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Protein

Biopolymer transport protein ExbB

Gene

exbB

Organism
Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates. Protects ExbD from proteolytic degradation and functionally stabilizes TonB (By similarity).By similarity

GO - Molecular functioni

  1. protein transporter activity Source: InterPro
Complete GO annotation...

Keywords - Biological processi

Protein transport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Biopolymer transport protein ExbB
Gene namesi
Name:exbB
Ordered Locus Names:HP_1339
OrganismiHelicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Taxonomic identifieri85962 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeHelicobacter
ProteomesiUP000000429 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei13 – 3321HelicalSequence AnalysisAdd
BLAST
Transmembranei67 – 8721HelicalSequence AnalysisAdd
BLAST
Transmembranei101 – 12121HelicalSequence AnalysisAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 145145Biopolymer transport protein ExbBPRO_0000145803Add
BLAST

Interactioni

Subunit structurei

The accessory proteins ExbB and ExbD seem to form a complex with TonB.By similarity

Protein-protein interaction databases

STRINGi85962.HP1339.

Family & Domainsi

Sequence similaritiesi

Belongs to the ExbB/TolQ family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0811.
KOiK03561.
OMAiERIIFYS.
OrthoDBiEOG6JDWB5.

Family and domain databases

InterProiIPR002898. MotA_ExbB_proton_chnl.
IPR014172. TonB_ExbB_2.
[Graphical view]
PfamiPF01618. MotA_ExbB. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02805. exbB2. 1 hit.

Sequencei

Sequence statusi: Complete.

O25897-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGGFSVGMLK DYVDIFVFAV LGVASFLALW FAIERVIFYS KVDLKAYDDI
60 70 80 90 100
DALNLDLTKN LTILYVIFSN APYVGLLGTV LGIMVIFYDM GVSGGMDAKT
110 120 130 140
IMVGLSLALK ATALGLAVAI PTLIAYNSLL RKSDVLSEKF RIMKK
Length:145
Mass (Da):15,804
Last modified:November 30, 2000 - v2
Checksum:iA44BB5BA436F9540
GO

Sequence cautioni

The sequence AAD08381.1 differs from that shown. Reason: Erroneous initiation. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000511 Genomic DNA. Translation: AAD08381.1. Different initiation.
PIRiC64687.
RefSeqiNP_208131.1. NC_000915.1.
YP_006935260.1. NC_018939.1.

Genome annotation databases

EnsemblBacteriaiAAD08381; AAD08381; HP_1339.
GeneIDi13870547.
898784.
KEGGiheo:C694_06910.
hpy:HP1339.
PATRICi20594061. VBIHelPyl33062_1401.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000511 Genomic DNA. Translation: AAD08381.1. Different initiation.
PIRiC64687.
RefSeqiNP_208131.1. NC_000915.1.
YP_006935260.1. NC_018939.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi85962.HP1339.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAD08381; AAD08381; HP_1339.
GeneIDi13870547.
898784.
KEGGiheo:C694_06910.
hpy:HP1339.
PATRICi20594061. VBIHelPyl33062_1401.

Phylogenomic databases

eggNOGiCOG0811.
KOiK03561.
OMAiERIIFYS.
OrthoDBiEOG6JDWB5.

Family and domain databases

InterProiIPR002898. MotA_ExbB_proton_chnl.
IPR014172. TonB_ExbB_2.
[Graphical view]
PfamiPF01618. MotA_ExbB. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02805. exbB2. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700392 / 26695.

Entry informationi

Entry nameiEXBB_HELPY
AccessioniPrimary (citable) accession number: O25897
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 14, 1998
Last sequence update: November 30, 2000
Last modified: January 6, 2015
This is version 77 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Helicobacter pylori
    Helicobacter pylori (strain 26695): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.