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O25911

- PSD_HELPY

UniProt

O25911 - PSD_HELPY

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Protein

Phosphatidylserine decarboxylase proenzyme

Gene
psd, HP_1357
Organism
Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

Phosphatidyl-L-serine = phosphatidylethanolamine + CO2.UniRule annotation

Cofactori

Pyruvoyl group By similarity.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sitei235 – 2362Cleavage (non-hydrolytic) By similarity

GO - Molecular functioni

  1. phosphatidylserine decarboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. phosphatidylethanolamine biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Decarboxylase, Lyase

Keywords - Biological processi

Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism

Keywords - Ligandi

Pyruvate

Enzyme and pathway databases

BioCyciHPY:HP1357-MONOMER.
UniPathwayiUPA00558; UER00616.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphatidylserine decarboxylase proenzyme (EC:4.1.1.65)
Cleaved into the following 2 chains:
Gene namesi
Name:psd
Ordered Locus Names:HP_1357
OrganismiHelicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Taxonomic identifieri85962 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeHelicobacter
ProteomesiUP000000429: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 235235Phosphatidylserine decarboxylase beta chain By similarityPRO_0000029665Add
BLAST
Chaini236 – 26732Phosphatidylserine decarboxylase alpha chain By similarityPRO_0000029666Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei236 – 2361Pyruvic acid (Ser) By similarity

Keywords - PTMi

Zymogen

Proteomic databases

PRIDEiO25911.

Interactioni

Protein-protein interaction databases

DIPiDIP-3497N.
IntActiO25911. 1 interaction.
MINTiMINT-160147.
STRINGi85962.HP1357.

Structurei

3D structure databases

ProteinModelPortaliO25911.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0688.
KOiK01613.
OMAiPSLHKNN.
OrthoDBiEOG6B8XK4.

Family and domain databases

HAMAPiMF_00662. PS_decarb_type1.
InterProiIPR003817. PS_Dcarbxylase.
IPR005221. PS_decarb.
[Graphical view]
PANTHERiPTHR10067. PTHR10067. 1 hit.
PfamiPF02666. PS_Dcarbxylase. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00163. PS_decarb. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

O25911-1 [UniParc]FASTAAdd to Basket

« Hide

MVALSNALSR VFGSLAGYKF PSFIQKGINA LYVKIFKIDL SEFEPLENYR    50
SLNALFTRSL KKERPFDKSP NICIAPCDAL ITECAFLDND SALQIKGMPY 100
KAHELVGEIN PLSPSFFYAN FYLSPKDYHH YHAPCDLEIL EARYFAGKLL 150
PVNKPSLHKN NNLFVGNERV TLVAKDIQGN RLYFVAVGAL NVGKMRFNFD 200
KNIQTNAKAR FTQTYSYNPP IKVKKGDNLG NFEMGSTIVL FIQNTAFKDL 250
KEKNVKFGES IGEFHAN 267
Length:267
Mass (Da):30,201
Last modified:January 1, 1998 - v1
Checksum:i8CE79AC4126E8A4A
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE000511 Genomic DNA. Translation: AAD08399.1.
PIRiE64689.
RefSeqiNP_208149.1. NC_000915.1.
YP_006935279.1. NC_018939.1.

Genome annotation databases

EnsemblBacteriaiAAD08399; AAD08399; HP_1357.
GeneIDi13870566.
900346.
KEGGiheo:C694_07005.
hpy:HP1357.
PATRICi20594101. VBIHelPyl33062_1421.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE000511 Genomic DNA. Translation: AAD08399.1 .
PIRi E64689.
RefSeqi NP_208149.1. NC_000915.1.
YP_006935279.1. NC_018939.1.

3D structure databases

ProteinModelPortali O25911.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

DIPi DIP-3497N.
IntActi O25911. 1 interaction.
MINTi MINT-160147.
STRINGi 85962.HP1357.

Proteomic databases

PRIDEi O25911.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAD08399 ; AAD08399 ; HP_1357 .
GeneIDi 13870566.
900346.
KEGGi heo:C694_07005.
hpy:HP1357.
PATRICi 20594101. VBIHelPyl33062_1421.

Phylogenomic databases

eggNOGi COG0688.
KOi K01613.
OMAi PSLHKNN.
OrthoDBi EOG6B8XK4.

Enzyme and pathway databases

UniPathwayi UPA00558 ; UER00616 .
BioCyci HPY:HP1357-MONOMER.

Family and domain databases

HAMAPi MF_00662. PS_decarb_type1.
InterProi IPR003817. PS_Dcarbxylase.
IPR005221. PS_decarb.
[Graphical view ]
PANTHERi PTHR10067. PTHR10067. 1 hit.
Pfami PF02666. PS_Dcarbxylase. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00163. PS_decarb. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700392 / 26695.

Entry informationi

Entry nameiPSD_HELPY
AccessioniPrimary (citable) accession number: O25911
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 3, 2003
Last sequence update: January 1, 1998
Last modified: September 3, 2014
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Helicobacter pylori
    Helicobacter pylori (strain 26695): entries and gene names
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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