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O25897

- EXBB_HELPY

UniProt

O25897 - EXBB_HELPY

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Protein

Biopolymer transport protein ExbB

Gene
exbB, HP_1339
Organism
Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates. Protects ExbD from proteolytic degradation and functionally stabilizes TonB By similarity.

GO - Molecular functioni

  1. protein transporter activity Source: InterPro
Complete GO annotation...

Keywords - Biological processi

Protein transport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Biopolymer transport protein ExbB
Gene namesi
Name:exbB
Ordered Locus Names:HP_1339
OrganismiHelicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Taxonomic identifieri85962 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeHelicobacter
ProteomesiUP000000429: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei13 – 3321Helical; Reviewed predictionAdd
BLAST
Transmembranei67 – 8721Helical; Reviewed predictionAdd
BLAST
Transmembranei101 – 12121Helical; Reviewed predictionAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 145145Biopolymer transport protein ExbBPRO_0000145803Add
BLAST

Interactioni

Subunit structurei

The accessory proteins ExbB and ExbD seem to form a complex with TonB By similarity.

Protein-protein interaction databases

STRINGi85962.HP1339.

Family & Domainsi

Sequence similaritiesi

Belongs to the ExbB/TolQ family.

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0811.
KOiK03561.
OMAiERIIFYS.
OrthoDBiEOG6JDWB5.

Family and domain databases

InterProiIPR002898. MotA_ExbB_proton_chnl.
IPR014172. TonB_ExbB_2.
[Graphical view]
PfamiPF01618. MotA_ExbB. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02805. exbB2. 1 hit.

Sequencei

Sequence statusi: Complete.

O25897-1 [UniParc]FASTAAdd to Basket

« Hide

MGGFSVGMLK DYVDIFVFAV LGVASFLALW FAIERVIFYS KVDLKAYDDI    50
DALNLDLTKN LTILYVIFSN APYVGLLGTV LGIMVIFYDM GVSGGMDAKT 100
IMVGLSLALK ATALGLAVAI PTLIAYNSLL RKSDVLSEKF RIMKK 145
Length:145
Mass (Da):15,804
Last modified:December 1, 2000 - v2
Checksum:iA44BB5BA436F9540
GO

Sequence cautioni

The sequence AAD08381.1 differs from that shown. Reason: Erroneous initiation.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE000511 Genomic DNA. Translation: AAD08381.1. Different initiation.
PIRiC64687.
RefSeqiNP_208131.1. NC_000915.1.
YP_006935260.1. NC_018939.1.

Genome annotation databases

EnsemblBacteriaiAAD08381; AAD08381; HP_1339.
GeneIDi13870547.
898784.
KEGGiheo:C694_06910.
hpy:HP1339.
PATRICi20594061. VBIHelPyl33062_1401.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE000511 Genomic DNA. Translation: AAD08381.1 . Different initiation.
PIRi C64687.
RefSeqi NP_208131.1. NC_000915.1.
YP_006935260.1. NC_018939.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 85962.HP1339.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAD08381 ; AAD08381 ; HP_1339 .
GeneIDi 13870547.
898784.
KEGGi heo:C694_06910.
hpy:HP1339.
PATRICi 20594061. VBIHelPyl33062_1401.

Phylogenomic databases

eggNOGi COG0811.
KOi K03561.
OMAi ERIIFYS.
OrthoDBi EOG6JDWB5.

Family and domain databases

InterProi IPR002898. MotA_ExbB_proton_chnl.
IPR014172. TonB_ExbB_2.
[Graphical view ]
Pfami PF01618. MotA_ExbB. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR02805. exbB2. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700392 / 26695.

Entry informationi

Entry nameiEXBB_HELPY
AccessioniPrimary (citable) accession number: O25897
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: December 1, 2000
Last modified: September 3, 2014
This is version 74 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Helicobacter pylori
    Helicobacter pylori (strain 26695): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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