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O25897

- EXBB_HELPY

UniProt

O25897 - EXBB_HELPY

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Protein
Biopolymer transport protein ExbB
Gene
exbB, HP_1339
Organism
Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates. Protects ExbD from proteolytic degradation and functionally stabilizes TonB By similarity.

GO - Molecular functioni

  1. protein transporter activity Source: InterPro
Complete GO annotation...

GO - Biological processi

    Complete GO annotation...

    Keywords - Biological processi

    Protein transport, Transport

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Biopolymer transport protein ExbB
    Gene namesi
    Name:exbB
    Ordered Locus Names:HP_1339
    OrganismiHelicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
    Taxonomic identifieri85962 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeHelicobacter
    ProteomesiUP000000429: Chromosome

    Subcellular locationi

    Topology

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei13 – 3321Helical; Reviewed prediction
    Add
    BLAST
    Transmembranei67 – 8721Helical; Reviewed prediction
    Add
    BLAST
    Transmembranei101 – 12121Helical; Reviewed prediction
    Add
    BLAST

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. plasma membrane Source: UniProtKB-SubCell
    Complete GO annotation...

    Keywords - Cellular componenti

    Cell inner membrane, Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 145145Biopolymer transport protein ExbB
    PRO_0000145803Add
    BLAST

    Interactioni

    Subunit structurei

    The accessory proteins ExbB and ExbD seem to form a complex with TonB By similarity.

    Protein-protein interaction databases

    STRINGi85962.HP1339.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ExbB/TolQ family.

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiCOG0811.
    KOiK03561.
    OMAiERIIFYS.
    OrthoDBiEOG6JDWB5.

    Family and domain databases

    InterProiIPR002898. MotA_ExbB_proton_chnl.
    IPR014172. TonB_ExbB_2.
    [Graphical view]
    PfamiPF01618. MotA_ExbB. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR02805. exbB2. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    O25897-1 [UniParc]FASTAAdd to Basket

    « Hide

    MGGFSVGMLK DYVDIFVFAV LGVASFLALW FAIERVIFYS KVDLKAYDDI    50
    DALNLDLTKN LTILYVIFSN APYVGLLGTV LGIMVIFYDM GVSGGMDAKT 100
    IMVGLSLALK ATALGLAVAI PTLIAYNSLL RKSDVLSEKF RIMKK 145
    Length:145
    Mass (Da):15,804
    Last modified:December 1, 2000 - v2
    Checksum:iA44BB5BA436F9540
    GO

    Sequence cautioni

    The sequence AAD08381.1 differs from that shown. Reason: Erroneous initiation.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE000511 Genomic DNA. Translation: AAD08381.1. Different initiation.
    PIRiC64687.
    RefSeqiNP_208131.1. NC_000915.1.
    YP_006935260.1. NC_018939.1.

    Genome annotation databases

    EnsemblBacteriaiAAD08381; AAD08381; HP_1339.
    GeneIDi13870547.
    898784.
    KEGGiheo:C694_06910.
    hpy:HP1339.
    PATRICi20594061. VBIHelPyl33062_1401.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE000511 Genomic DNA. Translation: AAD08381.1 . Different initiation.
    PIRi C64687.
    RefSeqi NP_208131.1. NC_000915.1.
    YP_006935260.1. NC_018939.1.

    3D structure databases

    ModBasei Search...

    Protein-protein interaction databases

    STRINGi 85962.HP1339.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAD08381 ; AAD08381 ; HP_1339 .
    GeneIDi 13870547.
    898784.
    KEGGi heo:C694_06910.
    hpy:HP1339.
    PATRICi 20594061. VBIHelPyl33062_1401.

    Phylogenomic databases

    eggNOGi COG0811.
    KOi K03561.
    OMAi ERIIFYS.
    OrthoDBi EOG6JDWB5.

    Family and domain databases

    InterProi IPR002898. MotA_ExbB_proton_chnl.
    IPR014172. TonB_ExbB_2.
    [Graphical view ]
    Pfami PF01618. MotA_ExbB. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR02805. exbB2. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 700392 / 26695.

    Entry informationi

    Entry nameiEXBB_HELPY
    AccessioniPrimary (citable) accession number: O25897
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: December 15, 1998
    Last sequence update: December 1, 2000
    Last modified: September 3, 2014
    This is version 74 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Helicobacter pylori
      Helicobacter pylori (strain 26695): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3

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