O25943 (RECN_HELPY) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
DNA repair protein RecN

Alternative name(s):
Recombination protein N

Gene names

Name:	recN
Ordered Locus Names:	HP_1393

Organism

Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori) [Reference proteome] [HAMAP]

Taxonomic identifier

85962 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › delta/epsilon subdivisions › Epsilonproteobacteria › Campylobacterales › Helicobacteraceae › Helicobacter › Helicobacter pylori

Protein attributes

Sequence length	524 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	May be involved in recombinational repair of damaged DNA By similarity.
Sequence similarities	Belongs to the RecN family.

Ontologies

Keywords
Biological process	DNA damage DNA repair
Ligand	ATP-binding Nucleotide-binding
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	DNA recombination Inferred from electronic annotation. Source: InterPro DNA repair Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW nucleoside-triphosphatase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 524	524	DNA repair protein RecN		PRO_0000188019
Regions
	Nucleotide binding	36 – 43	8	ATP Potential

Sequences

	Sequence		Length	Mass (Da)
	O25943 [UniParc]. Last modified January 1, 1998. Version 1. Checksum: 1F78EBFF0CFCE68A	FASTA	524	59,565
	10 20 30 40 50 60 MRDFNNAQIT RLKVRQNAVF EKLDLEFKDG LSAISGASGV GKSVLIASLL GAFGLKESNA 70 80 90 100 110 120 SNIEVELIAP FLDTEEYGIF REDEHEPLVI SVIKKEKTRY FLNQTSLSKN TLKALLKGLI 130 140 150 160 170 180 KRLSNDRFSQ NELNDILMLS LLDGYIQNEN KAFSPLLGAL EEKFTRLEKL EKERRLLEDK 190 200 210 220 230 240 KRFQKDLEER LNFEKMKLER LDLKEDEYER LLEQKKLLSS KEKLNDKIAL ALEVLENTHK 250 260 270 280 290 300 ITHALESVGH SAEFLKSALL EASALLEKEQ AKLEECERLD IEKVLERLGM LSGIIKDYGS 310 320 330 340 350 360 IMHAKERLGH VKNELHNLKE IDSHCETYHK EIERLKTECL KLCEEISGFR KEYLAGFNAL 370 380 390 400 410 420 LSAKAKDLLL KSPSLVLEDA PMSEKGAQKL VLNLQNSQLE TLSSGEYSRL RLAFMLLEME 430 440 450 460 470 480 FLKDFKGVLV LDEMDSNLSG EESLAVSKAL ETLSSHSQIF AISHQVHIPA LAKNHILVFK 490 500 510 520 ENHKSLAKTL NNEERVLEIA RMIGGSENIE SAISFAKEKL KAQE

References

[1]

"The complete genome sequence of the gastric pathogen Helicobacter pylori." Tomb J.-F., White O., Kerlavage A.R., Clayton R.A., Sutton G.G., Fleischmann R.D., Ketchum K.A., Klenk H.-P., Gill S.R., Dougherty B.A., Nelson K.E., Quackenbush J., Zhou L., Kirkness E.F., Peterson S.N., Loftus B.J., Richardson D.L., Dodson R.J. , Khalak H.G., Glodek A., McKenney K., FitzGerald L.M., Lee N., Adams M.D., Hickey E.K., Berg D.E., Gocayne J.D., Utterback T.R., Peterson J.D., Kelley J.M., Cotton M.D., Weidman J.F., Fujii C., Bowman C., Watthey L., Wallin E., Hayes W.S., Borodovsky M., Karp P.D., Smith H.O., Fraser C.M., Venter J.C. Nature 388:539-547(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 700392 / 26695.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE000511 Genomic DNA. Translation: AAD08433.1.
PIR	A64694.
RefSeq	NP_208184.1. NC_000915.1. YP_006935317.1. NC_018939.1.
3D structure databases
ProteinModelPortal	O25943.
ModBase	Search...
Protein-protein interaction databases
DIP	DIP-3217N.
MINT	MINT-173060.
STRING	85962.HP1393.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAD08433; AAD08433; HP_1393.
GeneID	13870604. 899903.
KEGG	heo:C694_07195. hpy:HP1393.
PATRIC	20594173. VBIHelPyl33062_1457.
Phylogenomic databases
eggNOG	COG0497.
KO	K03631.
OMA	ENTHKIT.
ProtClustDB	CLSK872577.
Family and domain databases
InterPro	IPR003593. AAA+_ATPase. IPR004604. DNA_recomb/repair_RecN. IPR027417. P-loop_NTPase. IPR003395. RecF/RecN/SMC. [Graphical view]
PANTHER	PTHR11059. PTHR11059. 1 hit.
Pfam	PF02463. SMC_N. 1 hit. [Graphical view]
PIRSF	PIRSF003128. RecN. 1 hit.
SMART	SM00382. AAA. 1 hit. [Graphical view]
SUPFAM	SSF52540. SSF52540. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RECN_HELPY

Accession

Primary (citable) accession number: O25943

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 1, 2000
Last sequence update:	January 1, 1998
Last modified:	May 29, 2013
This is version 75 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program