O25850 (O25850_HELPY) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
NADH-quinone oxidoreductase subunit RuleBase RU003639
EC=1.6.99.5 RuleBase RU003639

Gene names

Ordered Locus Names:

HP_1260

Organism

Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)

Taxonomic identifier

85962 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Epsilonproteobacteria › Campylobacterales › Helicobacteraceae › Helicobacter

Protein attributes

Sequence length	133 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain By similarity. RuleBase RU003639
Catalytic activity	NADH + quinone = NAD+ + quinol. RuleBase RU003639
Subcellular location	Membrane; Multi-pass membrane protein By similarity RuleBase RU003639.
Sequence similarities	Belongs to the complex I subunit 3 family. RuleBase RU003639

Ontologies

Keywords
Cellular component	Membrane
Domain	Transmembrane RuleBase RU003639
Ligand	NAD RuleBase RU003639 Ubiquinone EMBL AAD08306.1
Molecular function	Oxidoreductase RuleBase RU003639
PTM	Quinone RuleBase RU003639
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	NADH dehydrogenase (ubiquinone) activity Inferred from electronic annotation. Source: InterPro quinone binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	O25850 [UniParc]. Last modified January 1, 1998. Version 1. Checksum: 7F737775E0D65530	FASTA	133	15,619
	10 20 30 40 50 60 MQQATEALNH PYFGVFVLLV FTFWVFNLTL RIQRFLSRKM AQKKGEKLKL APYECGPVAL 70 80 90 100 110 120 KQPNRVSHHF YIMAMLFILF DVEIVFMFPW AIGFKKLGLF GLVEMLGFVF FLTIGFIYAL 130 KRNALSWQKL EVK

References

[1]

"The complete genome sequence of the gastric pathogen Helicobacter pylori." Tomb J.-F., White O., Kerlavage A.R., Clayton R.A., Sutton G.G., Fleischmann R.D., Ketchum K.A., Klenk H.-P., Gill S.R., Dougherty B.A., Nelson K.E., Quackenbush J., Zhou L., Kirkness E.F., Peterson S.N., Loftus B.J., Richardson D.L., Dodson R.J. , Khalak H.G., Glodek A., McKenney K., FitzGerald L.M., Lee N., Adams M.D., Hickey E.K., Berg D.E., Gocayne J.D., Utterback T.R., Peterson J.D., Kelley J.M., Cotton M.D., Weidman J.F., Fujii C., Bowman C., Watthey L., Wallin E., Hayes W.S., Borodovsky M., Karp P.D., Smith H.O., Fraser C.M., Venter J.C. Nature 388:539-547(1997) [PubMed: 9252185] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 700392 / 26695.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE000511 Genomic DNA. Translation: AAD08306.1.
PIR	D64677.
RefSeq	NP_208052.1. NC_000915.1.
3D structure databases
ProteinModelPortal	O25850.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	900263.
GenomeReviews	Gene locus HP_1260 in contig AE000511_GR.
KEGG	hpy:HP1260.
NMPDR	fig|85962.1.peg.1248.
PATRIC	20593897. VBIHelPyl33062_1319.
TIGR	HP_1260.
Phylogenomic databases
HOGENOM	HBG605540.
OMA	PWAIDFK.
ProtClustDB	PRK08489.
Family and domain databases
InterPro	IPR000440. NADH_UbQ/plastoQ_OxRdtase_su3. [Graphical view]
KO	K00330.
PANTHER	PTHR11058. Oxidored_q4. 1 hit.
Pfam	PF00507. Oxidored_q4. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

O25850_HELPY

Accession

Primary (citable) accession number: O25850

Entry history

Integrated into UniProtKB/TrEMBL:	January 1, 1998
Last sequence update:	January 1, 1998
Last modified:	December 14, 2011
This is version 62 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)