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Protein

Biopolymer transport protein ExbD

Gene

exbD

Organism
Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates.By similarity

GO - Molecular functioni

  1. transporter activity Source: InterPro

GO - Biological processi

  1. protein transport Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Protein transport, Transport

Enzyme and pathway databases

BioCyciHPY:HP1340-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Biopolymer transport protein ExbD
Gene namesi
Name:exbD
Ordered Locus Names:HP_1340
OrganismiHelicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Taxonomic identifieri85962 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeHelicobacter
ProteomesiUP000000429 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 1212CytoplasmicSequence AnalysisAdd
BLAST
Transmembranei13 – 3321HelicalSequence AnalysisAdd
BLAST
Topological domaini34 – 12996PeriplasmicSequence AnalysisAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 129129Biopolymer transport protein ExbDPRO_0000129122Add
BLAST

Proteomic databases

PRIDEiO25898.

Interactioni

Subunit structurei

The accessory proteins ExbB and ExbD seem to form a complex with TonB.By similarity

Protein-protein interaction databases

DIPiDIP-3143N.
IntActiO25898. 1 interaction.
MINTiMINT-175819.
STRINGi85962.HP1340.

Structurei

3D structure databases

ProteinModelPortaliO25898.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ExbD/TolR family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0848.
KOiK03559.
OMAiWDKEQKV.
OrthoDBiEOG6P5ZH2.

Family and domain databases

InterProiIPR003400. ExbD.
IPR014171. TonB_ExbD_2.
[Graphical view]
PfamiPF02472. ExbD. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02804. ExbD_2. 1 hit.

Sequencei

Sequence statusi: Complete.

O25898-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKSIRRGDGL NVVPFIDIML VLLAIVLSIS TFIAQGKIKV SLPNAKNAEK
60 70 80 90 100
SQPNDQKVVV ISVDEHDNIF VDDKPMNLEA LSAVVKQTDP KTLIDLKSDK
110 120
SSRFETFISI MDILKEHNHE NFSISTQAQ
Length:129
Mass (Da):14,377
Last modified:January 1, 1998 - v1
Checksum:iD575395C4DDF28E9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000511 Genomic DNA. Translation: AAD08382.1.
PIRiD64687.
RefSeqiNP_208132.1. NC_000915.1.
YP_006935261.1. NC_018939.1.

Genome annotation databases

EnsemblBacteriaiAAD08382; AAD08382; HP_1340.
GeneIDi898892.
KEGGiheo:C694_06915.
hpy:HP1340.
PATRICi20594063. VBIHelPyl33062_1402.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000511 Genomic DNA. Translation: AAD08382.1.
PIRiD64687.
RefSeqiNP_208132.1. NC_000915.1.
YP_006935261.1. NC_018939.1.

3D structure databases

ProteinModelPortaliO25898.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-3143N.
IntActiO25898. 1 interaction.
MINTiMINT-175819.
STRINGi85962.HP1340.

Proteomic databases

PRIDEiO25898.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAD08382; AAD08382; HP_1340.
GeneIDi898892.
KEGGiheo:C694_06915.
hpy:HP1340.
PATRICi20594063. VBIHelPyl33062_1402.

Phylogenomic databases

eggNOGiCOG0848.
KOiK03559.
OMAiWDKEQKV.
OrthoDBiEOG6P5ZH2.

Enzyme and pathway databases

BioCyciHPY:HP1340-MONOMER.

Family and domain databases

InterProiIPR003400. ExbD.
IPR014171. TonB_ExbD_2.
[Graphical view]
PfamiPF02472. ExbD. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02804. ExbD_2. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700392 / 26695.

Entry informationi

Entry nameiEXBD_HELPY
AccessioniPrimary (citable) accession number: O25898
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: January 1, 1998
Last modified: April 1, 2015
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Helicobacter pylori
    Helicobacter pylori (strain 26695): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.