortaliO26033.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini83 – 148HMAInterPro annotationAdd BLAST66

Sequence similaritiesi

Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily. [View classification]UniRule annotation
Contains 1 HMA domain.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

eggNOGiENOG4105C59. Bacteria.
COG2217. LUCA.
KOiK17686.
OMAiCLALESH.

Family and domain databases

CDDicd00371. HMA. 1 hit.
Gene3Di2.70.150.10. 1 hit.
3.40.50.1000. 2 hits.
InterProiIPR021993. ATPase-cat-bd.
IPR018303. ATPase_P-typ_P_site.
IPR008250. ATPase_P-typ_transduc_dom_A.
IPR023214. HAD-like_dom.
IPR006121. HMA_dom.
IPR027256. P-typ_ATPase_IB.
IPR001757. P_typ_ATPase.
[Graphical view]
PfamiPF12156. ATPase-cat_bd. 1 hit.
PF00122. E1-E2_ATPase. 1 hit.
PF00403. HMA. 1 hit.
[Graphical view]
SUPFAMiSSF55008. SSF55008. 1 hit.
SSF56784. SSF56784. 2 hits.
TIGRFAMsiTIGR01525. ATPase-IB_hvy. 1 hit.
TIGR01494. ATPase_P-type. 1 hit.
PROSITEiPS00154. ATPASE_E1_E2. 1 hit.
PS50846. HMA_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O26033-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKCSHCQLEF KESELFKEVI NHKELHFCCT GCARVYALLL DLNLESFYDK
60 70 80 90 100
LNDSTLAPVT PQDSMSALEL EQALEENNKG DFILNLLLEK THCNACLWLN
110 120 130 140 150
QKVLERLSGV KKVSVNFTTH HLQIVFEKSL NPKEIIQKIE SLGYGAKIYN
160 170 180 190 200
AQNYTLKAQK EQRSYLLTLS VGFFATMNLM FIAIAKYASY GGASYGGANY
210 220 230 240 250
GAGMDKLMQR NLDLVSLFLS LLVLVVVGRF FIKGAFYGLK NGVLGMDLSV
260 270 280 290 300
SFGALSAFVY SVYAMLVSQE TYFEASSTIL TLVFGSKFLE LKARLFANEK
310 320 330 340 350
CLALESHEIH SVIVVENGKQ TEKHPKDVAI GSVVWVPSGA KIALDGVLLN
360 370 380 390 400
NASVDASLIS GEFKPLELGV NDPILGGYVN VGVPFSYQVS ANFQNSRLSG
410 420 430 440 450
LLETLKKSFL EKPLIESSAN QIADIFSKAV LFLAFVSFLL WQFGLGGNFE
460 470 480 490 500
KALMVCISVL VISCPCAFAL ATPIALVIGV FKNPLIVFKE ALFLETLAKV
510 520 530 540 550
KKIFIDKTGT LTQKEVLLKE KIIYEEFDGR LLKSLLKVRE HLAHSAILKS
560 570 580 590 600
LDGDEVSLEK IEFFAHGLKA SYQNETLLVG SLKFLGSMGV DIPMKESANI
610 620 630 640 650
MVGFAKNETL CALFILEERL KANAKEVVQA LQNKGLELEI LSGDNESSVK
660 670 680 690 700
ECAKKLGISN YHAHLTPEDK AQTISSYKGV CAMVGDGNND ALALKQASVS
710 720 730 740 750
LGFEKSALSK SACDILLLEE DLSLLKKAFD NAQKVYQVVL QNIVLSLIYN
760 770 780
AILIPVAMLG YINPLIASLS MSASSLLVVL NSLRLKRS
Length:788
Mass (Da):86,535
Last modified:January 1, 1998 - v1
Checksum:i4A26106CF6CDBB85
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000511 Genomic DNA. Translation: AAD08539.1.
PIRiG64707.
RefSeqiNP_208294.1. NC_000915.1.
WP_000650233.1. NC_018939.1.

Genome annotation databases

EnsemblBacteriaiAAD08539; AAD08539; HP_1503.
GeneIDi899788.
KEGGiheo:C694_07785.
hpy:HP1503.
PATRICi20594421. VBIHelPyl33062_1579.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000511 Genomic DNA. Translation: AAD08539.1.
PIRiG64707.
RefSeqiNP_208294.1. NC_000915.1.
WP_000650233.1. NC_018939.1.

3D structure databases

ProteinModelPortaliO26033.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-3099N.
IntActiO26033. 8 interactors.
MINTiMINT-178933.
STRINGi85962.HP1503.

Proteomic databases

PaxDbiO26033.
PRIDEiO26033.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAD08539; AAD08539; HP_1503.
GeneIDi899788.
KEGGiheo:C694_07785.
hpy:HP1503.
PATRICi20594421. VBIHelPyl33062_1579.

Phylogenomic databases

eggNOGiENOG4105C59. Bacteria.
COG2217. LUCA.
KOiK17686.
OMAiCLALESH.

Enzyme and pathway databases

BioCyciHPY:HP1503-MONOMER.

Family and domain databases

CDDicd00371. HMA. 1 hit.
Gene3Di2.70.150.10. 1 hit.
3.40.50.1000. 2 hits.
InterProiIPR021993. ATPase-cat-bd.
IPR018303. ATPase_P-typ_P_site.
IPR008250. ATPase_P-typ_transduc_dom_A.
IPR023214. HAD-like_dom.
IPR006121. HMA_dom.
IPR027256. P-typ_ATPase_IB.
IPR001757. P_typ_ATPase.
[Graphical view]
PfamiPF12156. ATPase-cat_bd. 1 hit.
PF00122. E1-E2_ATPase. 1 hit.
PF00403. HMA. 1 hit.
[Graphical view]
SUPFAMiSSF55008. SSF55008. 1 hit.
SSF56784. SSF56784. 2 hits.
TIGRFAMsiTIGR01525. ATPase-IB_hvy. 1 hit.
TIGR01494. ATPase_P-type. 1 hit.
PROSITEiPS00154. ATPASE_E1_E2. 1 hit.
PS50846. HMA_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiO26033_HELPY
AccessioniPrimary (citable) accession number: O26033
Entry historyi
Integrated into UniProtKB/TrEMBL: January 1, 1998
Last sequence update: January 1, 1998
Last modified: November 30, 2016
This is version 132 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.